Blood lead levels in patients with lead shot retained in the appendix

1988 ◽  
Vol 29 (6) ◽  
pp. 745-746 ◽  
Author(s):  
H. H. T. Madsen ◽  
T. Skjødt ◽  
P. J. Jørgensen ◽  
P. Grandjean
1988 ◽  
Vol 29 (6) ◽  
pp. 745-746
Author(s):  
H. H. T. Madsen ◽  
T. Skjødt ◽  
P. J. Jørgensen ◽  
P. Grandjean

Seven patients with one or two lead shots retained in the appendix were identified by radiography. For each case, two sex- and age-matched control patients without lead shot in the appendix were found. None of the 7 patients with lead shot in the appendix had blood lead levels (median 0.55 μmol/l) approaching the toxic levels, but they averaged almost twice the levels of the controls (median 0.29 μmol/l). Thus, lead shots may add to individual lead exposures, and blood lead analysis should be performed, at least when more than a few lead shots are present.


1988 ◽  
Vol 29 (6) ◽  
pp. 745-746 ◽  
Author(s):  
H. H. T. Madsen ◽  
T. Skjødt ◽  
P. J. Jørgensen ◽  
P. Grandjean

Author(s):  
Nicole Lewis ◽  
Theodore C. Nichols ◽  
Christina Lilley ◽  
Douglas E. Roscoe ◽  
Jan Lovy

Waterfowl managers first recognized the problem of lead poisoning in ducks from the ingestion of spent lead shot (pellets) over 100 years ago. The phase-out of lead shot for waterfowl hunting began in the Atlantic Flyway in the 1970s. Lead shot was subsequently banned throughout the United States and Canada prior to 2000. We compared blood-lead levels in American black ducks Anas rubripes wintering in coastal New Jersey in 1978, prior to the lead ban, and in 2017, about 39 years after lead shot was first banned for use in Atlantic coastal marshes and 27 years after it was banned for waterfowl hunting in New Jersey. The prevalence of blood-lead > 0.2 ppm, a level commonly used to indicate lead exposure, declined nearly four-fold from 1978 (79%) to 2017 (20%). We found no significant differences in the prevalence of birds with blood-lead levels > 0.2 ppm between sexes in either year or between age classes in 2017. The prevalence of ducks with blood-lead levels > 1.0 ppm, considered clinically evident toxicity, declined from 19% in 1978 to 1% in 2017. Our study provides further evidence that the ban on the use of lead shot over 20 years ago throughout North America has resulted in lower blood-lead levels in waterfowl. Notwithstanding, we still found evidence of lead exposure in black ducks in 2017, which warrants further investigation.


Author(s):  
Nam Soo Kim ◽  
Sung Woo Choi ◽  
Jin Ho Kim ◽  
Jung O Ham ◽  
Hae Yoon Park ◽  
...  

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Sahar Mahmoud Shawky ◽  
Reeham Abdel Aziz Abdel Hamid ◽  
Lina Essam Khedr

Abstract Background Pruritus is a common and often distressing symptom in patients with chronic kidney disease. Though the pathogenesis of uremic pruritus remains poorly understood, systemic inflammation has presented itself as one of the possible explanations. High blood lead levels (BLLs) have been noted to be associated with inflammation and poor nutritional status in hemodialysis patients. Our aim is to study the relation between blood lead levels and uremic pruritus. This is a cross-sectional study that enrolled 50 patients; all were on regular hemodialysis 3 times per week for at least 6 months. Patients were divided into 2 groups, group 1 (n =10) with no pruritus and group 2 (n=40) with varying degrees of pruritus. Group 2 was further divided according to intensity of pruritus by visual analog score (VAS) into mild (n=10), moderate (n=20), and severe pruritus (n=10). Results There was a significant difference in serum lead levels and ferritin levels between groups 1 and 2 (p value < 0.01 and < 0.05, respectively). There was a statistically significant difference in serum lead levels in the groups with varying intensity of pruritus, having higher serum lead levels in patients who exhibited severe pruritus (p value < 0.005) Moreover, a statistically significant relation between elevated blood lead levels and the duration of dialysis was observed in this study. Conclusion Uremic pruritus is a multi-factorial phenomenon, and our study showed that blood lead levels in hemodialysis patients might be associated with increased intensity of pruritus.


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