Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness

2019 ◽  
Author(s):  
Keyword(s):  
Optic Nerve ◽  
Fluid Responsiveness ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Nerve Sheath

scholarly journals Prospective Study: Optic Nerve Sheath ‎Diameter in Prediction of Fluid ‎Responsiveness in Sepsis Patients

2021 ◽  
pp. 244-253
Author(s):  
Hadeel Ibraheim Elsagheir ◽  
Abd Elaziz Hamed El Badawy ◽  
Reda Sobhi Salama Abd Alrahman ◽  
Mohamed Samir Abd El Ghafar
Keyword(s):  
Optic Nerve ◽  
Fluid Responsiveness ◽  
Demographic Data ◽  
Optic Nerve Sheath Diameter ◽  
Mean Value ◽  
Optic Nerve Sheath ◽  
Surgical Intensive Care Unit ◽  
Surgical Intensive Care ◽  
Nerve Sheath ◽  
The Mean

Background: Sepsis is a life-threatening disease caused by the body's reaction to infection, which results in tissue destruction, organ failure, and death. Sepsis affects at least 30 million people worldwide each year, with 6 million people dying as a result. The goal of the research was to see whether the measurement of the Optic Nerve Sheath Diameter (ONSD) could be used to predict fluid responsiveness in hemodynamically unstable individuals.‎ Patients and Methods: This prospective observational (cohort) study was conducted at Tanta ‎University Hospitals in the Surgical Intensive Care Unit for 6 months at least ‎after approval from institutional ethics committee‎. Results: Demographic data (sex, illiteracy, height, BMI) in our patients of the study there ‎were 34 (81%) male, 8 (19%) female, the age was average from 50.33 (±8.63 ‎SD) with range (25-65), 9 (21.4%) illiterate, 10 (23.8%) primary, 18 (42.9%) ‎secondary, 5 (11.9%) university, the mean value of weight 80.29 (±9.45 SD) ‎with range (60.7-98.8), the mean value of height 170.57 (±7.24 SD) with ‎range (157-182), the mean value of BMI 27.54 (±2.19 SD) with range (24.3-‎‎32).‎ Conclusion: In patients with sepsis, ocular ultrasonography appears to be a non-invasive and simple-to-learn technique for assessing overall fluid status. It may be particularly effective in finding those septic individuals who should avoid further fluid intake since it could cause pulmonary edema or other fluid-related problems.

Optic nerve sheath diameter changes at high altitude and in acute mountain sickness: meta-regression analyses

2020 ◽  
pp. bjophthalmol-2020-317717
Author(s):  
Tou-Yuan Tsai ◽  
George Gozari ◽  
Yung-Cheng Su ◽  
Yi-Kung Lee ◽  
Yu-Kang Tu
Keyword(s):  
Optic Nerve ◽  
High Altitude ◽  
Acute Mountain Sickness ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Cochrane Library ◽  
Regression Analyses ◽  
Spline Regression ◽  
Nerve Sheath ◽  
Mountain Sickness

Background/aimsTo assess changes in optic nerve sheath diameter (ONSD) at high altitude and in acute mountain sickness (AMS).MethodsCochrane Library, EMBASE, Google Scholar and PubMed were searched for articles published from their inception to 31st of July 2020. Outcome measures were mean changes of ONSD at high altitude and difference in ONSD change between subjects with and without AMS. Meta-regressions were conducted to investigate the relation of ONSD change to altitude and time spent at that altitude.ResultsEight studies with 248 participants comparing ONSD from sea level to high altitude, and five studies with 454 participants comparing subjects with or without AMS, were included. ONSD increased by 0.14 mm per 1000 m after adjustment for time (95% CI: 0.10 to 0.18; p<0.01). Restricted cubic spline regression revealed an almost linear relation between ONSD change and time within 2 days. ONSD was greater in subjects with AMS (mean difference=0.47; 95% CI: 0.14 to 0.80; p=0.01; I2=89.4%).ConclusionOur analysis shows that ONSD changes correlate with altitude and tend to increase in subjects with AMS. Small study number and high heterogeneity are the limitations of our study. Further large prospective studies are required to verify our findings.

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