Deep brain stimulation of the orbitofrontal projections for the treatment of intermittent explosive disorder

2010 ◽  
Vol 29 (2) ◽  
pp. E11 ◽  
Author(s):  
Jason H. Maley ◽  
Jorge E. Alvernia ◽  
Edison P. Valle ◽  
Donald Richardson
Keyword(s):  
Early Childhood ◽  
Deep Brain Stimulation ◽  
Limbic System ◽  
Brain Stimulation ◽  
Intermittent Explosive Disorder ◽  
Environmental Perturbation ◽  
History Of ◽  
Patient’S History ◽  
Deep Brain ◽  
Stimulation Of

Intermittent explosive disorder (IED) is characterized by a dysfunction in the greater limbic system leading an individual to experience sudden aggressive behavior with little or no environmental perturbation. This report describes a procedure for the treatment of IED in a 19-year-old woman with a history of IED, having had episodes of severe violent attacks against family, dating to early childhood. Due to the severity and intractability of the illness, deep brain stimulation was performed, targeting the orbitofrontal projections to the hypothalamus. The patient's history and the procedure, management, and rationale are described in detail.

Efficacy of unilateral deep brain stimulation of the thalamic ventralis intermedius nucleus in a patient with bipolar disorder associated with Klinefelter syndrome and essential tremor

2000 ◽  
Vol 93 (1) ◽  
pp. 127-128 ◽  
Author(s):  
Albert E. Telfeian ◽  
John A. Boockvar ◽  
Tanya Simuni ◽  
Jurg Jaggi ◽  
Brett Skolnick ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Deep Brain Stimulation ◽  
Essential Tremor ◽  
Brain Stimulation ◽  
Genetic Basis ◽  
Klinefelter Syndrome ◽  
Content Type ◽  
History Of ◽  
Deep Brain ◽  
Stimulation Of

✓ Deep brain stimulation (DBS) of the ventralis intermedius nucleus (Vim) is a safe and effective treatment for essential tremor. Bipolar disorder and essential tremor had each been reported to occur in association with Klinefelter syndrome but the three diseases have been reported to occur together in only one patient. The genetic basis and natural history of these disorders are not completely understood and may be related rather than coincidental. The authors report on a 23-year-old man with Klinefelter syndrome (47,XXY) and bipolar disorder who was treated successfully with unilateral DBS of the thalamic Vim for essential tremor.

scholarly journals Deep brain stimulation of the ventralis intermedius nucleus for the treatment of essential tremor

2017 ◽  
Vol 42 (videosuppl2) ◽  
pp. V3
Author(s):  
Alexander G. Chartrain ◽  
Ahmed J. Awad ◽  
Jonathan J. Rasouli ◽  
Robert J. Rothrock ◽  
Brian H. Kopell
Keyword(s):  
Deep Brain Stimulation ◽  
Physical Examination ◽  
Essential Tremor ◽  
Brain Stimulation ◽  
Optimal Trajectory ◽  
Lesion Effect ◽  
Lead Placement ◽  
History Of ◽  
Deep Brain ◽  
Stimulation Of

A 59-year-old woman with a 30-year history of essential tremor refractory to medical therapy underwent staged deep brain stimulation of the ventralis intermedius nucleus of the thalamus (VIM). Left-sided lead placement was performed first. Once in the operating room, microelectrode recording (MER) was performed to confirm the appropriate trajectory and identify the VIM border with the ventralis caudalis nucleus. MER was repeated after repositioning 2 mm anteriorly to reduce the likelihood of stimulation-induced paresthesias. Physical examination prior to permanent lead placement demonstrated micro-lesion effect, suggesting optimal trajectory. After implantation of the permanent lead, physical examination showed excellent results.The video can be found here: https://youtu.be/nn3KRdmRCZ4.

scholarly journals Troubleshooting in hospitalized Parkinson's disease patients with a history of deep brain stimulation of the subthalamic nucleus

2014 ◽  
Vol 2 (6) ◽  
pp. 188-192 ◽  
Author(s):  
Genko Oyama ◽  
Yasushi Shimo ◽  
Atsushi Umemura ◽  
Natsuko Nishikawa ◽  
Asuka Nakajima ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Subthalamic Nucleus ◽  
Brain Stimulation ◽  
History Of ◽  
Deep Brain ◽  
Stimulation Of
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