scholarly journals Functional State Spaces and their Formation in Systems from Biological Organisms to the Physical Universe

2021 ◽  
Author(s):  
Andy E Williams

This paper explores how the emerging science of Human-Centric Functional Modeling or HCFM provides a universal approach to modeling systems that is hypothesized to maximize human capacity to understand and navigate the complexity of systems, and how it facilitates a kind of biomimicry in which the human organism is represented in terms of abstract mathematical spaces that can be used to define simple expressions to represent properties like “complexity” for human systems like cognition, where the same spaces can be used to represent other systems, including the entire physical universe, so that the underlying equivalence of the representations allows the same mathematical expressions to define the same properties where applicable for these very different systems, and therefore allows deep insights to potentially be gained about these systems through looking inward to observe how one’s own cognition functions from one’s first person experience. This paper explores how from this Human-Centric Functional Modeling perspective the properties governing the evolution of life in its functional state space might also govern the formation of the universe in its own functional state space. Human-Centric Functional Modeling also has other significant benefits, one is that in defining behavior in terms of mathematical spaces it enables all the mathematical disciplines that apply to such spaces (e.g. functor theory, category theory, process theory) to be used to understand and navigate the relationships between concepts described in those spaces. Another is that in providing a self-contained representation of the human meaning of any entity, including of any region in the physical universe, Human-Centric Functional Modeling potentially defines the first complete semantic representation of concepts, physical objects, or any other entities represented in a functional state space. When applied to the physical universe this implies that all theoretical or experimental data can be stored in that single model and all theories tested against it to increase capacity to impact a research question. When applied to other systems semantic modeling has equally important implications. Another benefit of Human-Centric Functional Modeling is that it is also a human-centric expression of “constructor theory”, which in the case of physical systems enables accurate predictions to be made about their physical behavior simply from observations of their functions, without needing to understand the specific physics through which the functions are implemented in those systems.

1975 ◽  
Vol 30 (11) ◽  
pp. 1361-1371 ◽  
Author(s):  
H. Stumpf ◽  
K. Scheerer

Functional quantum theory is defined by an isomorphism of the state space H of a conventional quantum theory into an appropriate functional state space D It is a constructive approach to quantum theory in those cases where the state spaces H of physical eigenstates cannot be calculated explicitly like in nonlinear spinor field quantum theory. For the foundation of functional quantum theory appropriate functional state spaces have to be constructed which have to be representation spaces of the corresponding invariance groups. In this paper, this problem is treated for the spinor field. Using anticommuting source operator, it is shown that the construction problem of these spaces is tightly connected with the construction of appropriate relativistic function spaces. This is discussed in detail and explicit representations of the function spaces are given. Imposing no artificial restrictions it follows that the resulting functional spaces are indefinite. Physically the indefiniteness results from the inclusion of tachyon states. It is reasonable to assume a tight connection of these tachyon states with the ghost states introduced by Heisenberg for the regularization of the nonrenormalizable spinor theory


Author(s):  
Gennady M. Aldonin ◽  
◽  
Vasily V. Cherepanov ◽  

In domestic and foreign practice, a great deal of experience has been accumulated in the creation of means for monitoring the functional state of the human body. The existing complexes mainly analyze the electrocardiogram, blood pressure and a number of other physiological parameters. Diagnostics is often based on formal statistical data which are not always correct due to the nonstationarity of bioprocesses and without taking into account their physical nature. An urgent task of monitoring the state of the cardiovascular system is the creation of effective algorithms for computer technologies to process biosignals based on nonlinear dynamic models of body systems since biosystems and bioprocesses have a nonlinear nature and fractal structure. The nervous and muscular systems of the heart, the vascular and bronchial systems of the human body are examples of such structures. The connection of body systems with their organization in the form of self-similar fractal structures with scaling close to the “golden ratio” makes it possible to diagnose them topically. It is possible to obtain detailed information about the state of the human body’s bio-networks for topical diagnostics on the basis of the wavelet analysis of biosignals (the so-called wavelet-introscopy). With the help of wavelet transform, it is possible to reveal the structure of biosystems and bioprocesses, as a picture of the lines of local extrema of wavelet diagrams of biosignals. Mathematical models and software for wavelet introscopy make it possible to extract additional information from biosignals about the state of biosystems. Early detection of latent forms of diseases using wavelet introscopy can shorten the cure time and reduce the consequences of disorders of the functional state of the body (FSO), and reduce the risk of disability. Taking into account the factors of organizing the body’s biosystems in the form of self-similar fractal structures with a scaling close to the “golden ratio” makes it possible to create a technique for topical diagnostics of the most important biosystems of the human body.


2005 ◽  
Vol 12 (2) ◽  
pp. 195-200 ◽  
Author(s):  
A. A. Tsonis ◽  
K. P. Georgakakos

Abstract. Reconstructing the dynamics of nonlinear systems from observations requires the complete knowledge of its state space. In most cases, this is either impossible or at best very difficult. Here, by using a toy model, we investigate the possibility of deriving useful insights about the variability of the system from only a part of the complete state vector. We show that while some of the details of the variability might be lost, other details, especially extreme events, are successfully recovered. We then apply these ideas to the problem of rainfall estimation from satellite imagery. We show that, while reducing the number of observables reduces the correlation between actual and inferred precipitation amounts, good estimates for extreme events are still recoverable.


2015 ◽  
Vol 5 (6) ◽  
pp. 20150049 ◽  
Author(s):  
Jennifer F. Hoyal Cuthill

Biological variety and major evolutionary transitions suggest that the space of possible morphologies may have varied among lineages and through time. However, most models of phylogenetic character evolution assume that the potential state space is finite. Here, I explore what the morphological state space might be like, by analysing trends in homoplasy (repeated derivation of the same character state). Analyses of ten published character matrices are compared against computer simulations with different state space models: infinite states, finite states, ordered states and an ‘inertial' model, simulating phylogenetic constraints. Of these, only the infinite states model results in evolution without homoplasy, a prediction which is not generally met by real phylogenies. Many authors have interpreted the ubiquity of homoplasy as evidence that the number of evolutionary alternatives is finite. However, homoplasy is also predicted by phylogenetic constraints on the morphological distance that can be traversed between ancestor and descendent. Phylogenetic rarefaction (sub-sampling) shows that finite and inertial state spaces do produce contrasting trends in the distribution of homoplasy. Two clades show trends characteristic of phylogenetic inertia, with decreasing homoplasy (increasing consistency index) as we sub-sample more distantly related taxa. One clade shows increasing homoplasy, suggesting exhaustion of finite states. Different clades may, therefore, show different patterns of character evolution. However, when parsimony uninformative characters are excluded (which may occur without documentation in cladistic studies), it may no longer be possible to distinguish inertial and finite state spaces. Interestingly, inertial models predict that homoplasy should be clustered among comparatively close relatives (parallel evolution), whereas finite state models do not. If morphological evolution is often inertial in nature, then homoplasy (false homology) may primarily occur between close relatives, perhaps being replaced by functional analogy at higher taxonomic scales.


2020 ◽  
Author(s):  
Ziqiao Yin ◽  
Binghui Guo ◽  
Shuangge Steven Ma ◽  
Yifan Sun ◽  
Zhilong Mi ◽  
...  

AbstractResearches on dynamical features of biological systems are mostly based on fixed network structure. However, both biological factors and data factors can cause structural perturbations to biological regulatory networks. There are researches focus on the influence of such structural perturbations to the systems’ dynamical features. Reachability is one of the most important dynamical features, which describe whether a state can automatically evolve into another state. However, there is still no method can quantitively describe the reachability differences of two state spaces caused by structural perturbations. DReSS, Difference based on Reachability between State Spaces, is proposed in this research to solve this problem. First, basic properties of DReSS such as non-negativity, symmetry and subadditivity are proved based on the definition. And two more indexes, diagDReSS and iDReSS are proposed based on the definition of DReSS. Second, typical examples like DReSS = 0 or 1 are shown to explain the meaning of DReSS family, and the differences between DReSS and traditional graph distance are shown based on the calculation steps of DReSS. Finally, differences of DReSS distribution between real biological regulatory network and random networks are compared. Multiple interaction positions in real biological regulatory network show significant different DReSS value with those in random networks while none of them show significant different diagDReSS value, which illustrates that the structural perturbations tend to affect reachability inside and between attractor basins rather than to affect attractor set itself.Author summaryBoolean network is a kind of networks which is widely used to model biological regulatory systems. There are structural perturbations in biological systems based on both biological factors and data-related factors. We propose a measurement called DReSS to describe the difference between state spaces of Boolean networks, which can be used to evaluate the influence of specific structural perturbations of a network to its state space quantitively. We can use DReSS to detect the sensitive interactions in a regulatory network, where structural perturbations can influence its state space significantly. We proved properties of DReSS including non-negativity, symmetry and subadditivity, and gave examples to explain the meaning of some special DReSS values. Finally, we present an example of using DReSS to detect sensitive vertexes in yeast cell cycle regulatory network. DReSS can provide a new perspective on how different interactions affect the state space of a specific regulatory network differently.


Author(s):  
S. Goncharevskyi ◽  
M. Makarchuk ◽  
V. Martynyuk

Almost all processes in the human body in one way or another connected with the autonomic nervous system. That's why it is real to evaluate the functional state of the person by temperature characteristics of representative points of the autonomic nervous system. Location and information of these points are confirmed by fundamental research. However, simply measuring the temperature at some points may not be sufficient to establish any systematic changes in the human body. The establishment of such changes requires systematic assessment of interdependent significant relationships between these parameters.The main aim of our research was to study effects of myocardial infarction in the thoracic region of the autonomic nervous system. The temperature of representative areas of the thoracic autonomic nervous system we measured by infrared thermometer (Medisana FTO D-53340 , with an accuracy of 0.1 degree Celsius). Statistical analysis was conducted in the packet Statistics 10. The presence of a difference in the temperature coefficients of representative areas (p<0,05). For the left side of the spine characterized by a difference in Th1–Th5 segments, which confirms their diagnosis: Th1 – 0,931,12 (control) and -0,797,49 (experiment), Th2 – 1,571,12 and -0,486,70, Th3 – 1,582611,12325 and -0,663,36, Th4 – 0,85913 0,92611 and -1,74,64, Th5 – 0,923480,75469 and-1,615,73 respectively. For the right side of the thoracic spines: Th6 – 0,850,73 (control) and -0,797,49 (experiment), Th7 – -1,000,79 and -1,370,69, Th8 – -0,960,73 and -0,990,68, Th9 – -0,120,64 and -0,380,83, Th10 – -0,921,14 and -1,031,00, Th11 – -1,691,05 and -1,861,06, Th12- -1,651,15 and -1,961,12 respectively. We found that myocardial infarction is manifested in the thoracic spine. In an experimental group there is significant difference of temperature in all segments. We can also notice asymmetry of temperatue between the right and left side of the spine. In the test group there are a deviation from the normal temperature in the first five thoracic segments on the left side, which confirms their diagnosis. On the right side of the spine there are a deviation in the last seven segments, which may indicate the compensatory mechanisms of regulation of the system. We can observe the temperature asymmetry, which in long-term exposure can negatively affect to the body.


2020 ◽  
Author(s):  
D. Jones ◽  
V. Lowe ◽  
J. Graff-Radford ◽  
H. Botha ◽  
D. Wiepert ◽  
...  

AbstractDisruption of mental functions in Alzheimer’s disease (AD) and related disorders is accompanied by selective degeneration of brain regions for unknown reasons. These regions comprise large-scale ensembles of cells organized into networks required for mental functioning. A mechanistic framework does not exist to explain the relationship between clinical symptoms of dementia, patterns of neurodegeneration, and the functional connectome. The association between dementia symptoms and degenerative brain anatomy encodes a mapping between mental functions and neuroanatomy. We isolated this mapping through unsupervised decoding of neurodegeneration in humans. This reflected a simple information processing-based functional description of macroscale brain anatomy, the global functional state space (GFSS). We then linked the GFSS to AD physiology, functional networks, and mental abilities. We extended the GFSS framework to normal aging and seven degenerative diseases of mental functions.One Sentence SummaryA global information processing framework for mental functions links neuroanatomy, cognitive neuroscience and clinical neurology.


2020 ◽  
Author(s):  
Andy E Williams

Any system with repeatable behavior can potentially be defined with the minimal set of functions that might be composed to represent the entirety of that behavior. The states accessible through these functions then forms a “functional state space” through which the system moves. Since functional states spaces can be used to represent every problem domain from physics, to communications, to business operations, to the human cognition itself, a general approach to not only research but design and all other processes of discovery that is applicable to all domains can potentially be defined to radically increase capacity for discovery in each domain.


2011 ◽  
Vol 02 (02) ◽  
pp. 79-81 ◽  
Author(s):  
Michail Yurevich Dolomatov ◽  
Nikolay Vasilevich Kalashchenko ◽  
Sergei Vladislavovich Dezortsev ◽  
Timur Ramilevich Araslanov

1997 ◽  
Vol 26 (524) ◽  
Author(s):  
Søren Christensen ◽  
Laure Petrucci

<p>State Space Analysis is one of the most developed analysis methods for Petri Nets. The main problem of state space analysis is the size of the state spaces. Several ways to reduce it have been proposed but cannot yet handle industrial size systems.</p><p>Large models often consist of a set of modules. Local properties of each module can be checked separately, before checking the validity of the entire system. We want to avoid the construction of a single state space of the entire system.</p><p>When considering transition sharing, the behaviour of the total system can be capture by the state spaces of modules combined with a Synchronisation Graph. To verify that we do not lose information we show how the full state space can be conctructed.</p><p>We show how it is possible to determine usual Petri Nets properites, without unfolding to the ordinary state space.</p>


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