Unsaturated Fatty Acids of Blood Serum from Pigs with and without Parakeratosis.

In the test tube, sodium linoleate and sodium linolenate kill and dissolve virulent pneumococci more rapidly and in higher dilutions than sodium oleate; otherwise their action is the same. The intensity of action on the cocci is directly proportional to the degree of unsaturation of the acid. Blood serum inhibits the bacteriolytic and hemolytic action of unsaturated soaps partially or completely, according to definitive quantitative relations between serum and soap. Small quantities of serum completely inhibit the action of dilute soap solutions, but even whole serum does not prevent bacteriolysis and hemolysis by relatively concentrated soap solutions, i. e. 1 per cent. and 0.5 per cent. A given quantity of serum inhibits the action of the soaps in inverse ratio to their degree of unsaturation. The hemolytic and bacteriolytic action of soaps of the unsaturated fatty acids is probably due in part to their avidity for protein and not wholly to their ability to dissolve lipoids. Attempts to prevent serum inhibition of the lytic action of sodium linoleate and sodium linolenate were unsuccessful. The more unsaturated soaps are not as efficient in preventing fatal pneumococcic infection of animals as sodium oleate.

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The effect of frequency of supplementing rumen-protected unsaturated fatty acids on blood serum fatty acid profiles in beef heifers and lactating cows

Journal of Animal Science ◽

10.2527/jas2016.1275 ◽

2017 ◽

Vol 95 (7) ◽

pp. 2977

Author(s):

E. K. Cook ◽

M. E. Garcia-Ascolani ◽

R. E. Ricks ◽

S. K. Duckett ◽

G. C. Lamb ◽

...

Keyword(s):

Fatty Acids ◽

Fatty Acid ◽

Blood Serum ◽

Unsaturated Fatty Acids ◽

Fatty Acid Profiles ◽

Beef Heifers ◽

Serum Fatty Acid ◽

Lactating Cows

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Carcass traits, blood serum and meat lipid fractions in Polish Landrace pigs differing in RYR1 genotype

Biotechnology in Animal Husbandry ◽

10.2298/bah0502041j ◽

2005 ◽

Vol 21 (1-2) ◽

pp. 41-48

Author(s):

A. Janik ◽

T. Barowicz ◽

M. Pieszka ◽

W. Migdai

Keyword(s):

Fatty Acids ◽

Blood Serum ◽

Ldl Cholesterol ◽

Unsaturated Fatty Acids ◽

Saturated Fatty Acids ◽

Carcass Traits ◽

Intramuscular Fat ◽

Lower Amount ◽

Longissimus Dorsi ◽

Lipid Fractions

The aim of study was to investigate the effect of RYR1 genotypes on carcass traits and lipid fractions in blood serum and musculus longissimus dorsi of Polish Landrace pigs. The fatteners with RYR1CRYR1 genotype had lower level of triglycerides, total cholesterol, HDL- and LDL cholesterol in blood serum than individuals from RYR1CRYR1C group. The same group of animals had lower amount of intramuscular fat and cholesterol in comparison to homozygotes RYR1CRYR1C. The intramuscular fat of heterozygotes contained less saturated fatty acids, but more unsaturated fatty acids including polyunsaturated acids. The RYR1 genotype had no significant effect on all studied traits in Polish Landrace fatteners.

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W10.268 Unsaturated fatty acids modulate ABCA1 gene expression in human THP-1 macrophages

Atherosclerosis ◽

10.1016/s0021-9150(04)90267-5 ◽

2004 ◽

Vol 5 (1) ◽

pp. 62

Author(s):

J VALLVE

Keyword(s):

Gene Expression ◽

Fatty Acids ◽

Unsaturated Fatty Acids ◽

Abca1 Gene

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DEVELOPMENT OF AN EXPERIMENTAL MODEL OF AVITAMINOSIS F

Grain Products and Mixed Fodder’s ◽

10.15673/gpmf.v20i2.1764 ◽

2020 ◽

Vol 20 (2) ◽

pp. 38-40

Author(s):

A. Levitsky ◽

A. Lapinska ◽

I. Selivanskaya

Keyword(s):

Fatty Acids ◽

Experimental Model ◽

Unsaturated Fatty Acids ◽

Saturated Fatty Acids ◽

Coconut Oil ◽

The Body ◽

Regulatory Function ◽

Omega 3 ◽

White Rats ◽

Arachidonic Acids

The article analyzes the role of essential polyunsaturated fatty acids (PUFA), especially omega-3 series in humans and animals. The biosynthesis of essential PUFA in humans and animals is very limited, so they must be consumed with food (feed). Тhe ratio of omega-3 and omega-6 PUFA is very important. Biomembranes of animal cells contain about 30% PUFA with a ratio of ω-6/ ω-3 1-2. As this ratio increases, the physicochemical properties of biomembranes and the functional activity of their receptors change. The regulatory function of essential PUFA is that in the body under the action of oxygenase enzymes (cyclooxygenase, lipoxygenase) are formed extremely active hormone-like substances (eicosanoids and docosanoids), which affect a number of physiological processes: inflammation, immunity, metabolism. Moreover, ω-6 PUFA form eicosanoids, which have pro-inflammatory, immunosuppressive properties, and ω-3 PUFAs form eicosanoids and docosanoids, which have anti-inflammatory and immunostimulatory properties. Deficiency of essential PUFA, and especially ω-3 PUFA, leads to impaired development of the body and its state of health, which are manifestations of avitaminosis F. Prevention and treatment of avitaminosis F is carried out with drugs that contain PUFA. To create new, more effective vitamin F preparations, it is necessary to reproduce the model of vitamin F deficiency. An experimental model of vitamin F deficiency in white rats kept on a fat –free diet with the addition of coconut oil, which is almost completely free of unsaturated fatty acids, and saturated fatty acids make up almost 99 % of all fatty acids was developed. The total content of ω-6 PUFA (sum of linoleic and arachidonic acids), the content of ω-3 PUFA (α-linolenic, eicosapentaenoic and docosahexaenoic acids) in neutral lipids (triglycerides and cholesterol esters) defined. Тhe content of ω-6 PUFA under the influence of coconut oil decreased by 3.3 times, and the content of ω-3 PUFA - by 7.5 times. Тhe influence of coconut oil, the content of ω-6 PUFA decreased by 2.1 times, and the content of ω-3 PUFA - by 2.8 times. The most strongly reduces the content of ω-3 PUFA, namely eicosapentaenoic, coconut oil, starting from 5 %. Consumption of FFD with a content of 15 % coconut oil reduces the content of eicosapentaenoic acid to zero, ie we have an absolute deficiency of one of the most important essential PUFAs, which determined the presence of vitamin F deficiency.

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Dietary pattern analysis reveals key food groups contributing to the successful exchange of saturated with unsaturated fatty acids in healthy men.

10.26226/morressier.5ef37080b2a27f760262bb58 ◽

2020 ◽

Author(s):

Laury Sellem

Keyword(s):

Fatty Acids ◽

Dietary Pattern ◽

Pattern Analysis ◽

Unsaturated Fatty Acids ◽

Food Groups ◽

Healthy Men ◽

Dietary Pattern Analysis

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PHYTOCHEMICAL SCREENING, ANTIOXIDANT, ANTI-CYTOTOXIC AND ANTICANCER EFFECTS OF GALINSOGA PARVIFLORA AND VERNONIA POLYANTHES (ASTERACEAE) EXTRACTS

International Journal of Research -GRANTHAALAYAH ◽

10.29121/granthaalayah.v8.i10.2020.1782 ◽

2020 ◽

Vol 8 (10) ◽

pp. 84-98

Author(s):

Sula M. V. Feleti ◽

Renê L. Aleluia ◽

Suiany V. Gervásio ◽

Jean Carlos V. Dutra ◽

Jessica R. P. Oliveira ◽

...

Keyword(s):

Fatty Acids ◽

Phenolic Acids ◽

Unsaturated Fatty Acids ◽

Biological Effects ◽

Human Lymphocytes ◽

Chemical Characterization ◽

Total Content ◽

Ags Cells ◽

Ft Icr Ms ◽

Ft Icr

The study was designed to investigate the chemical composition and the biological effects of G. parviflora and V. polyanthes ethanolic extracts in vitro. Total content of phenols, flavonoids and tannins was quantified by spectrophotometry; chemical characterization was permed by mass spectrometry (ESI (-) FT-ICR MS and APCI (+) FT-ICR MS analysis). Antioxidant activities were determined by FRAP and Fe2+ chelating methods. Extracts cytotoxicity was evaluated in human lymphocytes, sarcoma-180 (S-180) and human gastric adenocarcinoma (AGS) cells, by MTT assay. V. polyanthes presented higher total content of tannins and G. parviflora presented higher amount of phenols and flavonoids. Chemical characterization showed the presence of flavonoids, phenolic acids and sesquiterpene lactones in V. polyanthes extract, and steroids, phenolic acids and fatty acids (Poly Unsaturated Fatty Acids - PUFA) in G. parviflora extract. V. polyanthes extract stood out in the Fe2+ chelation test. G. parviflora extract did not present outstanding antioxidant results in the tested protocols. Both species showed a tendency to promote cytotoxicity in human lymphocyte cells. Regarding the antiproliferative effect, both species were able to reduce S-180 cell viability and G. parviflora extract showed high antiproliferative potential in the assay with AGS cells. These findings reinforce the medicinal use of these plants, as well as suggest their potential use for the development of new drugs and for the treatment of cancers.

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