scholarly journals Primitive Mesenchymal Stroma Formation

2020 ◽  
Author(s):  
Keyword(s):  
Mesenchymal Stroma

scholarly journals Intrahepatic biliary cystadenomas with and without mesenchymal stroma

HPB ◽  
1999 ◽  
Vol 1 (3) ◽  
pp. 141-146 ◽  
Author(s):  
W. Davies ◽  
L. Weiland ◽  
K. Batts ◽  
D.M. Nagorney
Keyword(s):  
Mesenchymal Stroma

scholarly journals Mesenchymal stroma cells in peritoneal dialysis effluents from patients

Human Cell ◽  
2017 ◽  
Vol 30 (2) ◽  
pp. 51-59 ◽  
Author(s):  
Bin Liu ◽  
Qiunong Guan ◽  
Jing Li ◽  
Gerald da Roza ◽  
Hao Wang ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Mesenchymal Stroma ◽  
Mesenchymal Stroma Cells

Mesenchymal stroma: Role in osteosarcoma progression

2017 ◽  
Vol 405 ◽  
pp. 90-99 ◽  
Author(s):  
Margherita Cortini ◽  
Sofia Avnet ◽  
Nicola Baldini
Keyword(s):  
Mesenchymal Stroma

Oncocytic Biliary Cystadenocarcinoma: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (2) ◽  
pp. e25-e28 ◽  
Author(s):  
Richard L. Bardin ◽  
Jacqueline K. Trupiano ◽  
Russell M. Howerton ◽  
Kim R. Geisinger
Keyword(s):  
Prognostic Significance ◽  
Cytokeratin 20 ◽  
Cytoplasmic Staining ◽  
Female Patients ◽  
Biliary Cystadenocarcinoma ◽  
Granular Cytoplasm ◽  
Mesenchymal Stroma ◽  
The Right ◽  
Papillary Neoplasm ◽  
Granular Cytoplasmic Staining

Abstract We report an unusual case of biliary cystadenocarcinoma with oncocytic differentiation. The patient was a 43-year-old woman who presented with right upper quadrant pain. Imaging revealed a 16 × 10 × 10-cm, heterogenous, right hepatic mass with extension into the right atrium. Surgical resection revealed a papillary neoplasm of malignant cells with atypical hyperchromatic nuclei and prominent nucleoli lining fibrovascular cores. Mesenchymal stroma was not present. The majority of the epithelial cells had abundant eosinophilic granular cytoplasm, consistent with oncocytic differentiation. There was extensive stromal and hepatic parenchymal invasion. Immunohistochemical staining revealed a “biliary pattern” of cytokeratin subset immunoreactivity, with positivity for cytokeratin 7 and an absence of staining with cytokeratin 20. The tumor was negative for mucin, carcinoembryonic antigen, α-fetoprotein, calretinin, CD31, and chromogranin. There was granular cytoplasmic staining with phosphotungstic acid hematoxylin, consistent with the presence of abundant mitochondria. Electron microscopy revealed abundant mitochondria within the neoplastic cells. This case is quite unusual because female patients only rarely lack the characteristic ovarian-like mesenchymal stroma of biliary cystadenomas/cystadenocarcinomas. Furthermore, to our knowledge, oncocytic differentiation in this neoplasm has been reported previously on only 2 occasions. The biologic behavior and prognostic significance, if any, of the lack of mesenchymal stroma in female patients or the presence of oncocytic differentiation remains to be further elucidated as more of these cases are described.

Lymphangioma of the Pancreas With “Ovarian-like” Mesenchymal Stroma: A Case Report With Emphasis on Histogenesis

2003 ◽  
Vol 127 (11) ◽  
pp. 1513-1516 ◽  
Author(s):  
Lizhen Gui ◽  
Steven A. Bigler ◽  
Charu Subramony
Keyword(s):  
Endothelial Cells ◽  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Mesenchymal Cells ◽  
Developmental Anomaly ◽  
Mesenchymal Stroma ◽  
Multiple Cysts ◽  
Lymphoid Aggregates

Abstract Pancreatic lymphangiomas, which occur predominantly in women, are rare and account for only 1% of all lymphangiomas. The characteristic histologic features include multiple cysts lined by endothelial cells, irregularly distributed smooth muscle cells, and lymphoid aggregates in the wall of the cyst. We describe a 36-year-old woman with lymphangioma of the pancreas with “ovarian-like” mesenchymal stroma in the wall. This stroma, composed of uncommitted mesenchymal cells, has not been described previously in the wall of pancreatic lymphangiomas. Multiple small lymphatic channels that are found in this stroma recapitulate the development of lymphatic channels in the embryo. Lymphangioma of the pancreas may arise from distension of these lymphatic channels. Pancreatic lymphangioma may, therefore, be a developmental anomaly rather than a true neoplasm.

scholarly journals Nephroblastoma in a black-tufted marmoset (Callithrix penicillata)

2018 ◽  
Vol 38 (11) ◽  
pp. 2155-2158
Author(s):  
Jair A. Ferreira Junior ◽  
Daniel R. Rissi ◽  
Mônica A. Elias ◽  
André S. Leonardo ◽  
Karla A. Nascimento ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Left Kidney ◽  
Free Living ◽  
Left Ureter ◽  
Central Brazil ◽  
Mesenchymal Stroma ◽  
Nuclear Immunoreactivity ◽  
Embryonic Epithelium ◽  
Friable Mass

ABSTRACT: A renal nephroblastoma is described in a free-living black-tufted marmoset (Callithrix penicillata) in Central Brazil. The monkey was found dead and subjected to necropsy. Gross anatomic changes consisted of a ruptured left kidney, which was almost completely effaced by a white to yellow, partially encapsulated friable mass. The left ureter was distended due to obstruction by a red, spherical, 2mm in diameter friable mass. The urinary bladder was also distended. Histologically the renal and ureteral masses consisted of a triphasic embryonal neoplasm composed of embryonic epithelium forming glomeruli and tubules, polygonal blastemal cells, and a mesenchymal stroma. The embryonic epithelium exhibited rare nuclear immunoreactivity for WT-1, whereas blastemal cells exhibited robust cytoplasmic and rare nuclear immunoreactivity for WT-1; blastemal cells were also immunoreactive for vimentin. No immunoreactivity was detected for pan-cytokeratin (AE1/AE3), actin, and desmin. Morphological and immunohistochemical features of the present neoplasm are consistent with those described for renal nephroblastoma.

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