Risk Factors in Diabetes and Pregnant Women with Urinary Tract Infections Compared to Younger Aged Female.

2018 ◽  
Vol 1 (3) ◽  
pp. 26-38
Author(s):  
Abdulghani Mohamed Alsamarai ◽  
Shler Ali Khorshed

Background: Urinary tract infection is common with health impact in women and characterised by failure to treatment and recurrent episodes. Aim: This study was conducted to determine the risk factors for the development of urinary tract infection in diabetic and pregnant women in comparison to student female. Materials and methods: A prospective cross-sectional study conducted during the period from 1st of June 2015 to the end of January 2016. The population included in the study are 563 women, of them 425 were outpatients, and 138 were inpatients. Their age range between 18 and 80 years, with a mean age of 33.59±15.29 years. Urine samples collected and cultured on blood agar and MacConkey agar by spread plate technique. Bacterial colonies with different morphology were selected, purified and identified according to their biochemical characteristics using conventional standard methods. Results: In diabetic women, there were no significant difference in mean age and BMI values between culture positive and culture negative groups. However, pus cell mean scale was significantly higher [P=0.000] in women with urinary tract infection [1.76±1.25] than in those with negative culture [0.69±1.00]. In pregnant women, BMI mean value was significantly [P=0.013] lower in pregnant women with UTI [26.14] as compared to those without infection [26.99]. Pus cell scale mean value was significantly [P=0.000] higher in pregnant women with UTI [1.55] than women with negative UTI [0.85]. While there was no significant difference in mean age between UTI positive and negative pregnant women. In female student, there was a significant difference between UTI infected and non-infected in mean age [P=0.041] and pus cell scale [P=0.000]. However, BMI was not significantly different between infected and non-infected female student. Other risk factors association are variables in the 3 groups when analysed using X2, while AUC and OR show different trends of association between risk factors and UTI. Conclusion: BMI, pus cell scale, child number, delivery method, operation history and hospital setting were significantly associated with culture positivity in the 3 studied groups as determined by AUC. While OR confirmed association with pus sale scale in the 3 groups.

2021 ◽  
Vol 8 (03) ◽  
pp. 5275-5281
Author(s):  
Faith Diorgu ◽  
Maynard Ehianu ◽  
Anacletus Francis

Associated Risk Factors for Bacterial Urinary Tract Infection among Internally Displaced Pregnant Women in Niger Delta Camps, Nigeria   Abstract This study investigated associated risk factors for bacterial urinary tract infection among internally displaced pregnant women in Niger Delta camps. The objectives of the study were to determine the association between age, parity, trimester of pregnancy, religion and the incidence of bacterial urinary tract infection among internally displaced pregnant women. The population of the study comprised 108 internally displaced pregnant women who also formed the study sample as no sampling method was adopted due to the limited number of study participants. The tools for data collection was midstream urine samples collected using sterile screw-capped universal containers, the instruments used in isolating the bacterial uropathogens, include Cysteine-Lactose Deficient (CLED) agar, MacConkey and Nutrient agar plates as well as a structured checklist in socio-demographic characteristics of the pregnant women. Descriptive statistics of frequency and percentage were used for data analysis and the Statistical Package for Social Sciences (SPSS) software was employed in the analytical process. Results from the study showed there was no significant association between age, parity, trimester of pregnancy, and the incidence of bacterial urinary tract infection among internally displaced pregnant women (P>0.05). However, religion was significantly associated with the incidence of bacterial urinary tract infection among internally displaced pregnant women (P<0.05).  The study concluded that there is an increasing incidence of bacterial urinary tract infections among internally displaced pregnant women linked to religious beliefs.  Based on the study findings, early routine screening of all internally pregnant women presenting or not presenting with clinical symptoms of urinary tract infection is recommended. The need for good personal and environmental hygiene to be encouraged in internally displaced persons’ camps. Keywords: Associated risk factors, Bacterial urinary tract infection, Internally Displaced Women, Camps, Niger Delta    


2020 ◽  
Vol 3 (9) ◽  
pp. 454-458
Author(s):  
Shikha Thakur ◽  
Dr. Komal Lata Nagpal

Background: Urinary tract infections “UTIs” are one of the frequently encountered problems during pregnancy. Untreated UTI can be associated with serious obstetric complications.  Hence the management and prevention of UTI in pregnancy is the crucial factor for the sustained pregnant period. Hence the present study was designed to identify the pathogenic agents of UTI and its associated risk factors in antenatal mothers in two private hospitals at Kathmandu city. Aim: The main objective of the study was to identify the etiological agent and associated risk factor in Urinary tract infection among pregnant women attending the antenatal care service visit in a selected hospital. Study Design: Cross-sectional descriptive study. Place and Time of Study: The study was carried out under the supervision of University and field study was carried out in Kathmandu, Nepal from March 2019 to October 2019. Methods: The cross-sectional study was performed at the Norvic Hospital and Baidya and Banskota hospital from March 2019 to October 2019. In this cross-sectional study, a total of 510, clean catch midstream urine (MSU) samples were collected aseptically and analyzed using standard microbiology methods. Data for the factors associated with UTI were obtained by use of questionnaires and standard laboratory tests for selected underlying conditions concerning associated risk factors were collected using structured questionnaires and the sample was also processed for antimicrobial drug susceptibility testing. Results: The study revealed 193/510(37.84%) UTI prevalence among patients attending two hospitals in Kathmandu valley. Escherichia coli was the most prevalent bacterial uropathogen with 119/193(61.6%) followed by Klebsiella pneumoniae 35/193(18.13%), Staphylococcus aureus 22/193 (11.39%), Proteus mirabilis 7/193 (3.6%), Enterococcus faecalis 2/193 (1.0%), Enterobacter aerogenes2/193(1.0%) Serratia odorifera 3/193(1.5%), Streptococcus species3/193(1.5%). Conclusions: The high prevalence of urinary tract infection in pregnant women warrant the need to screen all pregnant women and treat those infected with appropriate antimicrobial regimens in order to reduce its complications. Urinary Tract Infection screening is essential in pregnant women.


2014 ◽  
Vol 27 (3) ◽  
pp. 364 ◽  
Author(s):  
Ana Bispo ◽  
Milene Fernandes ◽  
Cristina Toscano ◽  
Teresa Marques ◽  
Domingos Machado ◽  
...  

<strong>Introduction:</strong> Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients.<br /><strong>Material and Methods:</strong> This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections.<br /><strong>Results:</strong> A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p &lt; 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p &lt; 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the<br />most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions.<br /><strong>Discussion:</strong> Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated.<br /><strong>Conclusion:</strong> Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions.<br /><strong>Keywords:</strong> Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.


2021 ◽  
Vol 21 (1) ◽  
pp. 214-9
Author(s):  
Ertugrul Guclu ◽  
Fikret Halis ◽  
Elif Kose ◽  
Aziz Ogutlu ◽  
Oğuz Karabay

Background: Urinary tract infections (UTIs) are one of the most seen infection among community. Objectives: In this cross-sectional study we aimed to investigate the risk factors of multidrug-resistant (MDR) bacteria that caused community-acquired UTI (CA-UTI). Methods: Consecutive patients admitted to the Urology and Infectious Diseases policlinics with the diagnosis of CA-UTI were included in the study. A standard form including possible predisposing factors for MDR bacteria was applied. Results: In total, 240 patients (51.3% females) were enrolled in the study. The mean age of participants were 59.8 ± 18.3 years old. Escherichia coli (n =166; 69.2%)was the most frequently isolated bacteria and its incidence was higher in females than in males (p=0.01). In total, 129 (53.8%) of the identified pathogens were MDR bacteria. According to multivariate analysis, the use of antibiotics three or more times increased the risk of infection with MDR bacteria by 4.6 times, the history of urinary tract infection in the last 6 months by 2 times, being male and over 65 years old by 3 times. Conclusion: Doctors should consider prescribing broad-spectrum antibiotics in patients with severe UTIs with a history of UTI, advanced age, male gender, and multiple antibiotic usage, even if they have a CA-UTI. Keywords: Urinary tract infection; community acquired; multidrug-resistant; male; multiple antibiotic usage; advanced age.


2018 ◽  
Vol 5 (3) ◽  
pp. 3577-3579
Author(s):  
Dr. Vishal Mishra ◽  
Dr. Alok Pratap Singh ◽  
Dr. Lal Mani Singh

Introduction : Urinary tract infection is a common contagion among men and women but incidence is quite high among women due to their anatomy. The incidence of the infection is higher among sexually active women and the possibilities of encountering the infection after a sexual intercourse is higher. Identified risk factors for such infections include sexual activity, spermicide-based contraception, delayed postcoital micturition, and a history of previous UTIs. OBJECTIVES : To assess socio demographic factors among patients of urinary tract infection. To assess risk factors contributing to urinary tract infection. Material and methods : Total 91 female patients, who were diagnosed to have urinary tract infection were selected in our study. Data regarding socio-demographic and various risk factors was collected and frequency distribution tables were prepared. RESULTS : Majority females (68%) were between 18-45 years old. About 64% patients belonged to rural area, and 90% patients belong to lower, or lower middle class. About 68% patient’s education was below high school and about 74% patients were married. Among risk factors for UTI, we found that sexual activity (in 83%) was most common risk factor for UTI. CONCLUSION: Patient who are exposed to risk factors, should be given special attention by the visiting clinicians, so that early diagnosis can be made and early treatment can be started. Early diagnosis and treatment leads to less complications, morbidities and mortality. 


1981 ◽  
Vol 15 (11) ◽  
pp. 863-866
Author(s):  
Randall A. Prince ◽  
Deborah H. Cassel ◽  
Charles D. Hepler ◽  
James L. Wilson ◽  
Mark E. Jones ◽  
...  

Traditionally, the therapeutic regimen of sulfisoxazole in acute urinary tract infection has included either a 2- or 4-g loading dose. However, the biopharmaceutical aspects of this drug indicate that a loading dose is unnecessary. The objective of this clinical study, therefore, was to compare a traditional regimen of sulfisoxazole to a regimen not utilizing a loading dose. Fifty adult female patients with acute, uncomplicated urinary tract infections were assigned to a ten-day course of sulfisoxazole 1 g po qid. Patients were randomly allocated to a 2-g loading dose or no loading dose regimen. Data were analyzed with regard to resolution of presenting symptoms and eradication of the infecting organism (i.e., cure). Statistical analysis demonstrated no significant difference for symptom resolution and cure. It appears that the convention of using an initial 2-g oral loading dose of sulfisoxazole in the treatment of acute, uncomplicated urinary tract infection is unwarranted.


Author(s):  
Bhavana Ashish Kakaria ◽  
Ashish K. ◽  
Raghuwanshi Tushar

Background: Catheter-associated urinary tract infections (CAUTIs) are the most common nosocomial infection and a leading cause of morbidity and mortality in hospitalized patients. The aim of this study was to determine the incidence and risk factors of urinary tract infection in catheterised patients in a tertiary care hospital.Methods: Total of 200 patients above 16 years in whom an indwelling Foley‘s catheter inserted were taken in the study. A urine specimen was obtained aseptically and culture done on nutrient agar, sheep blood agar and MacConkey agar plates. After incubation of 24 hours, colony count done for organisms showing growth and colony count ≥105 was taken significant.Results: The incidence of CAUTI in the present study was 31%. Higher incidence of CAUTI (56.46%) was found in female sex as compared to males (43.54%). Incidence of CAUTI was found higher in first weeks (54.83%). Incidence among diabetes patients is found more (63.33%). Most common isolate found was E. coli (38.71%) among all uropathogens. Uropathogens isolated from CAUTI are more resistant to antimicrobials.Conclusions: It is must to implement following strategy for reducing the risk of infection due to indwelling catheters: 1. reducing the duration of catheterization 2. Use antibacterial substance coated catheter 3. Strict infection control measures.


2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Mohamed Radwan ◽  
Ayman Hagras ◽  
Salah Nagla ◽  
Nareman Elhamamy ◽  
Mohammed Abou Farha

Abstract Background Fosfomycin tromethamine is recommended (category B) for the treatment of urinary tract infections in pregnant women. We aimed to evaluate the efficacy of single-dose preoperative fosfomycin tromethamine in the prevention of urinary tract infection in pregnant women who underwent lower urinary tract endoscopic surgeries. Methodology The subjects of this study were pregnant women who underwent lower urinary tract endoscopic procedures. All patients received Fosfomycin tromethamine1 packet (3 g) dissolved in water the day before surgery. Routine pre- and postoperative urine analysis and urine cultures were performed when needed. Patients were monitored for urinary tract infections and the side effects of the drug. Moreover, maternal and fetal complications were monitored. Results The study was conducted on 31 pregnant women with a mean age of 24.48 ± 5.35 years. The endoscopic procedures were as follows: 28 (90.3%) DJ ureteric insertions for hydronephrosis, 2 (6.5%) urinary bladder stones, and cystoscopy (3.2%) for gross hematuria. Two (6.5%) patients had postoperative asymptomatic bacteriuria that resolved with oral antibiotic therapy. Conclusion Fosfomycin tromethamine is safe in preventing urinary tract infection and decreases the need for postoperative parenteral antibiotics in pregnant women who require lower urinary tract endoscopic procedures.


2018 ◽  
Vol 11 (1) ◽  
pp. 19
Author(s):  
Edy Fakhrizal

To obtain a prevalence of urinary tract infection in pregnancy andits influential risk factors.This is a cross sectionalstudy. The subjects were all pregnant women who came to Obstetric & Gynecology clinic of Arifin Achmad Pekanbaru– Riau Hospital, between June 1st and October 31st 2016. Subjects with appropriate inclusion and exclusion criteriaand agreed to join this study were asked to fill out questionnaire and urinalysis test was done.The data was analyzedwith Stata 12. The distribution of data was analyzed with descriptive univariate and presented in (n) and(%). Bivariateanalysis was done to see any influential risk factors to urinary tract infection in pregnancy. From recruited 74 subjects,27subjects (36,5%) were with urinary tract infection and 4 subject of its (14,8%) was asymptomatic bacteriuria. Theprevalence of urinary tract infection in pregnancy in this study was 36,5% and the influential risk factors wereeducation, occupation, total water consumpted a day, and cleaning vagina before coitus.


Author(s):  
Srinath M. P. ◽  
Shajina M. ◽  
Fasalu Rahiman O. M.

Background: Infectious disease such as urinary tract infection was found very commonly during all pregnancies. Chronic renal failure, pyelonephritis, preeclampsia, anemia, fetal mortality and premature delivery are the common complication associated with UTI in pregnancy. Hence the management and prevention of UTI in pregnancy is the crucial factor for the sustained pregnant period. It is more important for a clinician to recognize the pathogenic factor for UTI and its sensitivity profile for planning an effective treatment for infected patients. Hence the present study was designed to identify the pathogenic agents of UTI among pregnant women and to find out the drug susceptibility patterns of the isolated organism against commonly prescribed antibioticsMethods: A prospective analysis was carried out by collecting urine from the 210 patients, the sample was also processed for antimicrobial drug susceptibility testing.Results: A positive report was seen in 26 cases with 13.4% of incident rate. Escherichia coli 14 (53.8%), Klebsiella species 23.07%, Enterococcus species 7.69%, Staphylococcus aureus 3.84%, Proteus 3.84%, Pseudomonas aeroginosa 3.84%, Streptococcus pyogenes 3.84% were the most common isolate found in the present population. The isolated pathogens were sensitive to Ceftazidime, Cefotaxime, Ciprofloxacin, Gentamicin, and Amikacin.Conclusions: It is there for recommended that routine microbiological analysis and antibiotic sensitivity test of urine samples of pregnant women must be carried out before the administration of drugs for better treatments and managements of urinary tract infection.


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