scholarly journals Misdiagnosed Celiac Disease:

2017 ◽  
Vol 7 (1) ◽  
pp. 43-46
Author(s):  
Abdulrahman M. Alahdal
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Case Report ◽  
Male Patient ◽  
Duodenal Biopsy ◽  
Gluten Free ◽  
Serological Testing ◽  
Intestinal Symptoms ◽  
Irritable Bowel ◽  
Saudi Male

The advancement of technologies including the availability of sensitive and specific serological screenings and endoscopic intestinal examinations has led to increased awareness and recognition of silent epidemic celiac disease in patients with irritable bowel syndrome in the last two decades. The objective of this case report is to describe the importance of routine screening of celiac disease in patients with non-specific (common) intestinal symptoms, particularly those with irritable bowel syndrome. The author reported the clinical progress of a 44-year-old Saudi male patient presented with non-specific intestinal symptoms initially misdiagnosed with irritable bowel syndrome. The investigations, including serological testing and endoscopic duodenal biopsy, revealed that the patient had celiac disease. After a course of gluten-free diet, his intestinal symptoms significantly improved. This case report emphasizes the importance of thorough investigations for patients with irritable bowel syndrome to exclude celiac disease.

scholarly journals Celiac disease, rare symptoms, autoimmune patology

2008 ◽  
Vol 2 (1) ◽  
pp. 17-24
Author(s):  
Umberto Volta ◽  
Claudia Parisi ◽  
Maria Piscaglia ◽  
Angela Fabbri ◽  
Erica Fiorini
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Case Report ◽  
Iron Deficiency ◽  
Correct Diagnosis ◽  
Deficiency Anemia ◽  
Gluten Free ◽  
Beneficial Effects ◽  
Intestinal Infections ◽  
Irritable Bowel

We report a case of a 42-years-old woman with constipation, anemia and recurrent itch. After several investigations, celiac disease was diagnosed and a treatment with a gluten-free diet was applied with beneficial effects. Recognizing celiac disease can be difficult because some of its symptoms are similar to those of other diseases. In fact, sometimes it is confused with irritable bowel syndrome or iron-deficiency anemia or intestinal infections: as a result, celiac disease is commonly underdiagnosed or misdiagnosed. This case report is described to address the physician to a correct diagnosis of celiac disease.

scholarly journals Irritable Bowel Syndrome and Gluten-Related Disorders

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1117 ◽  
Author(s):  
Paolo Usai-Satta ◽  
Gabrio Bassotti ◽  
Massimo Bellini ◽  
Francesco Oppia ◽  
Mariantonia Lai ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
The Other ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Gut Permeability ◽  
Online Search ◽  
Systematic Screening ◽  
Wheat Sensitivity ◽  
Irritable Bowel

Background: Irritable bowel syndrome (IBS) is frequently associated with celiac disease (CD) and nonceliac gluten/wheat sensitivity (NCGS/NCWS), but epidemiological and pathophysiological aspects are still unclear. Furthermore, a gluten-free diet (GFD) can positively influence IBS symptoms. Methods: A comprehensive online search for IBS related to CD, NCGS and GFD was made using the Pubmed, Medline and Cochrane databases. Results: Although a systematic screening for CD in IBS is not recommended, CD prevalence can be increased in diarrhea-predominant IBS patients. On the other hand, IBS symptoms can be persistent in treated CD patients, and their prevalence tends to decrease on a GFD. IBS symptoms may overlap and be similar to those associated to nonceliac gluten and/or wheat sensitivity. Increased gut permeability could explain the gluten/wheat effects in IBS patients. Finally, a GFD could improve symptoms in a subgroup of IBS patients. Conclusions: The possible interplay between IBS and gluten-related disorders represents a scientifically and clinically challenging issue. Further studies are needed to confirm these data and better clarify the involved pathophysiological mechanisms.

scholarly journals Gluten-Associated Pathology: Focusing on Patients with Irritable Bowel Syndrome

2020 ◽  
Vol 16 (30) ◽  
pp. 66-73
Author(s):  
O.V. Gaus ◽  
◽  
M.A. Livzan ◽  
D.V. Popello
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Clinical Symptoms ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Wheat Allergy ◽  
The World ◽  
Wheat Products ◽  
Irritable Bowel ◽  
The Many

Wheat is an essential part of the diet of many people around the world. Despite the many beneficial aspects of eating wheat products, they can be associated with the development of a variety of diseases. The spectrum of gluten-associated pathologies includes celiac disease, wheat allergy, and non-celiac gluten sensitivity (NCGS). The clinical symptoms of gluten-associated pathology are similar to those of irritable bowel syndrome (IBS). Diagnosis of celiac disease and wheat allergy is now straightforward. NCGS remains a diagnosis of exclusion due to the lack of specific biomarkers and standardized research methods. Many patients with IBS consider themselves gluten-sensitive and their symptoms are relieved by a gluten-free diet. Most likely it is NCGS that occurs in a heterogeneous group of patients with IBS. However it remains controversial whether the development of symptoms in this case is associated with gluten itself or with other components of wheat, such as non-gluten proteins and FODMAPs.

scholarly journals AMAJA GRAHANI / IRRITABLE BOWEL SYNDROME – A CASE REPORT

2020 ◽  
Vol 04 (04) ◽  
pp. 2363-2366
Author(s):  
Sreeja Sreekumar ◽  
Ravi Varma Raja H
Keyword(s):  
Irritable Bowel Syndrome ◽  
Case Report ◽  
Male Patient ◽  
Alimentary Tract ◽  
Structural Abnormality ◽  
Irritable Bowel

Irritable bowel syndrome (IBS) is a disease of the alimentary tract. Rather than a structural abnormality, it is a disorder of the bowel where the function is altered. Grahani Dosha is a disease mentioned in the ayurvedic scriptures. It has been named so because it is a disorder that alters the function of the bowel as in IBS rather than producing a structural abnormality. In this case study, a 32-year-old male patient presenting with symptoms of IBS was treated with the principle of grahani Dosha. Shamana Chikitsa was done with internal medications for a period of 4 consecutive months. The symptoms of the patient were analysed throughout the period to obtain the findings. Treatment with medications such as Sootasekhara rasa and Dadimashtaka Choorna provided significant relief. Keywords: Irritable bowel syndrome, Grahani Dosha

scholarly journals The Prevalence of Anti-Zein Antibodies: A Comparative Study between Celiac Disease and Irritable Bowel Syndrome

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 649
Author(s):  
Luis Alberto Sánchez-Vargas ◽  
Karina Guadalupe Hernández-Flores ◽  
Francisco Javier Cabrera-Jorge ◽  
José María Remes-Troche ◽  
Job Reyes-Huerta ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Gastrointestinal Disorder ◽  
Newly Diagnosed ◽  
Disease Group ◽  
Immune Mediated ◽  
Healthy Control ◽  
Gliadin Peptides ◽  
Irritable Bowel ◽  
First Time

Celiac disease (CD) is a chronic immune-mediated enteropathy triggered by exposure to dietary gluten in genetically predisposed individuals. In contrast, irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder affecting the large intestine, without an autoimmune component. Here, we evaluated the prevalence of IgA and IgG antibodies to maize zeins (AZA) in patients with CD and IBS. Using an in-house ELISA assay, the IgA and IgG anti-zein antibodies in the serum of 37 newly diagnosed CD (16 biopsy proved and 21 serological diagnosis) and 375 IBS patients or 302 healthy control (HC) subjects were measured. Elevated levels of IgA AZA were found in CD patients compared with IBS patients (p < 0.01) and HC (p < 0.05). CD patients had the highest prevalence (35.1%), followed by IBS (4.3%) and HCs (2.3%) (p < 0.0001). IgG AZA antibodies were not found in any CD patients, IBS patients, or HC subjects. A significant positive correlation was found between IgA AZA with IgA anti-gliadin (AGA, r = 0.34, p < 0.01) and IgA anti-deaminated gliadin peptides (DGP, r = 0.42, p < 0.001) in the celiac disease group. Taken together, our results show for the first time a higher prevalence of AZA IgA antibodies in newly diagnosed CD patients than in IBS patients, confirming a biased immune response to other gliadin-related prolamins such as maize zeins in genetically susceptible individuals.

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