scholarly journals Celiac disease, rare symptoms, autoimmune patology

2008 ◽  
Vol 2 (1) ◽  
pp. 17-24
Author(s):  
Umberto Volta ◽  
Claudia Parisi ◽  
Maria Piscaglia ◽  
Angela Fabbri ◽  
Erica Fiorini
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Case Report ◽  
Iron Deficiency ◽  
Correct Diagnosis ◽  
Deficiency Anemia ◽  
Gluten Free ◽  
Beneficial Effects ◽  
Intestinal Infections ◽  
Irritable Bowel

We report a case of a 42-years-old woman with constipation, anemia and recurrent itch. After several investigations, celiac disease was diagnosed and a treatment with a gluten-free diet was applied with beneficial effects. Recognizing celiac disease can be difficult because some of its symptoms are similar to those of other diseases. In fact, sometimes it is confused with irritable bowel syndrome or iron-deficiency anemia or intestinal infections: as a result, celiac disease is commonly underdiagnosed or misdiagnosed. This case report is described to address the physician to a correct diagnosis of celiac disease.

scholarly journals Misdiagnosed Celiac Disease:

2017 ◽  
Vol 7 (1) ◽  
pp. 43-46
Author(s):  
Abdulrahman M. Alahdal
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Case Report ◽  
Male Patient ◽  
Duodenal Biopsy ◽  
Gluten Free ◽  
Serological Testing ◽  
Intestinal Symptoms ◽  
Irritable Bowel ◽  
Saudi Male

The advancement of technologies including the availability of sensitive and specific serological screenings and endoscopic intestinal examinations has led to increased awareness and recognition of silent epidemic celiac disease in patients with irritable bowel syndrome in the last two decades. The objective of this case report is to describe the importance of routine screening of celiac disease in patients with non-specific (common) intestinal symptoms, particularly those with irritable bowel syndrome. The author reported the clinical progress of a 44-year-old Saudi male patient presented with non-specific intestinal symptoms initially misdiagnosed with irritable bowel syndrome. The investigations, including serological testing and endoscopic duodenal biopsy, revealed that the patient had celiac disease. After a course of gluten-free diet, his intestinal symptoms significantly improved. This case report emphasizes the importance of thorough investigations for patients with irritable bowel syndrome to exclude celiac disease.

scholarly journals Irritable Bowel Syndrome and Gluten-Related Disorders

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1117 ◽  
Author(s):  
Paolo Usai-Satta ◽  
Gabrio Bassotti ◽  
Massimo Bellini ◽  
Francesco Oppia ◽  
Mariantonia Lai ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
The Other ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Gut Permeability ◽  
Online Search ◽  
Systematic Screening ◽  
Wheat Sensitivity ◽  
Irritable Bowel

Background: Irritable bowel syndrome (IBS) is frequently associated with celiac disease (CD) and nonceliac gluten/wheat sensitivity (NCGS/NCWS), but epidemiological and pathophysiological aspects are still unclear. Furthermore, a gluten-free diet (GFD) can positively influence IBS symptoms. Methods: A comprehensive online search for IBS related to CD, NCGS and GFD was made using the Pubmed, Medline and Cochrane databases. Results: Although a systematic screening for CD in IBS is not recommended, CD prevalence can be increased in diarrhea-predominant IBS patients. On the other hand, IBS symptoms can be persistent in treated CD patients, and their prevalence tends to decrease on a GFD. IBS symptoms may overlap and be similar to those associated to nonceliac gluten and/or wheat sensitivity. Increased gut permeability could explain the gluten/wheat effects in IBS patients. Finally, a GFD could improve symptoms in a subgroup of IBS patients. Conclusions: The possible interplay between IBS and gluten-related disorders represents a scientifically and clinically challenging issue. Further studies are needed to confirm these data and better clarify the involved pathophysiological mechanisms.

Iron deficiency anemia despite effective gluten-free diet in celiac disease: Diagnostic role of small bowel capsule endoscopy

2017 ◽  
Vol 49 (4) ◽  
pp. 412-416 ◽  
Author(s):  
Konstantinos Efthymakis ◽  
Angelo Milano ◽  
Francesco Laterza ◽  
Mariaelena Serio ◽  
Matteo Neri
Keyword(s):  
Celiac Disease ◽  
Small Bowel ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Capsule Endoscopy ◽  
Gluten Free Diet ◽  
Deficiency Anemia ◽  
Gluten Free ◽  
Diagnostic Role

scholarly journals Su1452 Iron Deficiency Anemia Despite Effective Gluten-Free Diet in Celiac Disease: Diagnostic Role of Video-Capsule Endoscopy

2014 ◽  
Vol 146 (5) ◽  
pp. S-472
Author(s):  
Konstantinos Efthymakis ◽  
Angelo Milano ◽  
Francesco Laterza ◽  
Mariaelena Serio ◽  
Matteo Neri
Keyword(s):  
Celiac Disease ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Capsule Endoscopy ◽  
Gluten Free Diet ◽  
Video Capsule Endoscopy ◽  
Deficiency Anemia ◽  
Gluten Free ◽  
Diagnostic Role

scholarly journals Gluten-Associated Pathology: Focusing on Patients with Irritable Bowel Syndrome

2020 ◽  
Vol 16 (30) ◽  
pp. 66-73
Author(s):  
O.V. Gaus ◽  
◽  
M.A. Livzan ◽  
D.V. Popello
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Clinical Symptoms ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Wheat Allergy ◽  
The World ◽  
Wheat Products ◽  
Irritable Bowel ◽  
The Many

Wheat is an essential part of the diet of many people around the world. Despite the many beneficial aspects of eating wheat products, they can be associated with the development of a variety of diseases. The spectrum of gluten-associated pathologies includes celiac disease, wheat allergy, and non-celiac gluten sensitivity (NCGS). The clinical symptoms of gluten-associated pathology are similar to those of irritable bowel syndrome (IBS). Diagnosis of celiac disease and wheat allergy is now straightforward. NCGS remains a diagnosis of exclusion due to the lack of specific biomarkers and standardized research methods. Many patients with IBS consider themselves gluten-sensitive and their symptoms are relieved by a gluten-free diet. Most likely it is NCGS that occurs in a heterogeneous group of patients with IBS. However it remains controversial whether the development of symptoms in this case is associated with gluten itself or with other components of wheat, such as non-gluten proteins and FODMAPs.

scholarly journals Persistent Iron Deficiency Anemia in Patients with Celiac Disease Despite a Gluten-Free Diet

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2176
Author(s):  
Gianpiero Stefanelli ◽  
Angelo Viscido ◽  
Salvatore Longo ◽  
Marco Magistroni ◽  
Giovanni Latella
Keyword(s):  
Celiac Disease ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Villous Atrophy ◽  
Gluten Free Diet ◽  
Deficiency Anemia ◽  
Gluten Free ◽  
Anemia Of Chronic Disease ◽  
Therapeutic Implications ◽  
Molecular Alterations

Celiac disease (CD) is an autoimmune disorder characterized by intolerance to dietary gluten in genetically predisposed subjects. Iron deficiency anemia (IDA) is a common sign in CD, being the only abnormality in approximately 40% of celiac patients. A multifactorial etiology leads to IDA in CD. The two main causes are the villous atrophy of the mucosa at the site of iron absorption (the duodenum) and the resulting inflammation, which triggers the mechanism that leads to the anemia of chronic disease. Until now, it has been unclear why some patients with CD continue to have IDA despite a careful gluten-free diet (GFD) and the normalization of villous atrophy. Furthermore, some celiac patients are refractory to oral iron supplementation despite the healing of the mucosa, and they thus require periodic intravenous iron administration. The Marsh classification evaluates the degree of inflammation and villous atrophy, but it does not assess the possible persistence of ultrastructural and molecular alterations in enterocytes. The latter was found in CD in remission after adopting a GFD and could be responsible for the persistently reduced absorption of iron and IDA. Even in non-celiac gluten sensitivity, anemia is present in 18.5–22% of patients and appears to be related to ultrastructural and molecular alterations in intestinal microvilli. It is possible that a genetic component may also play a role in IDA. In this review, we evaluate and discuss the main mechanisms of IDA in CD and the possible causes of its persistence after adopting a GFD, as well as their therapeutic implications.

Very Severe Iron-Deficiency Anemia in a Patient with Celiac Disease and Bulimia Nervosa: A Case Report

2005 ◽  
Vol 82 (4) ◽  
pp. 310-311 ◽  
Author(s):  
Philipp J. Jost ◽  
Svenja M. Stengel ◽  
Wolfgang Huber ◽  
Mario Sarbia ◽  
Christian Peschel ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Iron Deficiency ◽  
Bulimia Nervosa ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia
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