scholarly journals Clinically detection of foot and mouth disease at Kapasia upazila under Gazipur dristrict in Bangladesh

2017 ◽  
Vol 14 (2) ◽  
pp. 185-190 ◽  
Author(s):  
MA Alam ◽  
MR Amin ◽  
TK Paul ◽  
MK Rizon
Keyword(s):  
Control Strategies ◽  
Winter Season ◽  
Foot And Mouth Disease ◽  
Farming System ◽  
Mouth Disease ◽  
Mouth Diseases ◽  
Intensive Farming ◽  
Foot And Mouth ◽  
Potential Risk Factors ◽  
And Control

Clinical detection of Foot and Mouth Disease in the cattle which study was carried out in Kapasia upazila under Gazipur district during from February 2011 to January 2012 and identifying the potential risk factors associated with the studies in Kapasia, Gazipur. A total of 315 infected cattle of different age, sex were examined in the upazila veterinary development center of Kapasia in Gazipur district. Total 86 (27.30%) cattle were infected with FMD on the basis of clinico-epidemiological determinants. The effect of season, Breed, Age, and sex of cattle on the incidence of the disease was discussed. It was observed that rural farming system (30.43%) was more susceptible than intensive farming (21.30%) system of cattle. Old animals (33.15%) were more susceptible than adult (21.81%) and young (15.71%). The prevalence of disease was found significantly (P < 0.05) higher in male (33.65%) than in female (24.17%). It was observed that local breed cattle (35.48%) were more susceptible than cross-breed cattle (15.50%). Seasonal variation of the disease was significant in the study area. The infection was less in summer (11.63%) and increasing in rainy season (25.58%) but gradually increased in late period of winter season (62.80%). This report will help to prioritize and control strategies against Foot and Mouth diseases from Kapasia upazila at Gazipur District in Bangladesh.J. Bangladesh Agril. Univ. 14(2): 185-190, December 2016

scholarly journals Prevalence of foot and mouth disease (FMD) in cattle at Meghna upazila in Comilla in Bangladesh

1970 ◽  
Vol 7 (2) ◽  
pp. 317-319 ◽  
Author(s):  
MA Mannan ◽  
MP Siddique ◽  
MZ Uddin ◽  
MM Parvaz
Keyword(s):  
Winter Season ◽  
Foot And Mouth Disease ◽  
Farming System ◽  
Mouth Disease ◽  
Indigenous Cattle ◽  
Adult Cattle ◽  
Disease Epidemiology ◽  
Foot And Mouth ◽  
Veterinary Hospital ◽  
Effect Of Age

The present study was performed in the Upazila Veterinary Hospital, Meghna, Comilla during the period from September 2006 to February 2007 to observe the prevalence of Foot and Mouth Disease (FMD) in cattle at Meghna upazila in Comilla. A total of 253 skin diseased cattle head were examined in this study where 109 were males and 144 were females. The prevalence of FMD was 24.51% at Meghna upazila. The effect of age, sex, breed, season and farming system on the incidence rate of the disease was discussed. Seasonal variation on outbreak of this disease was significantly higher. The clinical prevalence of FMD was highest in the month of November (34.69%) and December (36.20%). The males (35.77%) were more susceptible than females (15.97%). The adult cattle (34.18%) were more susceptible compared to heifer (23.43%) and young (09.72%). In breed, 39.18% indigenous breeds and 15.38% crossed breeds were infected by FMD. So, it could be concluded that the rural farming system, adult, male and the indigenous cattle were more susceptible to FMD in winter season. Keywords: Foot and Mouth Disease; Epidemiology; Clinical features; Breed DOI: 10.3329/jbau.v7i2.4741 J. Bangladesh Agril. Univ. 7(2): 317-319, 2009

scholarly journals Use of an automatic needle-free injection device for foot-and-mouth disease vaccination in dairy heifers

2021 ◽  
Vol 66 (No. 3) ◽  
pp. 87-93
Author(s):  
S Wataradee ◽  
T Boonserm ◽  
C Srangaprakon ◽  
K Ajariyakhajorn ◽  
C Inchaisri
Keyword(s):  
Control Strategies ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Hypodermic Needle ◽  
Serological Response ◽  
Injection Device ◽  
Dairy Heifers ◽  
Foot And Mouth ◽  
Injection Methods ◽  
And Control

The foot-and-mouth disease (FMD) vaccination of Thai dairy cows is routinely conducted to control and prevent the disease. In Thailand, FMD control strategies include a subcutaneous route (s.c.) vaccination with 2 ml of inactivated FMD vaccine 2–3 times a year produced by the Department of Livestock Development (DLD). A new way of vaccination was introduced in the form of an automatic needle-free injection device. This technology has several important advantages, such as requiring less animal restraint, reduced time and labour with high precision, and a consistent delivery system. Here, the effectiveness of an automatic needle-free injection (ANFI) device was evaluated in 30 dairy heifers (randomly divided into three groups, 10 in each group) in the FMD vaccine delivery. The first group was subcutaneously (s.c.) vaccinated using a conventional hypodermic needle with 2 ml of the vaccine, the second group received the same, but using a CO<sub>2</sub>-powered ANFI device, and the third group received the vaccine using the same ANFI device, but administered intradermally (i.d.) with only 1 ml of the vaccine. The blood samples collected up to 120 days post-vaccination revealed that both injection methods resulted in a similar serological response. The results suggest that the i.d. and s.c. ANFI systems are effective and safe. Moreover, the i.d. use of the ANFI enabled the possibility to half the vaccination dose with the same efficacy. Therefore, the ANFI can be used as an alternative approach for FMD vaccination by s.c. or i.d. routes in dairy cows in Thailand. Ultimately, reducing the use of restraint devices and labour will improve the vaccination for the prevention and control of FMD and may improve the cows’ welfare.

scholarly journals Synthetic peptide vaccine for Foot-and-Mouth Disease: synthesis, characterization and immunogenicity

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Banu Mansuroğlu ◽  
Serap Derman ◽  
Kadriye Kızılbey ◽  
Sezen Canım Ateş ◽  
Zeynep Mustafaeva Akdeste
Keyword(s):  
Synthetic Peptide ◽  
General Pattern ◽  
Peptide Vaccine ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Water Soluble ◽  
Peptide Sequence ◽  
Free Peptide ◽  
Foot And Mouth ◽  
And Control

AbstractBackgroundThe conjugations of antigenic synthetic peptide sequences with carrier polymers have opened new possibilities for the treatment of diseases. In this study, 135–161 peptide sequence of VP1 capsid protein of Foot-and-Mouth Disease was cross-linked with P(VP-co-AA) copolymer by covalent conjugation using water-soluble carbodiimide at different ratio of components (γ=5, 7, 9, 11, 15) for the first time in the literature.Materials and methodsBioconjugates were characterized by gel permeation chromatography and fluorescence spectroscopy to identify occurrences of the conjugates. After characterization, γ=15 bioconjugate was determined as optimum conjugate for immunization studies and IC50 value is calculated as 1.227 mg/mL. By determining the nontoxic range, indirect ELISA were performed to evaluate the immune response elicited in balb/c mice by either peptide or P(VP-co-AA)-peptide bioconjugates (γ=15). Two injections were applied to each group and high immune responses were obtained against γ=15 conjugate compared to free peptide and control.Results and conclusionAt the end of 9-week, the general pattern of immunoreactivity was acquired as γ=15>>peptide>control. Peptide formulated in the conjugated form had higher antibody response than free peptide and control (p<0.01, for all in both cases), this conjugate formulation put forward the adjuvant activity of P(VP-co-AA) polymer.

Assessment of foot-and-mouth disease risk areas in mainland China based spatial multi-criteria decision analysis

2021 ◽  
Author(s):  
Wang Haoran ◽  
Xiao Jianhua ◽  
Ouyang Maolin ◽  
Gao Hongyan ◽  
Bie Jia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Decision Analysis ◽  
Disease Risk ◽  
Mainland China ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Multi Criteria Decision Analysis ◽  
Foot And Mouth ◽  
Risk Areas ◽  
And Control

Abstract Background Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. As a transboundary animal disease, the prevention and control of FMD are important. This study was based on spatial multi-criteria decision analysis (MCDA) to assess FMD risk areas in mainland China. Ten risk factors were identified for constructing risk maps by scoring, and the analytic hierarchy process (AHP) was used to calculate the criteria weights of all factors. Different risk factors had different units and attributes, and fuzzy membership was used to standardize the risk factors. The weighted linear combination (WLC) and one-at-a-time (OAT) were used to obtain risk and uncertainty maps as well as to perform sensitivity analysis. Results Four major risk areas were identified in mainland China, including western (Xinjiang and Tibet), southern (Yunnan, Guizhou, Guangxi and Guangdong), northern (Gansu, Ningxia and Inner Mongolia), and eastern (Hebei, Henan, Anhui, Jiangsu and Shandong). We found spring as the main season for FMD outbreaks. Risk areas were associated with the distance to previous outbreak points, grazing areas and cattle density. Receiver operating characteristic (ROC) analysis indicated that the risk map had good predictive power (AUC = 0.8532). Conclusions These results can be used to delineate FMD risk areas in mainland China, and provinces can adopt the targeted preventive measures and control strategies.

scholarly journals The Effectiveness of a Foot and Mouth Disease Outbreak Control Programme in Thailand 2008–2015: Case Studies and Lessons Learned

2018 ◽  
Vol 5 (4) ◽  
pp. 101 ◽  
Author(s):  
Terdsak Yano ◽  
Sith Premashthira ◽  
Tosapol Dejyong ◽  
Sahatchai Tangtrongsup ◽  
Mo D. Salman
Keyword(s):  
Prevention And Control ◽  
Animal Movement ◽  
Foot And Mouth Disease ◽  
Control Programme ◽  
Mouth Disease ◽  
Lessons Learned ◽  
Control Measures ◽  
Prevention Measures ◽  
Foot And Mouth ◽  
And Control

Three Foot and Mouth Disease (FMD) outbreaks in northern Thailand that occurred during the implementation of the national FMD strategic plan in 2008–2015 are described to illustrate the lessons learned and to improve the prevention and control of future outbreaks. In 2008, during a FMD outbreak on a dairy farm, milk delivery was banned for 30 days. This was a part of movement management, a key strategy for FMD control in dairy farms in the area. In 2009, more than half the animals on a pig farm were affected by FMD. Animal quarantine and restricted animal movement played a key role in preventing the spread of FMD. In 2010, FMD infection was reported in a captive elephant. The suspected source of virus was a FMD-infected cow on the same premises. The infected elephant was moved to an elephant hospital that was located in a different province before the diagnosis was confirmed. FMD education was given to elephant veterinarians to promote FMD prevention and control strategies in this unique species. These three cases illustrate how differences in outbreak circumstances and species require the implementation of a variety of different FMD control and prevention measures. Control measures and responses should be customized in different outbreak situations.

scholarly journals Innate Immune Defenses Induced by CpG Do Not Promote Vaccine-Induced Protection against Foot-and-Mouth Disease Virus in Pigs

2009 ◽  
Vol 16 (8) ◽  
pp. 1151-1157 ◽  
Author(s):  
M. P. Alves ◽  
L. Guzylack-Piriou ◽  
V. Juillard ◽  
J.-C. Audonnet ◽  
T. Doel ◽  
...  
Keyword(s):  
Disease Virus ◽  
Large Scale ◽  
Control Strategies ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Innate Immune ◽  
Noticeable Effect ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Natural Hosts

ABSTRACT Emergency vaccination as part of the control strategies against foot-and-mouth disease virus (FMDV) has the potential to limit virus spread and reduce large-scale culling. To reduce the time between vaccination and the onset of immunity, immunostimulatory CpG was tested for its capacity to promote early protection against FMDV challenge in pigs. To this end, CpG 2142, an efficient inducer of alpha interferon, was injected intramuscularly. Increased transcription of Mx1, OAS, and IRF-7 was identified as a sensitive measurement of CpG-induced innate immunity, with increased levels detectable to at least 4 days after injection of CpG formulated with Emulsigen. Despite this, CpG combined with an FMD vaccine did not promote protection. Pigs vaccinated 2 days before challenge had disease development, which was at least as acute as that of unvaccinated controls. All pigs vaccinated 7 days before challenge were protected without a noticeable effect of CpG. In summary, our results demonstrate the caution required when translating findings from mouse models to natural hosts of FMDV.

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