scholarly journals A RARE FORM OF PRESENTATION OF A SMALL INTESTINE GIST IN THE EMERGENCY DEPARTMENT

2021 ◽  
Vol 2 (2) ◽  
pp. 66-71
Author(s):  
Dan Nicolae Păduraru ◽  
Ion Daniel ◽  
Alexandra Bolocan ◽  
Florentina Mușat ◽  
Cosmin Alexandru Palcău ◽  
...  
Keyword(s):  
Small Intestine ◽  
Intestinal Tract ◽  
Kinase Inhibitor ◽  
Close Contact ◽  
Neoadjuvant Treatment ◽  
Mesenchymal Tumors ◽  
Moderate Anemia ◽  
Jejunal Tumor ◽  
Gastro Intestinal Tract ◽  
Superior Pole

Gastro-intestinal stromal tumors are a form of mesenchymal tumors most commonly located in the gastro-intestinal tract, as the name suggests. The symptoms that might occur can be abdominal pain or discomfort, early satiety, bloating, jaundice, fatigue, hematemesis or melena. Most of GISTs (>95%) are positive for the KIT protein. Surgery remains the only curative treatment for GIST amenable for resection. High risk tumors can receive adjuvant or neoadjuvant treatment with Imatinib Mesylate, a tyrosin-kinase inhibitor. We present the case of a 59-years old patient that presented with rectal bleeding and abdominal diffuse pain. Blood tests shows leukocytosis and moderate anemia. CT scan describes an expansive, polycyclic process projected at the limit between the mesogastric region and the left flank, in close contact with the small intestine without any clear demarcation line between them and at the superior pole of the tumor, located in an enteral loop, a band of hyperdensity with net contour. Intraoperative, an extraluminal jejunal tumor was found, located at 15 cm from the duodeno-jejunal flexure, with intraluminal active bleeding, which lead us to suspect a GIST based on the macroscopic aspect. We performed segmental enterectomy of 10 cm of the small intestine containing the tumor with entero-enteral anastomosis end to end. The histopathological and immunohistochemistry examinations correlated with the macroscopic aspect have confirmed the diagnosis of GIST.

scholarly journals Observations on the fermentation of carbohydrates along the gastro-intestinal tract of a fistulated cow.

1973 ◽  
Vol 21 (3) ◽  
pp. 217-226
Author(s):  
B.D.E. Gaillard ◽  
A.T. van 't Klooster
Keyword(s):  
Small Intestine ◽  
Intestinal Tract ◽  
Soluble Fraction ◽  
Soluble Sugars ◽  
Water Soluble ◽  
Uronic Acids ◽  
Glucose Polymer ◽  
Intestinal Contents ◽  
Cellulose Fermentation ◽  
Gastro Intestinal Tract

One cow was provided with cannulae in the proximal duodenum and terminal ileum. Three experimental rations were offered: 1, hay 7 kg/day and concentrate 6; 2, hay 3 kg/day, paper pulp 3 and concentrate 3.7; 3, fresh grass 11 kg DM/day. Rations 2 and 2 were given twice daily and 3 was offered more frequently. Experimental periods were 5 days in experiment 1 and 7 days in 2 and 3. Samples were taken from each cannula every 2 h for 5 days. Faeces were collected in each period. Flow rate of the intestinal contents was measured with polyethylene glycol and chromium sesquioxide as markers. Carbohydrates in the feed, digesta and faeces were fractionated according to solubility into ethanol-soluble sugars, alpha -glucose polymers, fructosan, water-soluble polysaccharides other than alpha -glucose polymers and fructosan, neutral-detergent-soluble polysaccharides and neutral-detergent residue. Sugars, sialic and uronic acids were measured in the hydrolysates and the sugars were separated chromatographically.Most of the ethanol-soluble sugars and all the fructosan was digested in the rumen, reticulum, omasum and abomasum, considered collectively as the stomach. Digestion of alpha -glucose polymer occurred mainly in the stomach and only 5 to 10% was digested in the small intestine and caecum with colon. The hay and concentrate ration contained more starch than the others and a higher proportion of this was digested in the small intestine and caecum with colon (20.3 and 6.8% of the digestible starch). The water-soluble fraction was digested mostly in the stomach; on rations 1 and 3 more component carbohydrates disappeared from the small intestine than the caecum with colon. Bacterial polysaccharides were thought to be digested in the small intestine and some bacterial growth was indicated, particularly on ration 2 which contained large amounts of cellulose. Fermentation and addition of bacterial polysaccharides and mucus confused the picture of digestion of the neutral-detergent-soluble fraction, but on all 3 rations it was higher in the small intestine than in the caecum with colon. The neutral-detergent residue was mainly fermented in the stomach and the caecum with colon. (Abstract retrieved from CAB Abstracts by CABI’s permission)

INTRAVENOUS SOMATOSTATIN INFUSION AFFECTS GASTRO-INTESTINAL TRACT FUNCTION IN SHEEP

1984 ◽  
Vol 64 (5) ◽  
pp. 93-94 ◽  
Author(s):  
G. J. FAICHNEY ◽  
T. N. BARRY
Keyword(s):  
Small Intestine ◽  
Key Words ◽  
Large Intestine ◽  
Retention Time ◽  
Intestinal Tract ◽  
Proximal Colon ◽  
Mean Retention Time ◽  
Gut Function ◽  
Tract Function ◽  
Gastro Intestinal Tract

Intravenous somatostatin infusion to anestrous ewes decreased the weight of all postomasal gut tissues, produced small increases in total 51Cr-EDTA and, 103Ru-phen mean retention times, increased the proportion of the total mean retention time spent in the abomasum + small intestine + cecum/proximal colon and decreased the proportion spent in the distal large intestine. Key words: Somatostatin, gut function, marker retention times

Species of Gastro-intestinal Helminths of Lambs in Northern Ireland

1972 ◽  
Vol 46 (3) ◽  
pp. 285-290 ◽  
Author(s):  
S. M. Taylor ◽  
R. J. G. Cawthorne
Keyword(s):  
Small Intestine ◽  
Northern Ireland ◽  
Intestinal Tract ◽  
Intestinal Helminths ◽  
Relative Incidence ◽  
Major Species ◽  
Gastro Intestinal Tract ◽  
Prevalent Species

A survey of the helminths parasitising the gastro-intestinal tract of lambs in Northern Ireland is described. Twenty-four species were identified from the three hundred and seventy-two animals examined, which were drawn from abattoirs in different areas.The major species found in the abomasum were Ostertagia circumcincta, 0. trifurcata, 0. pinnata and Trichosirongylus axei. Nematodints battus, N. filicollis, T. vitrinus and Cooperia curticei were the most prevalent species in the small intestine. Some observations are made on the relative incidence and role in the production of parasitic gastro-enteritis.

scholarly journals A gastrointestinal stromal tumor: Case report

2006 ◽  
Vol 59 (9-10) ◽  
pp. 487-489
Author(s):  
Milivoje Vukovic ◽  
Nebojsa Moljevic ◽  
Dragan Krivokuca
Keyword(s):  
Small Intestine ◽  
Case Report ◽  
Surgical Resection ◽  
Kinase Inhibitor ◽  
Iliac Fossa ◽  
Primary Treatment ◽  
Clinical Findings ◽  
Mesenchymal Tumors ◽  
The Right ◽  
Surgery Department

Introduction. Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. They frequently occur in the stomach and small intestine, but they rarely occur in the colon and rectum. Case report. This is a case report of a patient with a GIST involving the cecum, and acute obstruction of the small intestine. A 47-year- old male patient was admitted to the emergency surgery department with abdominal pain and distension lasting for a few days. Clinical examination revealed tenderness in the right iliac fossa. Routine hematologic testing revealed anemia, and abdominal x-ray multiple air-fluid levels in the small intestine. Based on the clinical findings, we decided to perform an explorative laparotomy. A large cecal tumor was detected. The proximal parts of the small intestine were severely distended. Discussion and Conclusion. GISTs are more common in the stomach (60-70%) and the small intestine (25-35%), than in the colon, rectum and esophagus. The most frequent complications associated with GISTs are obstructions and hemorrhages. Surgical resection is the primary treatment of GISTs. Radiotherapy and chemotherapy are generally ineffective. Continuous postoperative follow-up is necessary, because most recurrences occur within the first 2 years after complete surgical resection. In the past few years, surgical resection was followed by adjuvant tyrosine kinase inhibitor therapy. .

THE INFLUENCE OF PROTEIN LEVEL ON THE NITROGEN ABSORPTION IN THE GASTRO-INTESTINAL TRACT OF DAIRY COWS FED GRASS SILAGE FERTILIZED WITH TWO LEVELS OF NITROGEN

1984 ◽  
Vol 64 (5) ◽  
pp. 191-192 ◽  
Author(s):  
P. D. MØLLER ◽  
V. FRIIS KRISTENSEN ◽  
P. E. ANDERSEN
Keyword(s):  
Small Intestine ◽  
Dairy Cows ◽  
Protein Level ◽  
Intestinal Tract ◽  
Nitrogen Absorption ◽  
Grass Silage ◽  
Significant Difference ◽  
Gastro Intestinal Tract ◽  
Low Nitrogen ◽  
Key Words Nitrogen

Increased recycling of nitrogen to the forestomachs on low nitrogen rations was found. On high CP rations the AAN at duodenum was greater than or equal to the N intake. Apparently absorbed TN in the small intestine was increased on the SBM supplemented ration. No significant difference was found for absorbed AAN fractions. Key words: Nitrogen, cattle, metabolism, gastro-intestinal tract

Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine

2010 ◽  
Vol 1 (1) ◽  
pp. 31-36 ◽  
Author(s):  
A. Maathuis ◽  
D. Keller ◽  
S. Farmer
Keyword(s):  
Small Intestine ◽  
Milk Protein ◽  
Intestinal Tract ◽  
In Vitro Model ◽  
Bacillus Coagulans ◽  
Protein Digestion ◽  
Vitro Model ◽  
Gastro Intestinal Tract ◽  
Carbohydrate Digestion

We have investigated the survival and activity of GanedenBC30 during passage through the upper gastro-intestinal tract. GanedenBC30 was tested in a dynamic, validated, in vitro model of the stomach and small intestine (TIM-1) on survival and its potential to aid in digestion of milk protein, lactose and fructose. The survival of GanedenBC30 was high (70%), although germination of the spores was minimal (<10%) under the conditions tested. Survival of the strain in the presence of lactose and fructose was markedly lower (56-59%) than in the absence of the sugars. The amount of digested milk protein available for absorption was somewhat higher (+0.2 g) when GanedenBC30 was added to the milk. When GanedenBC30 was tested with lactose or fructose added to the meal, the cumulative amount of lactate produced was slightly higher (+0.12-0.18 mmol) compared to the GanedenBC30 alone. In conclusion, although the differences in survival of GanedenBC30 are small, these results show the potential of GanedenBC30 to aid in protein digestion and in the digestion of lactose and fructose. If a larger fraction of the Bacillus coagulans cells had germinated, the influence on protein and carbohydrate digestion would probably have been much greater. Importance of the findings: the potential of GanedenBC30 to aid in the digestion of lactose and fructose could be used to prevent occurrence of intestinal symptoms in individuals sensitive to these carbohydrates.

1.2 Post-Ruminal Digestion and the Utilization of Nitrogen

1982 ◽  
Vol 6 ◽  
pp. 13-22 ◽  
Author(s):  
D. B. Lindsay ◽  
D. G. Armstrong
Keyword(s):  
Amino Acids ◽  
Small Intestine ◽  
Nucleic Acids ◽  
Intestinal Tract ◽  
Preceding Paper ◽  
Current Understanding ◽  
Ruminant Animal ◽  
Gastro Intestinal Tract ◽  
Ruminal Digestion ◽  
Microbial Mass

The preceding paper has detailed our current understanding of the processes of N digestion in the ruminant animal as they relate to the events occurring within the reticulo-rumen. It is the purpose of this paper to consider the processes of digestion occurring principally within the small intestine and to comment on the significance of events occurring within the caecum and colon in so far as they relate to nitrogen digestion. The fate of amino acids subsequent to their absorption from the gastro-intestinal tract will also be discussed, in particular the way they are catabolized and whether this limits their availability for the synthesis of protein. Reference will also be made to purine and pyrimidine nitrogen; these products arise from the considerable content of nucleic acids in the microbial mass which leaves the reticulo-rumen and undergoes digestion in the small intestine.

Adaptation ofCryptosporidiumoocysts to different excystation conditions

Parasitology ◽  
2007 ◽  
Vol 134 (11) ◽  
pp. 1583-1588 ◽  
Author(s):  
G. WIDMER ◽  
P. KLEIN ◽  
R. BONILLA
Keyword(s):  
Small Intestine ◽  
Intestinal Tract ◽  
Taurocholic Acid ◽  
The Other ◽  
Effect Of Temperature ◽  
Neutral Solution ◽  
Acid Environment ◽  
Gastro Intestinal Tract

SUMMARYWithin the genusCryptosporidium2 lineages have evolved, one adapted to the acid environment of the stomach and abomasum, the other comprising parasites that multiply in the small intestine. We tested whether the release of sporozoites from oocysts, a process known as excystation, is triggered by conditions which mimic the site of infection. Specifically, we exposed oocysts from gastric and intestinalCryptosporidiumspecies to acid conditions or to a neutral solution of taurocholic acid, at 37°C. We found that oocysts from the gastric speciesC. murisandC.andersoniexcysted in both conditions, whereas the intestinal speciesC. parvumandC. hominisdid not respond to acid. When the effect of temperature alone was tested onC. murisandC. parvum, only oocysts from the former species excysted in significant numbers. Oocysts from intestinal species did not respond to temperature alone, nor to acidity. These observations are consistent with the need of gastric species to rapidly excyst and release the sporozoites upon ingestion, and indicate thatCryptosporidiumoocysts have evolved to maximize delivery of sporozoites to the region of the gastro-intestinal tract where the parasite multiplies.

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