scholarly journals Anaerobic Solid-State Fermentation of Soybean Meal With Bacillus sp. to Improve Nutritional Quality

2021 ◽  
Vol 8 ◽  
Author(s):  
Yanhui Yao ◽  
Hongya Li ◽  
Jia Li ◽  
Baocheng Zhu ◽  
Tongguo Gao
Keyword(s):  
Solid State ◽  
Solid State Fermentation ◽  
Soybean Meal ◽  
Nutritional Quality ◽  
Large Scale ◽  
High Yield ◽  
Scale Production ◽  
Large Scale Production ◽  
The Impact

The study evaluated the impact of fermentation with Bacillus sp. on the nutritional quality of soybean meal (SBM) and the changes of bacterial community structure during fermentation. High protease-producing strains were screened to degrade SBM macromolecular protein and anti-nutritional factors (ANFs). Unsterilized SBM then underwent an anaerobic solid-state fermentation method to evaluate the effects of fermentation. Results showed that for the nine high-producing protease strains that were screened, acid-soluble protein (ASP) contents in fermented SBM increased, with the highest value found to be 13.48%, which was fermented using strain N-11. N-11 was identified as Bacillus subtilis. N-11 fermentation reduced ANFs such as glycinin and β-conglycinin by 82.38 and 88.32%, respectively. During N-11 fermentation, the bacterial richness and diversity in SBM increased but not significantly. The high-yield protease strain B. subtilis N-11 selected in this experiment improved the nutritional quality of SBM through fermentation, and it can be used for industrial large-scale production.

scholarly journals Monitoring the Quality of Laser Cutting

2018 ◽  
Vol 1 (1) ◽  
pp. 137-143
Author(s):  
Rastislav Bernát ◽  
Zoltán Záležák ◽  
Jozef Žarnovský ◽  
Norbert Kecskés ◽  
Milan Peniaško ◽  
...  
Keyword(s):  
Large Scale ◽  
Cutting Speed ◽  
Base Material ◽  
Dimensional Accuracy ◽  
Cutting Edge ◽  
Engineering Industry ◽  
Scale Production ◽  
Large Scale Production ◽  
The Impact

Abstract In engineering industry the production of components begins with separation of the base material and this technological operation can be time consuming, especially in large-scale production. Such production can be made more efficient by means of laser technology focusing on material cutting. Efficiency of cutting is determined not only by shortening of working time or energy saving, but also by the required cutting quality. In the paper we compare the impact of cutting speed changing and laser beam performance on the cutting edge quality. Based on requirements of dimensional accuracy and preset roughness of the cutting edge, we evaluated the cutting quality of laser in samples of different materials. Measured values of sample dimensions and roughness are compared in conclusions of the paper, where we estimate whether the samples meet specified requirements of dimensional accuracy and roughness of the cutting edge in order to make the production process more efficient.

Thermal Laser Separation – A Novel Dicing Technology Fulfilling the Demands of Volume Manufacturing of 4H-SiC Devices

2015 ◽  
Vol 821-823 ◽  
pp. 528-532 ◽  
Author(s):  
Dirk Lewke ◽  
Karl Otto Dohnke ◽  
Hans Ulrich Zühlke ◽  
Mercedes Cerezuela Barret ◽  
Martin Schellenberger ◽  
...  
Keyword(s):  
Experimental Data ◽  
Process Control ◽  
Tool Wear ◽  
Large Scale ◽  
State Of The Art ◽  
Scale Production ◽  
High Quality ◽  
Large Scale Production ◽  
Laser Separation

One challenge for volume manufacturing of 4H-SiC devices is the state-of-the-art wafer dicing technology – the mechanical blade dicing which suffers from high tool wear and low feed rates. In this paper we discuss Thermal Laser Separation (TLS) as a novel dicing technology for large scale production of SiC devices. We compare the latest TLS experimental data resulting from fully processed 4H-SiC wafers with results obtained by mechanical dicing technology. Especially typical product relevant features like process control monitoring (PCM) structures and backside metallization, quality of diced SiC-devices as well as productivity are considered. It could be shown that with feed rates up to two orders of magnitude higher than state-of-the-art, no tool wear and high quality of diced chips, TLS has a very promising potential to fulfill the demands of volume manufacturing of 4H-SiC devices.

scholarly journals Influência da vernalização de semente na produção, crescimento e desenvolvimento de plantas de lisianthus

2018 ◽  
Vol 39 (6) ◽  
pp. 2325 ◽  
Author(s):  
Maria Yumbla-Orbes ◽  
José Geraldo Barbosa ◽  
Wagner Campos Otoni ◽  
Marcel Santos Montezano ◽  
José Antônio Saraiva Grossi ◽  
...  
Keyword(s):  
Large Scale ◽  
Limiting Factor ◽  
Scale Production ◽  
Cut Flower ◽  
Cut Flowers ◽  
Flower Production ◽  
Commercial Scale ◽  
Large Scale Production ◽  
And Control

Flowering induction and control is a limiting factor when commercially producing cut flowers of lisianthus and seed exposure to low temperatures, a physiological event called vernalization, induces the differentiation of vegetative buds to reproductive buds, contributing to a flowering that is uniform and has quality. The objective of this study was to evaluate the influence of seed vernalization in three cultivars of lisianthus (Excalibur, Echo and Mariachi) for 12, 24, 36 and 48 days at temperatures of 5, 10 and 15°C, in the production and quality of buds, making this technology feasible to large-scale production. During cultivation it was observed that the lower the temperature and higher the vernalization period, the lower the cycle and the greater the number of plants induced to flowering for all three cultivars, and those are important features in the context of flower production in a commercial scale. The seeds subjected to vernalization originated plants that produce flower stems within the standards required by the market, showing that vernalization was efficient to induce flowering without affecting the quality of the buds. To produce lisianthus as a cut flower of quality, it is recommended seed vernalization of Mariachi and Echo cultivars for 24 days at 5°C and Excalibur for 36 days at 5°C.

scholarly journals Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening

2020 ◽  
Vol 21 (13) ◽  
pp. 4808 ◽  
Author(s):  
Simon Gutbier ◽  
Florian Wanke ◽  
Nadine Dahm ◽  
Anna Rümmelin ◽  
Silke Zimmermann ◽  
...  
Keyword(s):  
Drug Screening ◽  
Large Scale ◽  
Neoplastic Cell ◽  
Leukemic Cells ◽  
High Yield ◽  
Scale Production ◽  
Large Scale Production ◽  
Compound Screening ◽  
Health And Disease ◽  
Induced Pluripotent

Tissue-resident macrophages are key players in inflammatory processes, and their activation and functionality are crucial in health and disease. Numerous diseases are associated with alterations in homeostasis or dysregulation of the innate immune system, including allergic reactions, autoimmune diseases, and cancer. Macrophages are a prime target for drug discovery due to their major regulatory role in health and disease. Currently, the main sources of macrophages used for therapeutic compound screening are primary cells isolated from blood or tissue or immortalized or neoplastic cell lines (e.g., THP-1). Here, we describe an improved method to employ induced pluripotent stem cells (iPSCs) for the high-yield, large-scale production of cells resembling tissue-resident macrophages. For this, iPSC-derived macrophage-like cells are thoroughly characterized to confirm their cell identity and thus their suitability for drug screening purposes. These iPSC-derived macrophages show strong cellular identity with primary macrophages and recapitulate key functional characteristics, including cytokine release, phagocytosis, and chemotaxis. Furthermore, we demonstrate that genetic modifications can be readily introduced at the macrophage-like progenitor stage in order to interrogate drug target-relevant pathways. In summary, this novel method overcomes previous shortcomings with primary and leukemic cells and facilitates large-scale production of genetically modified iPSC-derived macrophages for drug screening applications.

scholarly journals Upgrading the Nutritional Value of Rice Bran by Solid-State Fermentation with Pleurotus sapidus

Fermentation ◽  
2019 ◽  
Vol 5 (2) ◽  
pp. 44 ◽  
Author(s):  
Omarini ◽  
Labuckas ◽  
Zunino ◽  
Pizzolitto ◽  
Fernández-Lahore ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Solid State ◽  
Rice Bran ◽  
Solid State Fermentation ◽  
Acid Content ◽  
Nutritional Quality ◽  
Oleic Acid Content ◽  
Pleurotus Sapidus ◽  
Process Strategy

Solid-state fermentation (SSF) of rice bran (RB) employing the edible fungus Pleurotus sapidus was investigated as a process strategy to improve the nutritional quality of this low-cost and abundant substrate. During fermentation, samples were withdrawn at different time intervals (4, 6, and 10 days) and further analyzed. Established methods were deployed to monitor the changes in nutritional composition (carbohydrates, proteins, ash, and lipids). Additionally, changes in fatty acid composition was studied as a function of culture progress. Results showed that the SSF of rice bran increased total carbohydrates from 36.6% to 50.2%, total proteins from 7.4% to 12.8%, and ash from 7.6% to 11.5%. However, the total lipid content was reduced from 48.5% to 27.8%. The fatty acid (FA) composition of RB included mainly oleic, linoleic, and palmitic acids. Upon fermentation with P. sapidus, small differences were found: linoleic acid and oleic acid content were increased by 0.4% and 1.1%, respectively, while palmitic acid content was reduced by 0.8%. This study demonstrated an improvement in the nutritional quality of RB after fermentation with P. sapidus, since protein, carbohydrates, minerals, and specific FA components were increased. As a whole, our results indicate that fermented rice bran could be used as a high-quality animal feed supplement.

scholarly journals Smoking control: challenges and achievements

2016 ◽  
Vol 42 (4) ◽  
pp. 290-298 ◽  
Author(s):  
Luiz Carlos Corrêa da Silva ◽  
Alberto José de Araújo ◽  
Ângela Maria Dias de Queiroz ◽  
Maria da Penha Uchoa Sales ◽  
Maria Vera Cruz de Oliveira Castellano
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Large Scale ◽  
Scale Production ◽  
Large Scale Production ◽  
Care Policies ◽  
Promising Area ◽  
Health Care Policies ◽  
Smoking Control

ABSTRACT Smoking is the most preventable and controllable health risk. Therefore, all health care professionals should give their utmost attention to and be more focused on the problem of smoking. Tobacco is a highly profitable product, because of its large-scale production and great number of consumers. Smoking control policies and treatment resources for smoking cessation have advanced in recent years, showing highly satisfactory results, particularly in Brazil. However, there is yet a long way to go before smoking can be considered a controlled disease from a public health standpoint. We can already perceive that the behavior of our society regarding smoking is changing, albeit slowly. Therefore, pulmonologists have a very promising area in which to work with their patients and the general population. We must act with greater impetus in support of health care policies and social living standards that directly contribute to improving health and quality of life. In this respect, pulmonologists can play a greater role as they get more involved in treating smokers, strengthening anti-smoking laws, and demanding health care policies related to lung diseases.

Composición química y calidad nutritiva de garbanzo (Cicer arietinum L.) fresco y endurecido después de la fermentación en estado sólido (FES)/Chemical composition and nutritional quality of fresh and hardened chickpea (Cicer arietinum L) after the solid state fermentation (SSF)

2000 ◽  
Vol 6 (3) ◽  
pp. 251-258 ◽  
Author(s):  
C. Reyes-Moreno ◽  
C.A. Romero-Urias ◽  
J. Milan-Carrillo ◽  
R.M. Gomez-Garza
Keyword(s):  
Chemical Composition ◽  
Solid State ◽  
Phytic Acid ◽  
Cicer Arietinum ◽  
Solid State Fermentation ◽  
Nutritional Quality ◽  
Dry Matter ◽  
Cicer Arietinum L ◽  
Ssf Process

Solid state fermentation (SSF) represents a technological alternative for a great variety of legumes and cereals, or combinations of them, to improve their nutritional quality and to obtain edible products with palatable sensorial characteristics. Chickpeas (Cicer arietinum L.) are prone to develop the hardening phenomenon, also known as hard-to-cook (HTC) defect, when stored under adverse conditions of high temperature (≥ 25 °C) and high relative humidity (≥ 65%). This hard-to-cook phenomenon causes increases in cooking time, decreases in nutritional quality and deterioration of sensorial attributes of chickpea. The objective of this work was to study the effect of SSF on chemical composition and nutritional quality of fresh and hardened chickpeas. The hardening of chickpea ( Cicer arietinum L. Blanco Sinaloa 92 variety) for human consumption, was produced by accelerated storage (33-35 °C, RH = 75%, 180 days). A Rhizopus stolonifer spore suspension (1 x 106 spores/mL) was used as starter for the fermentation. The temperature and time of the SSF process were 35.8 °C and 42.7 h, respectively. The tempeh was obtained from fresh and hardened chickpea. The SSF process caused a significant increase ( p ≤ 0.05) in crude protein, true protein (19.6-19.9 to 23.2-23.4%), protein solubility, in vitro digestibility (68.6-73.1% to 79.9-80.5%), available lysine (2.19-3.04 to 3.19-4.07 g lysine/ 16 N), palmitic acid, and stearic acid, and a significant decrease ( p ≤ 0.05) in lipids, minerals, linoleic acid, phytic acid (8.82-10.73 to 2.11 g phytic acid/g dry matter), and tannins (16.1-22.4 to 3 mg catechin/g dry matter). The SSF process improved significantly the quality of fresh and hardened chickpea.

Polycultural System of Freshwater Fish in China

1982 ◽  
Vol 39 (1) ◽  
pp. 143-150 ◽  
Author(s):  
Lin Hao-Ren
Keyword(s):  
Large Scale ◽  
Feeding Habits ◽  
Fish Culture ◽  
Scale Production ◽  
Conventional Agriculture ◽  
Quality Of Water ◽  
Large Scale Production ◽  
Major Development ◽  
Lh Rh

China is a country in which fish culture is closely integrated with conventional agriculture. Its success depends on the firm base of traditional practices as well as the introduction of many innovations. Among them, polyculture is probably the most important reason for fish culture's success. The major advantage of polyculture is to utilize fully the space and food available in the pond and to optimize interactions between compatible species with different feeding habits and ecology. The different types of polycultural pond stocking are adapted in accordance with (1) the climate, (2) quality of water supply and fertility of pond, (3) availability of fish fry and fingerlings, (4) availability of food and fertilizer, and (5) market requirements. The artificial propagation of cultured fishes and large-scale production of fry and fingerlings are the major development of Chinese fish culture in recent years. The application of LH–RH analogue as a new highly effective ovulating agent for fish reproduction has been carried furthest in China.Key words: China, fish polyculture, Chinese carp, induced spawning, LH–RH analogue, fry, fingerling, fish production

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