scholarly journals Impact of Aperture, Depth, and Acoustic Clutter on the Performance of Coherent Multi-Transducer Ultrasound Imaging

2020 ◽  
Vol 10 (21) ◽  
pp. 7655
Author(s):  
Laura Peralta ◽  
Alessandro Ramalli ◽  
Michael Reinwald ◽  
Robert J. Eckersley ◽  
Joseph V. Hajnal

Transducers with a larger aperture size are desirable in ultrasound imaging to improve resolution and image quality. A coherent multi-transducer ultrasound imaging system (CoMTUS) enables an extended effective aperture through the coherent combination of multiple transducers. In this study, the discontinuous extended aperture created by CoMTUS and its performance for deep imaging and through layered media are investigated by both simulations and experiments. Typical image quality metrics—resolution, contrast and contrast-to-noise ratio—are evaluated and compared with a standard single probe imaging system. Results suggest that the image performance of CoMTUS depends on the relative spatial location of the arrays. The resulting effective aperture significantly improves resolution, while the separation between the arrays may degrade contrast. For a limited gap in the effective aperture (less than a few centimetres), CoMTUS provides benefits to image quality compared to the standard single probe imaging system. Overall, CoMTUS shows higher sensitivity and reduced loss of resolution with imaging depth. In general, CoMTUS imaging performance was unaffected when imaging through a layered medium with different speed of sound values and resolution improved up to 80% at large imaging depths.

2014 ◽  
Vol 602-605 ◽  
pp. 3485-3488
Author(s):  
Yu Fa Zhang ◽  
Xiao Quan Sun

Optical detectors consist of optical lenses and sensors, which lead to great influence on image quality. The modulation transfer function (MTF) was selected as the image performance index. The influence of focal shift on MTF in optical system was studied and image quality was simulated in this article. The results show that when the focal shift quantity increases, the MTF of detector decreases accordingly, and the high-frequency messages lost gradually. The conclusion is useful for design evaluate optical imaging system.


Electronics ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 242 ◽  
Author(s):  
Pilsu Kim ◽  
Jeeun Kang ◽  
and Tai-Kyong Song

The implementation of dynamic delay calculations (DDCs) is challenging for ultra-compact ultrasound imaging due to the enormous computation and power consumption requirements. Here, we present an efficient pseudo-DDC method based on optimal zone segmentation (PDC-Optimal), which significantly decreases these requirements relative to an unconstrained DDC method: reductions in flip-flops of 84.35% and in look-up tables of 94.19%, respectively. The reductions lead to an up to 94.53% lower dynamic power consumption and provide image quality comparable to the unconstrained DDC method. The proposed PDC-Optimal method also provides adaptive flexibility between beamforming accuracy and battery life using the delay error allowance, a user-definable parameter. A conventional pseudo-DDC method using uniform zone segmentation (PDC-Conv) presented substantial image degradation in the near imaging field when the same number of zone segments was used. Therefore, the PDC-Optimal method provides an efficient yet flexible DDC solution to improve the experiences for ultra-compact ultrasound imaging system users.


Author(s):  
C J R Sheppard

The confocal microscope is now widely used in both biomedical and industrial applications for imaging, in three dimensions, objects with appreciable depth. There are now a range of different microscopes on the market, which have adopted a variety of different designs. The aim of this paper is to explore the effects on imaging performance of design parameters including the method of scanning, the type of detector, and the size and shape of the confocal aperture.It is becoming apparent that there is no such thing as an ideal confocal microscope: all systems have limitations and the best compromise depends on what the microscope is used for and how it is used. The most important compromise at present is between image quality and speed of scanning, which is particularly apparent when imaging with very weak signals. If great speed is not of importance, then the fundamental limitation for fluorescence imaging is the detection of sufficient numbers of photons before the fluorochrome bleaches.


Author(s):  
Seongwook Choi ◽  
Jin Young Kim ◽  
Hae Gyun Lim ◽  
Jin Woo Baik ◽  
Hyung Ham Kim ◽  
...  

2021 ◽  
Vol 15 ◽  
pp. 174830262110080
Author(s):  
Changjun Zha* ◽  
Qian Zhang* ◽  
Huimin Duan

Traditional single-pixel imaging systems are aimed mainly at relatively static or slowly changing targets. When there is relative motion between the imaging system and the target, sizable deviations between the measurement values and the real values can occur and result in poor image quality of the reconstructed target. To solve this problem, a novel dynamic compressive imaging system is proposed. In this system, a single-column digital micro-mirror device is used to modulate the target image, and the compressive measurement values are obtained for each column of the image. Based on analysis of the measurement values, a new recovery model of dynamic compressive imaging is given. Differing from traditional reconstruction results, the measurement values of any column of vectors in the target image can be used to reconstruct the vectors of two adjacent columns at the same time. Contingent upon characteristics of the results, a method of image quality enhancement based on an overlapping average algorithm is proposed. Simulation experiments and analysis show that the proposed dynamic compressive imaging can effectively reconstruct the target image; and that when the moving speed of the system changes within a certain range, the system reconstructs a better original image. The system overcomes the impact of dynamically changing speeds, and affords significantly better performance than traditional compressive imaging.


Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2858
Author(s):  
Kelly Ka-Lee Lai ◽  
Timothy Tin-Yan Lee ◽  
Michael Ka-Shing Lee ◽  
Joseph Chi-Ho Hui ◽  
Yong-Ping Zheng

To diagnose scoliosis, the standing radiograph with Cobb’s method is the gold standard for clinical practice. Recently, three-dimensional (3D) ultrasound imaging, which is radiation-free and inexpensive, has been demonstrated to be reliable for the assessment of scoliosis and validated by several groups. A portable 3D ultrasound system for scoliosis assessment is very much demanded, as it can further extend its potential applications for scoliosis screening, diagnosis, monitoring, treatment outcome measurement, and progress prediction. The aim of this study was to investigate the reliability of a newly developed portable 3D ultrasound imaging system, Scolioscan Air, for scoliosis assessment using coronal images it generated. The system was comprised of a handheld probe and tablet PC linking with a USB cable, and the probe further included a palm-sized ultrasound module together with a low-profile optical spatial sensor. A plastic phantom with three different angle structures built-in was used to evaluate the accuracy of measurement by positioning in 10 different orientations. Then, 19 volunteers with scoliosis (13F and 6M; Age: 13.6 ± 3.2 years) with different severity of scoliosis were assessed. Each subject underwent scanning by a commercially available 3D ultrasound imaging system, Scolioscan, and the portable 3D ultrasound imaging system, with the same posture on the same date. The spinal process angles (SPA) were measured in the coronal images formed by both systems and compared with each other. The angle phantom measurement showed the measured angles well agreed with the designed values, 59.7 ± 2.9 vs. 60 degrees, 40.8 ± 1.9 vs. 40 degrees, and 20.9 ± 2.1 vs. 20 degrees. For the subject tests, results demonstrated that there was a very good agreement between the angles obtained by the two systems, with a strong correlation (R2 = 0.78) for the 29 curves measured. The absolute difference between the two data sets was 2.9 ± 1.8 degrees. In addition, there was a small mean difference of 1.2 degrees, and the differences were symmetrically distributed around the mean difference according to the Bland–Altman test. Scolioscan Air was sufficiently comparable to Scolioscan in scoliosis assessment, overcoming the space limitation of Scolioscan and thus providing wider applications. Further studies involving a larger number of subjects are worthwhile to demonstrate its potential clinical values for the management of scoliosis.


Author(s):  
Kyuseok Kim ◽  
Hyun-Woo Jeong ◽  
Youngjin Lee

Vein puncture is commonly used for blood sampling, and accurately locating the blood vessel is an important challenge in the field of diagnostic tests. Imaging systems based on near-infrared (NIR) light are widely used for accurate human vein puncture. In particular, segmentation of a region of interest using the obtained NIR image is an important field, and research for improving the image quality by removing noise and enhancing the image contrast is being widely conducted. In this paper, we propose an effective model in which the relative total variation (RTV) regularization algorithm and contrast-limited adaptive histogram equalization (CLAHE) are combined, whereby some major edge information can be better preserved. In our previous study, we developed a miniaturized NIR imaging system using light with a wavelength of 720–1100 nm. We evaluated the usefulness of the proposed algorithm by applying it to images acquired by the developed NIR imaging system. Compared with the conventional algorithm, when the proposed method was applied to the NIR image, the visual evaluation performance and quantitative evaluation performance were enhanced. In particular, when the proposed algorithm was applied, the coefficient of variation was improved by a factor of 15.77 compared with the basic image. The main advantages of our algorithm are the high noise reduction efficiency, which is beneficial for reducing the amount of undesirable information, and better contrast. In conclusion, the applicability and usefulness of the algorithm combining the RTV approach and CLAHE for NIR images were demonstrated, and the proposed model can achieve a high image quality.


Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 861
Author(s):  
Elizabeth E. Niedert ◽  
Chenghao Bi ◽  
Georges Adam ◽  
Elly Lambert ◽  
Luis Solorio ◽  
...  

A microrobot system comprising an untethered tumbling magnetic microrobot, a two-degree-of-freedom rotating permanent magnet, and an ultrasound imaging system has been developed for in vitro and in vivo biomedical applications. The microrobot tumbles end-over-end in a net forward motion due to applied magnetic torque from the rotating magnet. By turning the rotational axis of the magnet, two-dimensional directional control is possible and the microrobot was steered along various trajectories, including a circular path and P-shaped path. The microrobot is capable of moving over the unstructured terrain within a murine colon in in vitro, in situ, and in vivo conditions, as well as a porcine colon in ex vivo conditions. High-frequency ultrasound imaging allows for real-time determination of the microrobot’s position while it is optically occluded by animal tissue. When coated with a fluorescein payload, the microrobot was shown to release the majority of the payload over a 1-h time period in phosphate-buffered saline. Cytotoxicity tests demonstrated that the microrobot’s constituent materials, SU-8 and polydimethylsiloxane (PDMS), did not show a statistically significant difference in toxicity to murine fibroblasts from the negative control, even when the materials were doped with magnetic neodymium microparticles. The microrobot system’s capabilities make it promising for targeted drug delivery and other in vivo biomedical applications.


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