scholarly journals Special Issue: Ti-Based Biomaterials: Synthesis, Properties and Applications

Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1696 ◽  
Author(s):  
Jarosław Jakubowicz

In the last half century, great attention has been paid to materials that can be used in the human body to prepare parts that replace failed bone structures. Of all materials, Ti-based materials are the most desirable, because they provide an optimum combination of mechanical, chemical and biological properties. The successful application of Ti biomaterials has been confirmed mainly in dentistry, orthopedics and traumatology. The Ti biomaterials provide high strength and a relatively low Young’s modulus. Titanium biocompatibility is practically the highest of all metallic biomaterials, however new solutions are being sought to continuous improve their biocompatibility and osseointegration. Thus, the chemical modification of Ti results in the formation of new alloys or composites, which provide new perspectives for Ti biomaterials applications. Great attention has also been paid to the formation of nanostructures in Ti-based biomaterials, which has leads to extremely good mechanical properties and very good biocompatibility. Additionally, the surface treatment applied to Ti-based biomaterials provides faster osseointegration and improve in many cases mechanical properties. The special issue “Ti-Based Biomaterials: Synthesis, Properties and Applications” has been proposed as a means to present recent developments in the field. The articles included in the special issue cover broad aspects of Ti-based biomaterials formation with respect to design theirs structure, mechanical and biological properties, as highlighted in this editorial.

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 61 ◽  
Author(s):  
Yannan Liu ◽  
Juan Gu ◽  
Daidi Fan

A novel, three-dimensional, porous, human-like collagen (HLC)/nano-hydroxyapatite (n-HA) scaffold cross-linked by 1,2,7,8-diepoxyoctane (DEO) was successfully fabricated, which showed excellent mechanical and superior biological properties for bone tissue regeneration in this study. The physicochemical characterizations of different n-HA/HLC/DEO (nHD) scaffolds were investigated by determining the morphology, compression stress, elastic modulus, Young’s modulus and enzymatic hydrolysis behavior in vitro. The results demonstrated that nHD-2 and nHD-3 scaffolds showed superior mechanical properties and resistance to enzymatic hydrolysis compared to nHD-1 scaffolds. The cell viability, live cell staining and cell adhesion analysis results demonstrated that nHD-2 scaffolds exhibited low cytotoxicity and excellent cytocompatibility compared with nHD-1 and nHD-3 scaffolds. Furthermore, subcutaneous injections of nHD-2 scaffolds in rabbits produced superior anti-biodegradation effects and histocompatibility compared with injections of nHD-1 and nHD-3 scaffolds after 1, 2 and 4 weeks. In addition, the repair of bone defects in rabbits demonstrated that nHD-2 scaffolds presented an improved ability for guided bone regeneration and reconstruction compared to commercially available bone scaffold composite hydroxyapatite/collagen (HC). Collectively, the results show that nHD-2 scaffolds show promise for application in bone tissue engineering due to their excellent mechanical properties, anti-biodegradation, anti-biodegradation, biocompatibility and bone repair effects.


2015 ◽  
Vol 1128 ◽  
pp. 105-111 ◽  
Author(s):  
Mădălina Simona Bălţatu ◽  
Petrică Vizureanu ◽  
Mircea Horia Tierean ◽  
Mirabela Georgiana Minciună ◽  
Dragoş Cristian Achiţei

Metallic biomaterials are used in various applications of the most important medical fields (orthopedic, dental and cardiovascular). The main metallic biomaterials are stainless steels, Co-based alloys and Ti-based alloys. Recently, titanium alloys are getting much attention for biomaterials because these types of materials have very good mechanical properties, good corrosion resistance and an excellent biocompatibility. The paper contains important information about titanium alloys used for biomedical applications, which are considered the most widely. It is very important to understand the microstructural evolution and property-microstructure relationship in implant alloys. In the present paper, authors present a short literature review on general aspects of promising biocompatible binary Ti-Mo alloys compared with CoCr and stainless steel alloys, as an alternative of the known metallic biomaterials. This alloys show superior mechanical compatibility and very good biocompatibility. The aim of this review is to highlight the mechanical properties for several types of biomaterials, their application in medical field, especially the Ti-Mo group.


Micromachines ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1447
Author(s):  
Madalina Simona Baltatu ◽  
Andrei Victor Sandu ◽  
Marcin Nabialek ◽  
Petrica Vizureanu ◽  
Gabriela Ciobanu

Over the last decade, researchers have been concerned with improving metallic biomaterials with proper and suitable properties for the human body. Ti-based alloys are widely used in the medical field for their good mechanical properties, corrosion resistance and biocompatibility. The TiMoZrTa system (TMZT) evidenced adequate mechanical properties, was closer to the human bone, and had a good biocompatibility. In order to highlight the osseointegration of the implants, a layer of hydroxyapatite (HA) was deposited using a biomimetic method, which simulates the natural growth of the bone. The coatings were examined by scanning electron microscopy (SEM), X-ray diffraction (XRD), micro indentation tests and contact angle. The data obtained show that the layer deposited on TiMoZrTa (TMZT) support is hydroxyapatite. Modifying the surface of titanium alloys represents a viable solution for increasing the osseointegration of materials used as implants. The studied coatings demonstrate a positive potential for use as dental and orthopedic implants.


2018 ◽  
Vol 19 (9) ◽  
pp. 2684 ◽  
Author(s):  
Amir Zadpoor

There has been a growing interest in metallic biomaterials during the last five years, as recent developments in additive manufacturing (=3D printing), surface bio-functionalization techniques, infection prevention strategies, biodegradable metallic biomaterials, and composite biomaterials have provided many possibilities to develop biomaterials and medical devices with unprecedented combinations of favorable properties and advanced functionalities. Moreover, development of biomaterials is no longer separated from the other branches of biomedical engineering, particularly tissue biomechanics, musculoskeletal dynamics, and image processing aspects of skeletal radiology. In this editorial, I will discuss all the above-mentioned topics, as they constitute some of the most important trends of research on metallic biomaterials. This editorial will, therefore, serve as a foreword to the papers appearing in a special issue covering the current trends in metallic biomaterials.


Materials ◽  
2020 ◽  
Vol 13 (20) ◽  
pp. 4668
Author(s):  
Radim Kocich ◽  
Lenka Kunčická

The research and development of modern metallic materials imparts not only the introduction of innovative alloys and compounds, but also the increasing lifetime of existing materials via optimized deformation processing. Among the essential features of progressive metallic materials used for modern applications are enhanced mechanical properties, but also other high-level functional characteristics, such as thermal–physical parameters, corrosion rate, and electric resistance. The properties of materials and alloys ensue from their structures, which can primarily be affected by the preparation/production process. The Special Issue “Mechanical Properties in Progressive Mechanically Processed Metallic Materials” was established to present recent developments and innovations particularly in the engineering field. The Special Issue comprises papers dealing with modern materials, such as metallic composites and pseudoalloys, as well as developments in various processing technologies.


2020 ◽  
Vol 2 (1) ◽  
pp. 50-55
Author(s):  
Gaurav Prashar ◽  
◽  
Hitesh Vasudev

The implant materials used currently in field of cardiovascular and orthopedics surgery dearth in osteoconductivity. Different surface modification techniques are used, developed and investigated over the years to enhance the osteoconductivity of biomaterials like metals, polymer and ceramics. Although implants made up of metals are strong mechanically but have low bonding ability due to bio-inert nature.To overcome the limitations and to accomplish the desired purpose, composite coatings consisting of bioactive are developed on the metallic biomaterials. In general bio-inert ceramics like yttria stabilized zirconia (ysz), titania, and alumina may be incorporated into hydroxyapatite (HA) matrix to develop composite coatings with improved mechanical properties over the years. The composite coatings developed by thermal spraying have shown promising approach to have good mechanical and biological properties in comparison with single-component and/or monolayer coatings. The strategy to use composite coatings is adopted widely by the professionals/scientists in the area of biomaterials for development and production of materials in order to repair and regeneration of the human tissue. In this article, commercially used thermal spraying techniques used for deposition of composite coatings for biomedical implants are discussed.


Author(s):  
Xiao Han ◽  
Yan Chen ◽  
Qian Jiang ◽  
Xin Liu ◽  
Yaming Chen

Secondary caries seriously limits the lifetime of composite resin. However, integrating all desirable properties (i.e., mechanical, antibacterial, bioactivity, and biocompatibility) into one composite resin is still challenging. Herein, a novel bioactive glass (BAG)-modified hybrid composite resin has been successfully developed to simultaneously achieve excellent mechanical properties, good biocompatibility, and antibacterial and remineralizing capabilities. When the mass fractions of BAG particles were added from 8 to 23 wt %, the original mechanical properties of the composite resin, including flexural strength and compressive strength, were not obviously affected without compromising the degree of conversion. Although the BAG incorporation of mass fractions of 16 wt % to 23 wt % in composite resins reduced cell viability, the viability could be recovered to normal by adjusting the pH value. Moreover, the BAG-modified composite resins that were obtained showed good antibacterial effects against Streptococcus mutans and enhanced remineralizing activity on demineralized dentin surfaces with increasing incorporation of BAG particles. The possible mechanisms for antibacterial and remineralizing activity might be closely related to the release of bioactive ions (Ca2+, Si4+), suggesting that its antibacterial and biological properties can be controlled by modulating the amounts of bioactive ions. The capability to balance the mechanical properties, cytotoxicity, antibacterial activity, and bioactivity makes the BAG-modified composite resin a promising prospect for clinical application. Our findings provide insight into better design and intelligent fabrication of bioactive composite resins.


2017 ◽  
Vol 8 (23) ◽  
pp. 3553-3559 ◽  
Author(s):  
Muzi Jing ◽  
Yang Fu ◽  
Xu Fei ◽  
Jing Tian ◽  
Hui Zhi ◽  
...  

A simple one-pot method was developed to fabricate a novel hydrogel with good biocompatibility, excellent mechanical properties, and identifiability via photopolymerization and sol–gel processes.


2020 ◽  
Vol 835 ◽  
pp. 243-250
Author(s):  
Ahmed Hamed ◽  
Mamdouh Eissa ◽  
Abdelhakim Kandil ◽  
Omnia Ali ◽  
Taha Mattar

Normalizing is an effective heat treatment in improving the microstructure and developing the mechanical properties of micro-alloyed steel. The normalizing parameters such as temperature and holding time are the main keys to microstructure and mechanical properties controlling. Therefore, obtaining an optimum combination of mechanical properties must be subjected to an ideal combination of these parameters. Furthermore, adjusting the optimum normalizing parameters must be considered for every chemical composition depending on the critical transformation temperatures. In this work, four micro-alloyed steel alloys containing V (0.008-0.1wt %) and Ti (0.002-0.072) were held on different normalizing temperatures for 30 minutes. The first holding temperature was carried out just above the Ac3 temperature and the second was carried out above the Ac3 by 100°C (Ac3+100°C). With the controlled normalizing condition, V-Ti-micro-alloyed steel alloy has produced an ultra-fine structure of grain size 2.2 microns and combined high strength of 725 MPa YS, 1058 MPa UTS and good ductility of 20%.


2021 ◽  
Vol 11 (15) ◽  
pp. 6914
Author(s):  
Ricardo Branco ◽  
Filippo Berto ◽  
Andrei Kotousov

Advanced high-strength steels play an essential role in many industries and engineering applications because of their excellent combination of mechanical properties important for design, e.g., strength, fatigue, fracture, wear, and manufacturability [...]


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