scholarly journals Design of Materials for Bone Tissue Scaffolds

Materials ◽  
2021 ◽  
Vol 14 (20) ◽  
pp. 5985
Author(s):  
Antonio Boccaccio
Keyword(s):  
Bone Tissue ◽  
Healing Time ◽  
Tissue Scaffolds ◽  
Crucial Importance ◽  
High Performing ◽  
The World ◽  
Implantation Process ◽  
Optimal Material ◽  
Object Of Study ◽  
Manufacturing Technologies

The strong impulse recently experienced by the manufacturing technologies as well as the development of innovative biocompatible materials has allowed the fabrication of high-performing scaffolds for bone tissue engineering. The design process of materials for bone tissue scaffolds represents, nowadays, an issue of crucial importance and the object of study of many researchers throughout the world. A number of studies have been conducted, aimed at identifying the optimal material, geometry, and surface that the scaffold must possess to stimulate the formation of the largest amounts of bone in the shortest time possible. This book presents a collection of 10 research articles and 2 review papers describing numerical and experimental design techniques definitively aimed at improving the scaffold performance, shortening the healing time, and increasing the success rate of the scaffold implantation process.

Hegels negative Dialektik

2020 ◽  
Vol 68 (3) ◽  
pp. 382-403
Author(s):  
Andreas Gelhard
Keyword(s):  
Radical Democracy ◽  
Crucial Importance ◽  
Phenomenology Of Spirit ◽  
Speculative Philosophy ◽  
The World ◽  
Pyrrhonian Skepticism ◽  
Negative Dialectic ◽  
Static Conditions ◽  
Practical Dimension ◽  
Pyrrhonian Scepticism

AbstractHegel’s approach to ancient scepticism is often discussed only in the context of epistemological questions. But it is also of crucial importance for his practical philosophy. Hegel draws on central figures of Pyrrhonian scepticism in order to subject Kant’s antinomies – i. e., Kant’s cosmology – to a fundamental revision. He radicalises Kant’s sceptical method to “self-completing scepticism”. At the same time he gives Kant’s concept of the world a practical twist: In Hegel’s Phenomenology of Spirit, world means an inhabited sphere in which powers and counter-powers are in conflict with each other. In doing so, he opens up the tradition of negativist thinking in political philosophy, which ranges from Marx and Adorno to the current theories of radical democracy. When Hegel calls Pyrrhonian skepticism a “negative dialectic”, he thereby marks what he views as a deficit: the inferiority of Pyrrhonian skepticism to speculative philosophy. However, it is precisely the practical dimension of Hegel’s dialectic that suggests that the sceptical motives of his thinking should be given great weight. This can be seen most clearly in Hegel’s concept of Bildung, which defines emancipation processes as the reactivation of open power relations in static conditions of domination.

scholarly journals LICENSED ANTHRAX VACCINES AND EXPERIMENTAL PREPARATIONS AT THE STAGE OF CLINICAL TRIALS

2017 ◽  
pp. 112-126
Author(s):  
N. I. Mikshis ◽  
P. Yu. Popova ◽  
A. P. Semakova ◽  
V. V. Kutyrev
Keyword(s):  
Clinical Trials ◽  
Russian Federation ◽  
Large Scale ◽  
Next Generation ◽  
The World ◽  
High Pathogenicity ◽  
The Russian Federation ◽  
Manufacturing Technologies ◽  
Anthrax Vaccines ◽  
Epidemiological Situation

High pathogenicity of anthrax agent combined with unique insensitivity of its spore forms to environmental stresses class it among extremely dangerous biological agents. Registered and effectively used anthrax vaccines made invaluable contribution to the improvement of epidemiological situation around the world. Nevertheless, neglect of non-specific prophylaxis may result in dramatic scenarios and require large-scale measures on rectification of the consequences. Efforts on the development of next-generation vaccines are aimed at safety build-up, decrease in frequency of administration, and enhancement of manufacturing technologies. The review contains the key information on licensed anthrax vaccines designed for medical use, both in the territory of the Russian Federation and abroad. Among multiple experimental developments emphasized have been preparations manufactured by various biopharmaceutical companies in compliance with GMP standards, at different phases of clinical trials in 2016.

scholarly journals Os Objetivos do Direito da Concorrência em Face da Ordem Econômica Nacional

2014 ◽  
Vol 9 (1) ◽  
Author(s):  
Luiz Carlos Buchain
Keyword(s):  
Economic Freedom ◽  
Market Failure ◽  
Market Competition ◽  
State Intervention ◽  
Perfect Competition ◽  
Economic Order ◽  
Economic Power ◽  
Free Enterprise ◽  
The World ◽  
Object Of Study

OS OBJETIVOS DO DIREITO DA CONCORRÊNCIA EM FACE DA ORDEM ECONÔMICA NACIONAL THE OBJECTIVES OF COMPETITION LAW REGARDING NATIONAL ECONOMIC ORDER Luiz Carlos Buchain RESUMO: A Constituição Federal brasileira, ao adotar o princípio da livre iniciativa para a Ordem Econômica, também acatou a liberdade de empresa como fundamento destinado a estabelecer a ampla concorrência de mercado entre agentes econômicos. Entretanto, como demonstra a história econômica, a liberdade econômica traz em si a concentração de poder econômico nas mãos de determinadas empresas (ou grupo). Tal concentração de poder é considerada uma das falhas de mercado porque possibilita ao seu detentor adotar determinados comportamentos prejudiciais à concorrência, os quais não seriam factíveis na ausência desse poder. Por isso mesmo, a concentração e o poder econômico passaram a ser objeto de estudos jurídicos e econômicos baseados na premissa de que a preservação da livre concorrência é um pressuposto ao desenvolvimento da economia e garantia da livre iniciativa. O direito econômico reconhece que a livre iniciativa, isoladamente considerada, não garante a manutenção da liberdade econômica ou o modelo de competição perfeita no mundo fático, ou seja, os modelos econômicos estão sujeitos a falhas estruturais cuja correção justifica a intervenção do Estado na economia. Neste artigo, abordamos as diversas correntes que defendem ou condenam a intervenção do estado na economia e sua regulação, em variados graus. A intervenção do Estado na economia tornou-se objeto de estudo e matéria legislativa em todo o mundo, seja na ordem legislativa interna, seja na esfera do direito público internacional, donde se destaca a Organização Mundial do Comércio – OMC e a Organização para a Cooperação e Desenvolvimento Econômico – OCDE. PALAVRAS-CHAVE: Concorrência; Objetivos; Livre iniciativa; Regulação. ABSTRACT: The Brazilian Federal Constitution, once it adopted the principle of free enterprise for its economic order, also accepted the freedom to conduct a business as the basis for the establishment of the broader market competition among economic agents. However, as economic history shows, economic freedom brings with itself concentration of economic power in the hands of certain companies (or group of companies). Such a concentration of power is reputed a market failure derives because it enables such companies to adopt certain behaviors considered harmful to competition, which would not be feasible without such power. Therefore, concentration and economic power have become object of study of law and economics based on the premise that the preservation of free competition is an assumption for the economic development and guarantee of free enterprise. Economic law recognizes as a fact that free enterprise, taken in isolation, does not guarantee the sustenance of economic freedom or the model of perfect competition in the factual world; in other words, economic models are subject to structural failures whose correction justifies state intervention in economy. In this paper we discuss the various currents that advocate or condemn state intervention in the economy and its regulation, in varying degrees. State intervention in the economy has become the object of study and legislative matters in the world, whether in the internal legislative order or in the sphere of public international law, where stands the World Trade Organization – WTO and the Organization for Economic Co-operation and Development - OECD.KEYWORDS: Competition; Objectives; Free enterprise; Regulation. SUMÁRIO: Introdução. 1. O direito da concorrência e as políticas públicas. 1.1. Principais objetivos da política de concorrência. 1.2. Objetivos complementares da política de concorrência. 2. Interface entre política de concorrência e outras políticas públicas. 2.1. Possíveis conflitos entre múltiplos objetivos. 2.2. Instrumentos da política de concorrência. Considerações finais. Referências.

scholarly journals NATURAL HISTORY MUSEUMS

2021 ◽  
pp. 24-28
Author(s):  
Dimítri De Araújo Costa ◽  
Nuno Gomes ◽  
Harold Cantallo ◽  
Carlos Antunes
Keyword(s):  
Natural History ◽  
Public Awareness ◽  
Natural World ◽  
Scientific Culture ◽  
Natural History Museums ◽  
Type Specimens ◽  
Local Fauna ◽  
History Museums ◽  
The World ◽  
Object Of Study

Society in general is distant from scientific culture, it is required to bring scientific knowledge closer to the population. In this context, an effective and attractive way for scientific dissemination is the establishment of natural history museums, which are institutions of knowledge, displaying the past. Natural history museums have the natural world as their object of study; and their collections may contain the most diverse types of materials (local and/or from various parts of the world), such as zoological, botanical, geological, archaeological, among others. Scientific collections are the largest and most important source of authoritative biodiversity data, contributing to studies of biodiversity composition, evolutionary (morphological and genetic), biogeographical, phenological, as well as geological. The materials present in these collections may serve for temporal comparison, being useful to produce predictive models. Likewise, they have a fundamental role in safeguarding type specimens, i.e. the first organisms identified to describe and name a new species. In addition, there is the component available to visitors in general, in order to raise public awareness on the preservation of the local fauna and flora and of other places in the world. In this way, the museums serve both the academic-scientific public and visitors who come to these sites for recreational purposes. It is intended to promote, in Vila Nova de Cerveira, the Natural History Museum of the Iberian Peninsula - NatMIP (“Museu de História Natural da Península Ibérica”), which intends to collect materials for scientific purposes, mainly Iberian.

scholarly journals Performance of the national fencing team of Ukraine at the XXXII Olympic Games and the prospects of its performance at the next Olympic Games

2021 ◽  
pp. 84-87
Author(s):  
Olga Kuvaldina ◽  
Volodymyr Driukov
Keyword(s):  
Olympic Games ◽  
Crucial Importance ◽  
Team Members ◽  
National Team ◽  
Sports Events ◽  
The World ◽  
High Level ◽  
Sports Statistics ◽  
Stimulation Of ◽  
The Olympic Games

Analysis of Ukrainian athletes’ results at the XXXII Olympiad Games allows pointing out the factors of the weak performance of Ukrainian athletes in women's individual saber and epee competitions, as well as men's team epee competitions, despite the possibility of winning medals in these sports events according to many analysts including those of Infostrada Sports and other sports statistics experts. These, in our opinion, include an unsatisfactory level of efficiency of the process of reaching the peak of readiness for the Olympic Games; lack of psychological stability of athletes at the competitions; weak tactical preparation of some athletes. Based on the performances of athletes of the Ukrainian fencing team in Tokyo, a conclusion was made about the unsatisfactory level of athletes’ preparation for the XXXII Olympic Games. Only 20% of the national team members were able to realize their potential at the XXXII Olympic Games. The dynamics of the athletes’ results at the World Championships 2017 – 2019 indicates the need to use in the new Olympic cycle the planning, which is focused on our athletes reaching the peak of readiness for the Olympics: at first, the training should be aimed at the maximum stimulation of the growth of sportsmanship, whereas at the final stage it should be focused on its realization in the major competitions. It is shown that despite the unsuccessful performance of the Ukrainian fencing team in the Olympic Tokyo, this type of martial arts has significant potential for improving sports achievements at the XXXIII Olympic Games 2024 in Paris. It is noted that in the new Olympic cycle it is of crucial importance to identify candidates for the XXXIII Olympic Games as soon as possible and to create all the conditions for their full-fledged preparation. Thus, to ensure further winning medal places at the Olympic Games, it is necessary to improve the system of sports training in the Olympic cycle, which envisages participation in numerous competitions during the year to achieve a high level of readiness in the major competitions of triennial – the Olympic Games.

scholarly journals East in the Creative Mind of B. Volkov

2021 ◽  
Vol 17 (1) ◽  
pp. 264-280
Author(s):  
E. N. Proskurina ◽  
Keyword(s):  
San Francisco ◽  
The Novel ◽  
Lao Tzu ◽  
Creative Mind ◽  
Life And Death ◽  
The World ◽  
Object Of Study

The article is devoted to the images and motives of the East in the poetry of the author of the Eastern emigration Boris Volkov (1894, Ekaterinburg – 1954, San Francisco). The work of this poet, writer, publicist is still unknown to the domestic reader, although during his lifetime he had a fairly wide publication geography: from Harbin to San Francisco. However, his works were never reprinted, and the manuscript of the novel “The Kingdom of the Golden Buddhas” is considered lost. The analysis involved Volkov’s book of poems “In the dust of foreign roads”, published in Berlin in 1934. Of its four parts, the oriental flavor is especially distinct in the first. Individual works of this part constituted the object of study of this article. The autobiographical substrate of Volkov’s poetry is revealed, the intersection of motives and imagery with the poetic world of Gumilyov is shown. The influence of the Eastern world, its philosophical teachings on the creative worldview of Volkov is investigated. In his poetic thinking, traces of Sufism, Islam, and the philosophy of Lao Tzu are palpable. Exotic images of China and Mongolia weave an intricate pattern in the first cycles of the book, integrating into the depicted biographical circumstances and expanding their semantic palette. “Alien” is trying hard to become “ours” at the level of a philosophical attitude to the world and the fate of the poet himself. He is close to the poetic attitude of the inhabitants of the East to life and death, based on ancient traditions and customs. The poems reflect the confusion of the experiences of the lyrical hero, warrior and wanderer, who has found a place in life as a result of an action-packed duel with fate.

scholarly journals Augmented Reality and the Prospects for Applying Its in the Training of Future Engineers

2018 ◽  
Vol 51 ◽  
pp. 247-254
Author(s):  
Наталія Рашевська ◽  
Володимир Соловйов
Keyword(s):  
Augmented Reality ◽  
Research Method ◽  
Technical School ◽  
The World ◽  
System Components ◽  
The Subject ◽  
Object Of Study ◽  
Intellectual Potential ◽  
The Impact ◽  
Interdisciplinary Integration

Rashevska N.V. and Soloviev V.N. Augmented Reality and the Prospects for Applying Its in the Training of Future Engineers. The education system of Ukraine is closely linked with the world education trends, therefore it requires constant renewal and expansion. One of the progressive areas of organizing studying process is creating the studying environment which will allow students to reveal their intellectual potential while searching for the necessary knowledge. That’s why the purpose of the article is analysis of the concept of augmented reality and prospects of its application in the process of training future engineers. The object of study is the system of training future engineers and the subject is using of augmented reality technologies in the process of training future engineers. The research method is analyzing the impact of the augmented reality technologies on the training future engineers. During the research, we have identified positive aspects of the augmented reality technologies in the process of training future engineers. We have defined the stages of creating some methodical system components of teaching fundamental disciplines in the higher technical school through interdisciplinary integration and technologies of augmented reality.  

scholarly journals THE RESEARCH OF SENTENCE LENGTH, WORDS AND PERIODICITY OF WORD FORMS IN THE COLLECTIONS OF PETRO KARMANSKY

2020 ◽  
Vol 11 (87) ◽  
Author(s):  
Liliia Solovei ◽  
Keyword(s):  
Statistical Analysis ◽  
Standard Deviation ◽  
Sentence Length ◽  
Creative Work ◽  
Maximum Value ◽  
The World ◽  
Word Forms ◽  
Object Of Study ◽  
Individual Style ◽  
Linguistic Means

This work researched the linguostatistical indicators of poetic works of P. Karmansky, in particular the lengths of sentences, words and word forms are comprehensively calculated and analyzed. The following values that characterize the poet’s idiostyle are calculated: the number of values (n); maximum value (max); minimum value (min); scope (R); fashion (Mo); median (Md); average (X ̇); standard deviation (σ); coefficient of variation (V); standard error (Sx ̇); relative error (ε). The main object of study of the writer’s idiostyle is the language of his works of art, the set of linguistic means that decide the artist as an individual among others. The unified basis of all units of idiosyncrasy is the author’s worldview. Therefore, the problem of studying individual style is closely related to the problems of the linguistic picture of the world and the linguistic personality of the writer. P. Karmansky’s poetry is an interesting and little-studied phenomenon in Ukrainian literature. In listening to a number of researchers considered the life of P. Karmansky, separately thematic work, characterized by the peculiarities of those who compose his poetics. Instead, the creative work of P. Karmansky did not become the object of linguistic and statistical analysis, which determines the relevance and novelty of the study. The research corpus systematizes the author's poetry is systematized on the basis of his collections, publications in contemporary periodicals and manuscripts. The material of the study was the texts of Petro Karmansky’s collection «Poeziyi», published in Kyiv by «Ukrayinskyy pysmennyk» in 1992, which is considered one of the most complete collections, containing previously unpublished poems (the total number of poems in this collection - 334). The analysis showed that Karmansky used to use sentences of four words and words of four letters. The list of the nine most common word forms that appeared in Karmansky’s selected poems is «і» – 1714 times, «в» – 1157 times, «не» – 605 разів, «з» – 532, «на» – 507, «що» – 461, «як» – 429, «я» – 326, «а» – 207. It turns out how the poetic handwriting of the artist changed during his life.It turns out how the poetic handwriting of the artist changed during his life.

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