scholarly journals Preservation of Mimosa tenuiflora Antiaflatoxigenic Activity Using Microencapsulation by Spray-Drying

Molecules ◽  
2022 ◽  
Vol 27 (2) ◽  
pp. 496
Author(s):  
Christopher Hernandez ◽  
Laura Cadenillas ◽  
Céline Mathieu ◽  
Jean-Denis Bailly ◽  
Vanessa Durrieu
Keyword(s):  
Spray Drying ◽  
Aqueous Extract ◽  
Room Temperature ◽  
Biological Activities ◽  
Total Phenolic ◽  
Environmental Interactions ◽  
Wall Materials ◽  
One Year ◽  
Better Than ◽  
Mimosa Tenuiflora

Mimosa tenuiflora aqueous extract (MAE) is rich in phenolic compounds. Among them, condensed tannins have been demonstrated to exhibit a strong antioxidant and antiaflatoxin B1 activities in Aspergillus flavus. Since antioxidant capacity can change with time due to environmental interactions, this study aimed to evaluate the ability of encapsulation by spray-drying of Mimosa tenuiflora aqueous extract to preserve their biological activities through storage. A dry formulation may also facilitate transportation and uses. For that, three different wall materials were used and compared for their efficiency. Total phenolic content, antioxidant activity, antifungal and antiaflatoxin activities were measured after the production of the microparticles and after one year of storage at room temperature. These results confirmed that encapsulation by spray-drying using polysaccharide wall materials is able to preserve antiaflatoxin activity of Mimosa tenuiflora extract better than freezing.

scholarly journals Influence of Spray-Drying and Room Temperature Storage on the Anti- and Prooxidant Properties of Fermented Juçara Pulp

2020 ◽  
Vol 58 (1) ◽  
pp. 29-37
Author(s):  
Karla Bigetti Guergoletto ◽  
Kamila Landucci Bonifácio ◽  
Décio Sabbatini Barbosa ◽  
Daniel Farinha Valezi ◽  
Aroldo Salviato ◽  
...  
Keyword(s):  
Free Radicals ◽  
Free Radical ◽  
Antioxidant Capacity ◽  
Spray Drying ◽  
Room Temperature ◽  
Gum Arabic ◽  
Radical Formation ◽  
Total Phenolic ◽  
Free Radical Formation ◽  
And Storage

Many fruits and vegetables contain compounds with antioxidant properties, but the processing and storage conditions of the food industry may damage these beneficial compounds and produce free radicals that are associated with oxidative stress. This study aims to evaluate in vitro the antioxidant capacity and prooxidant effects of juçara pulp fermented with Lactobacillus reuteri or Lactobacillus plantarum before and after spray-drying with maltodextrin, gum arabic or gelatin and storage at 25 °C for 90 days. The antioxidant capacity was assessed by measuring the ability to scavenge reactive oxygen species (ROS) in the neutrophil respiratory burst and free radical 2,2-diphenyl-1-picryl-hydrazyl (DPPH), and by determining the total phenolic content. The prooxidant effects were analyzed as free radical formation measured by electronic paramagnetic resonance (EPR). Fermentation by both bacteria increased the antioxidant activity, while the spray-drying process decreased the content of phenolic compounds (65-85 %) and the DPPH scavenging ability, depending on the carrier usage. All of the samples inhibited ROS in the neutrophil burst, and the juçara pulp fermented by L. reuteri and dried with gum arabic exhibited the best performance. Spray-drying did not influence the intensity or type of free radicals detected by EPR. However, storage at room temperature decreased the antioxidant capacity and increased free radical formation.

scholarly journals EVALUATION OF BIOLOGICAL ACTIVITIES AND STABILITY OF THAI ORGANIC RICEBERRY BROKEN RICE EXTRACTS FOR THE ANTI-AGING COSMETOLOGY

2021 ◽  
pp. 1-4
Author(s):  
WORRAPAN POOMANEE ◽  
PIMJAI DOUNGSAARD ◽  
NARA NANTHARAT ◽  
PIMPORN LEELAPORNPISID
Keyword(s):  
Spray Drying ◽  
Ph Value ◽  
Biological Activities ◽  
Total Phenolic ◽  
Antioxidant Power ◽  
Broken Rice ◽  
Ferric Reducing Antioxidant Power ◽  
The Stability ◽  
Nutritional Benefits ◽  
Antioxidant Effects

Objective: Thai organic Riceberry rice, deep purple rice, has been known to have the wide variety of nutritional benefits. However, broken rice whichaccounted for 20-30% of the yield, was sold at a very low price. This study aimed to optimize the extracting procedure and evaluate the biologicalactivities of Thai organic Riceberry broken rice extracts for anti-aging cosmetology as well as to investigate the stability profile of the extract.Methods: The extracting procedure, of which deionized water served as a solvent, was varied by spray-drying temperature (150 and 170°C)and pH value (2.0 and 5.5). Antioxidant effects of the obtained extracts were evaluated through 2,2-Diphenyl-1-picrylhydrazyl, 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid, linoleic acid peroxidation, and ferric reducing antioxidant power assays. Furthermore, the anti-tyrosinaseeffect was studied through the L-tyrosine pathway. The total phenolic content (TPC) of each extract was evaluated by Folin–ciocalteu’s method. Theextract, presenting the greatest activity, was then selected for investigating its stability under various storage conditions.Results: Four Riceberry rice extracts presented noticeable antioxidant and anti-tyrosinase effect. The extract, derived from a spray-drying temperatureof 150°C and a pH value of 2.0, exhibited the highest effects with the highest TPC (27.08 ± 0.67 mg Gallic acid/g extract). This extract also presented agood stability profile. However, this extract should be stored in a high-temperature condition (45°C) to prevent degradation.Conclusion: The aqueous extracts of Thai organic Riceberry broken rice could be a promising agent for further developing into anti-aging cosmetology.

scholarly journals Characterization of Oregano Essential Oil (Origanum vulgare L. subsp. hirtum) Particles Produced by the Novel Nano Spray Drying Technique

Foods ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2923
Author(s):  
Fotini Plati ◽  
Rigini Papi ◽  
Adamantini Paraskevopoulou
Keyword(s):  
Essential Oil ◽  
Spray Drying ◽  
Encapsulation Efficiency ◽  
Biological Activities ◽  
Antibacterial Properties ◽  
Spherical Shape ◽  
Partial Replacement ◽  
Structural Stabilization ◽  
Oregano Essential Oil ◽  
Wall Materials

Oregano essential oil (OEO), due to its wide variety of biological activities, could be a “green” alternative to chemical preservatives. On the other hand, the difficulties in its use or storage have turned researchers’ interest in encapsulation strategies as a way to face stability and handling issues. Fabrication of OEO-loaded particles, using nano spray drying technique (NSD) and whey protein isolate-maltodextrin mixtures (1:1, 1:3) as wall materials appears to be a novel and promising strategy. The obtained particles were characterized in terms of volatile composition, encapsulation efficiency, and physicochemical, molecular, morphological, and antibacterial properties. The results confirmed that encapsulation of OEO using NSD achieved high levels of powder recovery (>77%) and encapsulation efficiency (>98%) while assisting in the retention of the main bioactive compounds. The partial replacement of WPI by MD significantly affected particles’ physical properties. FTIR analyses revealed the possible structural stabilization of core and wall materials, while SEM verified the very fine size and spherical shape. Finally, antibacterial studies demonstrated their activity against Escherichia coli and Staphylococcus aureus, which is much stronger in comparison with that of pure OEO, proving the positive effect of NSD and particles’ potential in future food applications.

In Vitro Evaluation of Biological Activities of Silver Nanoparticles Synthesized Using Dalbergia rostrata Stem Bark

2014 ◽  
Vol 2 ◽  
pp. 194308921350703 ◽  
Author(s):  
N. Muniyappan ◽  
N. S. Nagarajan
Keyword(s):  
Aqueous Solution ◽  
Silver Nanoparticles ◽  
Aqueous Extract ◽  
Biomedical Applications ◽  
Room Temperature ◽  
Biological Activities ◽  
Stem Bark ◽  
Transmission Electron ◽  
Uv Visible

Silver nanoparticles (AgNPs) synthesized are utilized in drugs because of their pharmacological and biomedical applications and also due to their ecofriendly properties. In the present study, stable AgNPs have been synthesized from the aqueous extract of Dalbergia rostrata stem bark (DRSB), which is used both as a reducing and as a stabilizing agent. The AgNPs synthesized by ultrasonication at 25°C for 10 min were found to be stable in aqueous solution at room temperature over a period of 3 months. The quantitatively stable AgNPs formed by treating the aqueous solution of AgNO3 with the aqueous extract of the plant by reduction of Ag+ ions when monitored by UV–visible spectroscopic study revealed the surface plasmon resonance (SPR) at 425 nm. According to transmission electron micrography, the NPs were spherical and in the size range of 14 ± 4 nm. When evaluated for their anti-inflammatory and antioxidant activity by in vitro methods, AgNPs showed considerably enhanced activity compared to DRSB aqueous extract.

Room Temperature Flow Electrochemistry as a Means of Retaining the “Memory of Chirality” via Hofer Moest Type Reaction

2020 ◽  
Author(s):  
Tomas Hardwick ◽  
Rossana Cicala ◽  
Nisar Ahmed
Keyword(s):  
Continuous Flow ◽  
Room Temperature ◽  
Biological Activities ◽  
Supporting Electrolyte ◽  
Enantiomeric Excess ◽  
Flow Chemistry ◽  
Batch Processes ◽  
Enabling Technology ◽  
Chiral Compounds ◽  
Memory Of Chirality

<p>Many chiral compounds have become of great interest to the pharmaceutical industry as they possess various biological activities. Concurrently, the concept of “memory of chirality” has been proven as a powerful tool in asymmetric synthesis, while flow chemistry has begun its rise as a new enabling technology to add to the ever increasing arsenal of techniques available to the modern day chemist. Here, we have employed a new simple electrochemical microreactor design to oxidise an L-proline derivative at room temperature in continuous flow. Flow performed in microreactors offers up a number of benefits allowing reactions to be performed in a more convenient and safer manner, and even allow electrochemical reactions to take place without a supporting electrolyte due to a very short interelectrode distance. By the comparison of electrochemical oxidations in batch and flow we have found that continuous flow is able to outperform its batch counterpart, producing a good yield (71%) and a better enantiomeric excess (64%) than batch with a 98% conversion. We have, therefore, provided evidence that continuous flow chemistry has the potential to act as a new enabling technology to replace some aspects of conventional batch processes. </p>

The Role of Chess in the Intellectual Development of Childrens from Primary School

2019 ◽  
pp. 58-62
Author(s):  
Vlad Stegariu ◽  
Simona Andreea Popușoi ◽  
Beatrice Abălașei ◽  
Nicolae Lucian Voinea ◽  
Ioan Stelescu ◽  
...  
Keyword(s):  
Cognitive Development ◽  
Primary School ◽  
Intellectual Development ◽  
Resources Allocation ◽  
Control Group ◽  
Cognitive Resources ◽  
One Year ◽  
Better Than ◽  
Chess Playing

Chess playing has a significant role in participants’ resources allocation, both at a psychological level, but mostly concerning the cognitive resources. The aim of the present study was to examine the effect of chess playing on the intellectual development of primary-class students. 67 children were tested using the Raven Standard Progressive Matrices and were distributed in three different groups according to their experience with chess, namely: the control group (formed by students with no experience with chess playing), the beginners group (students with less than one year in chess playing training) and the advanced group (children with more than two years experience with chess). Results indicated that chess playing had a significant effect on the SPM performance, indicating that those in the advanced group performed significantly better than those in the control or in the beginners group. Conclusions of this study tap into the benefits of playing chess with a focus on the children’s’ cognitive development.

scholarly journals Mimosa tenuiflora Aqueous Extract: Role of Condensed Tannins in Anti-Aflatoxin B1 Activity in Aspergillus flavus

Toxins ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 391
Author(s):  
Christopher Hernandez ◽  
Laura Cadenillas ◽  
Anwar El Maghubi ◽  
Isaura Caceres ◽  
Vanessa Durrieu ◽  
...  
Keyword(s):  
Aspergillus Flavus ◽  
Aqueous Extract ◽  
Aflatoxin B1 ◽  
Condensed Tannins ◽  
Fungal Growth ◽  
Oxidation Reactions ◽  
Expression Of Genes ◽  
Dependent Inhibition ◽  
Interesting Candidate ◽  
Mimosa Tenuiflora

Aflatoxin B1 (AFB1) is a potent carcinogenic mycotoxin that contaminates numerous crops pre- and post-harvest. To protect foods and feeds from such toxins without resorting to pesticides, the use of plant extracts has been increasingly studied. The most interesting candidate plants are those with strong antioxidative activity because oxidation reactions may interfere with AFB1 production. The present study investigates how an aqueous extract of Mimosa tenuiflora bark affects both the growth of Aspergillus flavus and AFB1 production. The results reveal a dose-dependent inhibition of toxin synthesis with no impact on fungal growth. AFB1 inhibition is related to a down-modulation of the cluster genes of the biosynthetic pathway and especially to the two internal regulators aflR and aflS. Its strong anti-oxidative activity also allows the aqueous extract to modulate the expression of genes involved in fungal oxidative-stress response, such as msnA, mtfA, atfA, or sod1. Finally, a bio-guided fractionation of the aqueous extract demonstrates that condensed tannins play a major role in the anti-aflatoxin activity of Mimosa tenuiflora bark.

scholarly journals Optimization of Natural Antioxidants Extraction from Pineapple Peel and Their Stabilization by Spray Drying

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1255
Author(s):  
Sofia C. Lourenço ◽  
Débora A. Campos ◽  
Ricardo Gómez-García ◽  
Manuela Pintado ◽  
M. Conceição Oliveira ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
Spray Drying ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Food Products ◽  
Total Phenolic ◽  
Dry Extract ◽  
Pineapple Peel ◽  
Dpph Method

Pineapple peel still contains an important amount of phenolic compounds and vitamins with valuable antioxidant activity. In this way, the aim of this study was the recovery of the bioactive compounds from pineapple peel using environmentally friendly and low-cost techniques, envisaging their application in food products. From the solid-liquid extraction conditions tested, the one delivering an extract with higher total phenolic content and antioxidant capacity was a single extraction step with a solvent-pineapple peel ratio of 1:1 (w/w) for 25 min at ambient temperature, using ethanol-water (80–20%) as a solvent. The resulting extract revealed a total phenolic content value of 11.10 ± 0.01 mg gallic acid equivalent (GAE)/g dry extract, antioxidant activity of 91.79 ± 1.98 µmol Trolox/g dry extract by the DPPH method, and 174.50 ± 9.98 µmol Trolox/g dry extract by the FRAP method. The antioxidant rich extract was subjected to stabilization by the spray drying process at 150 °C of inlet air temperature using maltodextrin (5% w/w) as an encapsulating agent. The results showed that the antioxidant capacity of the encapsulated compounds was maintained after encapsulation. The loaded microparticles obtained, which consist of a bioactive powder, present a great potential to be incorporated in food products or to produce bioactive packaging systems.

scholarly journals Novel technology for storage and distribution of live vaccines and other biological medicines at ambient temperature

2020 ◽  
Vol 6 (10) ◽  
pp. eaau4819 ◽  
Author(s):  
Irnela Bajrovic ◽  
Stephen C. Schafer ◽  
Dwight K. Romanovicz ◽  
Maria A. Croyle
Keyword(s):  
Room Temperature ◽  
Recombinant Adenovirus ◽  
Amorphous Solid ◽  
Live Virus ◽  
Live Vaccines ◽  
Novel Technology ◽  
Production Distribution ◽  
Global Access ◽  
Reducing Costs ◽  
Better Than

A novel, thin-film platform that preserves live viruses, bacteria, antibodies, and enzymes without refrigeration for extended periods of time is described. Studies with recombinant adenovirus in an optimized formulation that supports recovery of live virus through 16 freeze-thaw cycles revealed that production of an amorphous solid with a glass transition above room temperature and nitrogen-hydrogen bonding between virus and film components are critical determinants of stability. Administration of live influenza virus in the optimized film by the sublingual and buccal routes induced antibody-mediated immune responses as good as or better than those achieved by intramuscular injection. This work introduces the possibility of improving global access to a variety of medicines by offering a technology capable of reducing costs of production, distribution, and supply chain maintenance.

scholarly journals One-pot green synthesis of gold and silver nanoparticles using Rosa canina L. extract

RSC Advances ◽  
2021 ◽  
Vol 11 (24) ◽  
pp. 14624-14631
Author(s):  
Pablo Eduardo Cardoso-Avila ◽  
Rita Patakfalvi ◽  
Carlos Rodríguez-Pedroza ◽  
Xochitl Aparicio-Fernández ◽  
Sofía Loza-Cornejo ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Aqueous Extract ◽  
Room Temperature ◽  
One Pot ◽  
Gold And Silver Nanoparticles ◽  
Rosa Canina ◽  
Capping Agents

Gold and silver nanoparticles were synthesized at room temperature using an aqueous extract from dried rosehips acting as reducing and capping agents with no other chemicals involved.

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