scholarly journals Regenerative Potential of Enamel Matrix Protein Derivative and Acellular Dermal Matrix for Gingival Recession: A Systematic Review and Meta-Analysis

Proteomes ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 11
Author(s):  
Muhammad Saad Shaikh ◽  
Mohid Abrar Lone ◽  
Hesham Matabdin ◽  
Muneeb Ahmed Lone ◽  
Azeem Hussain Soomro ◽  
...  
Keyword(s):  
Matrix Protein ◽  
Meta Analysis ◽  
Acellular Dermal Matrix ◽  
Gingival Recession ◽  
Enamel Matrix ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Keratinized Tissue ◽  
Enamel Matrix Protein ◽  
Acellular Dermal

Objective: The purpose of this study was to assess the clinical effectiveness of using a combination of enamel matrix protein derivative and acellular dermal matrix in comparison to acellular dermal matrix alone for treating gingival recessions. Methods: The Cochrane Library (Wiley), PubMed by Medline (NLM), Medline (EBSCO), and Embase (Ovid) databases were searched for entries up to April 2020. Only clinical trials were included. Primary outcomes were root coverage (%), changes in keratinized tissue width and recession (mm). Meta-analysis was conducted for root coverage, changes in keratinized tissue width, recession, clinical attachment level and probing depth. Results: Four studies were selected for the analysis. In primary outcomes, root coverage, change in keratinized tissue width and recession analysis showed a mean difference of 4.99% (p = 0.11), 0.20 mm (p = 0.14) and 0.13 mm (p = 0.23) respectively between the two groups. Secondary outcomes analysis also exhibited a statistically insignificant difference between the test and control group with mean difference of 0.11 mm (p = 0.32) in clinical attachment level gain and -0.03 mm (p = 0.29) in probing depth reduction analysis. Conclusions: Within the limits of this study, enamel matrix protein derivative combined with acellular dermal matrix used for treating gingival recession defects resulted in no beneficial effect clinically than acellular dermal matrix only.

scholarly journals ROOT COVERAGE USING THE SUBEPITHELIAL CONNECTIVE TISSUE GRAFT OR THE ACELLULAR DERMAL MATRIX FOR THE TREATMENT OF GINGIVAL RECESSION: A CLINICAL STUDY

2018 ◽  
Vol 9 ◽  
pp. 20
Author(s):  
Shula Zuleika Sumana ◽  
Sri Lelyati C Masulili ◽  
Robert Lessang
Keyword(s):  
Connective Tissue ◽  
Acellular Dermal Matrix ◽  
Gingival Recession ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Connective Tissue Graft ◽  
Tissue Graft ◽  
Operative Data ◽  
Subepithelial Connective Tissue Graft ◽  
Acellular Dermal

Objective: This study aims to evaluate periodontal clinical conditions after treatment for gingival recession (GR) using subepithelial connective tissue graft (SCTG) and acellular dermal matrix (ADM).Methods: Ten patients with Miller’s Class I and II recessions that had been treated with SCTG or ADM at the Periodontics Outpatient Department at Universitas Indonesia were selected for this study. The pre-operative data for GR, clinical attachment levels (CAL), and attached gingiva (AG) were retrieved from the patients’ medical records. The patients were recalled and the post-operative data were recorded.Results: The application of SCTG and ADM yields significant changes to GR, CAL, and AG levels. A comparison of two groups at the post-operative assessment stage showed no statistically significant differences, in terms of GR, CAL, and AG.Conclusion: SCTG and ADM yield similar outcomes in the treatment of GR. As such, ADM may be suggested as an alternative to SCTG for root coverage.

A Comparative Study of Root Coverage Using Acellular Dermal Matrix With and Without Enamel Matrix Derivative

2007 ◽  
Vol 78 (3) ◽  
pp. 411-421 ◽  
Author(s):  
Sang Ho Shin ◽  
Marco A. Cueva ◽  
David G. Kerns ◽  
William W. Hallmon ◽  
Francisco Rivera-Hidalgo ◽  
...  
Keyword(s):  
Comparative Study ◽  
Acellular Dermal Matrix ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Acellular Dermal ◽  
Matrix Derivative

scholarly journals Clinical evaluation of root coverage using coronally positioned flap associated with acellular dermal matrix allograft in single-type recession defects. A retrospective study

2021 ◽  
Vol 34 (2) ◽  
pp. 136-142
Author(s):  
Guillermo Schinini ◽  
Alessia Molinari ◽  
Hugo Romanelli
Keyword(s):  
Retrospective Study ◽  
Donor Site ◽  
Acellular Dermal Matrix ◽  
Single Type ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Keratinized Tissue ◽  
Probing Depth ◽  
Clinical Records ◽  
Acellular Dermal

The aim of this study was to conduct a retrospective assessment of the clinical results at 6,12 and 24 months of root coverage in single gingival recessions using coronally positioned flap and acellular dermal matrix allograft. Clinical records were collected from 16 patients with single gingival recessions who visited a private practice in Periodontics in 2005 and 2006. They were treated through a coronally positioned flap and acellular dermal matrix allograft. The following periodontal parameters were recorded at baseline, 6, 12 and 24 months: Recession Depth, Recession Width, Probing Depth, Clinical Attachment Level, Keratinized Tissue Width, Plaque Index, Gingival Index and Sensitivity. The percentage of root coverage was 91.18 ± 21.26 at 6 months, 90.18 ± 22.04 at 12 months and 90.83 ± 18.41 at 24 months. Complete root coverage was 81% (13 out of 16) at 6 and 12 months. At 24 months, complete root coverage was 75% (9 out of 12). The plaque and gingival indexes did not vary significantly between baseline and measurement times. Probing depth was maintained at healthy levels during the months of follow-up. Sensitivity decreased at 12 months (4 of 16) compared to baseline (14 of 16), and was maintained at 2 years (2 of 12). This retrospective study showed that acellular dermal matrix allograft could be considered a useful alternative for the treatment of single gingival recessions, reducing the discomfort and morbidity associated with the palatal donor site.

scholarly journals Comparison of acellular dermal matrix allograft (ADMA) and a subepithelial connective tissue graft (SCTG) for the treatment of gingival recession

2020 ◽  
Vol 12 (1) ◽  
pp. 11-17
Author(s):  
Niloofar Jenabian ◽  
Mohadese Yazdanpanahbahabadi ◽  
Parya Haghpanah Aski ◽  
Ali Bijani
Keyword(s):  
Connective Tissue ◽  
Test Group ◽  
Acellular Dermal Matrix ◽  
Gingival Recession ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Connective Tissue Graft ◽  
Tissue Graft ◽  
Subepithelial Connective Tissue Graft ◽  
Acellular Dermal

Background. This study aimed to evaluate the effect of acellular dermal matrix allograft (ADMA) for the treatment of gingival recession as a substitute for subepithelial connective tissue graft (SCTG). Methods. In this controlled clinical trial, 18 teeth were selected in nine subjects with bilateral gingival recession. One side was treated with SCTG and a coronally displaced flap as the control group, and the other side was treated with ADMA and a coronally displaced flap as the test group. Probing pocket depth (PPD), clinical attachment level, vertical recession depth, recession width, gingival thickness, keratinized tissue width, and the root coverage percentage were measured before the surgery and at 1-, 3-, and 6-month postoperative intervals. The healing index, pain index, and patient satisfaction were also investigated. The data were analyzed with a general linear model (GLM) repeated measures and paired t-test. Results. All the parameters improved except for PPD; however, a comparison between the groups did not reveal statistically significant differences. Only root coverage percentage and pain index were significantly lower in the test group. The average percentage of root coverage in the control and test groups were 82.01±16.62% and 64.44±9.4%, respectively. Conclusion. Both methods resulted in improvements in the clinical results. However, the use of the ADMA led to less pain and root coverage in comparison with the SCTG method.

Acellular dermal matrix graft with or without enamel matrix derivative for root coverage in smokers: a randomized clinical study

2012 ◽  
Vol 39 (4) ◽  
pp. 393-399 ◽  
Author(s):  
Luciana B. Alves ◽  
Priscila P. Costa ◽  
Sérgio Luís Scombatti de Souza ◽  
Márcio F. de Moraes Grisi ◽  
Daniela B. Palioto ◽  
...  
Keyword(s):  
Clinical Study ◽  
Acellular Dermal Matrix ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Randomized Clinical Study ◽  
Acellular Dermal ◽  
Matrix Derivative
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