Faculty Opinions recommendation of Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice.

Author(s):  
Philippe Saas ◽  
Sylvain Perruche
Author(s):  
Marina Valente Barroso ◽  
Josiane Sabbadini Neves

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Vol 192 (11) ◽  
pp. 5314-5323 ◽  
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Ruslan Hlushchuk ◽  
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Allergy ◽  
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Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a process of evolutionary convergence in multicellular organisms through the application of a congruency test. Furthermore, we discuss why multicellularity is related to the presence of a mechanism initiating the formation of ETs.


2011 ◽  
Vol 127 (2) ◽  
pp. AB205-AB205
Author(s):  
D. Simon ◽  
S. Hoesli ◽  
N. Roth ◽  
S. Staedler ◽  
S. Yousefi ◽  
...  

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