Faculty Opinions recommendation of Antibiotic susceptibility of Propionibacterium acnes isolated from patients with acne in a public hospital in Southwest China: prospective cross-sectional study.

Author(s):  
Gabriella Fabbrocini
BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e022938 ◽  
Author(s):  
Tingting Zhu ◽  
Wenyi Zhu ◽  
Qisa Wang ◽  
Li He ◽  
Wenjuan Wu ◽  
...  

ObjectiveAntibiotics have been routinely used for several decades againstPropionibacterium acnes(P. acnes), but antibiotic resistance ofP. acnesis becoming a global problem. Only one related Chinese study is available. The aim of this study was to assess the antibiotic susceptibility ofP. acnesobtained from patients with acne in Southwest China.DesignThis was a prospective cross-sectional study. Cutaneous samples were obtained from acne lesions on the face of 375 patients. Samples were cultured in anaerobic medium to identify the presence ofP. acnes. Susceptibility tests of isolatedP. acneswere performed for tetracycline, doxycycline, clindamycin, erythromycin, azithromycin and clarithromycin using the Epsilometer test.ResultsP. acneswas isolated from 227 patients; 224 isolates (98.7%) were susceptible to doxycycline and 220 (96.9%) were susceptible to tetracycline, followed by clindamycin and clarithromycin in 101 (44.5%) and 102 (44.93%) isolates, respectively. Susceptibility ofP. acneswas detected for erythromycin in 96 (42.3%) patients, followed by azithromycin in 94 (41.4%). Subjects who received antibiotics (topical and oral) had higher frequencies of antibiotic-resistantP. acnesas well as increased antibiotic minimum inhibitory concentrations compared with patients without antibiotic treatment.ConclusionsP. acneswas highly sensitive to cyclines (doxycycline and tetracycline).P. acnesshowed higher resistance rates to macrolides–lincosamides–streptogramins antibiotics (such as erythromycin, azithromycin, clarithromycin and clindamycin). The irrational use of antibiotics for acne treatment is probably a problem in China and elsewhere. These results suggest that dermatologists should be more prudent in prescribing antibiotics for acne.


2019 ◽  
Vol 47 (9) ◽  
pp. 1107-1111
Author(s):  
Alex S. Jorge ◽  
Barbara S. Horvath ◽  
Claudia Ariati ◽  
Jessica C. Silva ◽  
Lucas B. Lima ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0196217 ◽  
Author(s):  
Agnès Libois ◽  
Marie Hallin ◽  
Tania Crucitti ◽  
Marc Delforge ◽  
Stéphane De Wit

2011 ◽  
Vol 5 (6) ◽  
pp. 1483
Author(s):  
Maria Cláudia Moreira de Alcântara ◽  
Francisca Alexandra Araújo da Silva ◽  
Thereza Maria Magalhães Moreira ◽  
Maria Euridéa de Castro ◽  
Jênifa Cavalcante dos Santos

ABSTRACTObjective: to identify nursing problems of children with hydrocephalus and myelomeningocele in the use of ventricular shunts. Method: cross-sectional study, quantitative, developed in an internment unit for pediatric neurosurgery in a public hospital. The sample consisted of 60 patients admitted from June to December 2006. The study was submitted to the ethics committee of research on Protocol No. 82/2006. Results: the findings showed that the main problems and nursing diagnoses are related to decreased intracranial adaptive capacity related to increased ICP, risk of impaired skin integrity related to immobility and / or frequent exposure to fecal / urinary secretion and urinary incontinence  related neurogenic bladder. Conclusion: ventricular shunts are important methods to improve survival of children with hydrocephalus. But the care provided and the handling of the devices must be well oriented to families by the multiprofessional team, aiming to reduce the long periods of re-internments. Descriptors: nursing; child health; hydrocephalus; myelomeningocele; drainage.RESUMOObjetivo: identificar problemas de enfermagem de crianças com hidrocefalia e mielomeningocele em uso de derivações ventriculares. Método: estudo transversal, quantitativo, desenvolvido em uma unidade de internação em neurocirurgia pediátrica de um hospital público. A amostra constituiu-se de 60 pacientes internados de junho a dezembro de 2006. O estudo foi submetido ao comitê de ética em pesquisa com protocolo n°82/2006. Resultados: os achados evidenciaram que os principais diagnósticos e problemas de enfermagem relacionam-se à capacidade adaptativa intracraniana diminuída relacionada ao aumento da PIC; risco para integridade da pele prejudicada relacionado à imobilidade e/ou exposição frequente à secreção fecal/urinária e incontinência urinária relacionada à bexiga neurogênica. Conclusão: as derivações ventriculares são métodos importantes para aumentar a sobrevida das crianças com hidrocefalia. Porém os cuidados dispensados quanto ao manuseio dos dispositivos devem ser bem orientados pela equipe multiprofissional às famílias, objetivando reduzir os longos períodos de re-internações. Descritores: enfermagem; saúde da criança; hidrocefalia; mielomeningocele; drenagem.RESUMENObjetivo: identificar problemas de enfermería en niños con hidrocefalía y  mielomeningocele que usan derivaciones ventriculares. Método: estudio transversal, cuantitativo, desarrollado en una unidad de internación en neurocirugía pediátrica de un hospital público. La muestra fue compuesta por 60 pacientes internados entre junio y diciembre de 2006. El estudio fue sometido al comité de ética en investigación con el protocolo n°82/2006. Resultados: los resultados demostraron que los principales diagnósticos y problemas de enfermería están relacionados con la capacidad adaptativa intracraneal disminuida asociada al aumento de la PIC; riesgo para la integridad de la piel perjudicada relacionado a la inmovilidad y/o exposición frecuente a secreción fecal/urinaria e incontinencia urinaria asociada a vejiga neurogénica. Conclusión: las derivaciones ventriculares son métodos importantes para aumentar la sobrevida de los niños con hidrocefalía, sin embargo las familias deben ser bien orientadas  por el equipo multiprofesional sobre los cuidados con el manejo de los dispositivos, con el objetivo de reducir los largos periodos de reinternación. Descriptores: enfermería; salud del niño; hidrocefalía; mielomeningocele; drenaje.


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