scholarly journals Bioengineered Zinc Oxide Nanoparticles for Anti-Oxidant Applications

2019 ◽  
Vol 8 (4S2) ◽  
pp. 1003-1006

Zinc oxide nanoparticles find its versatile application in medicine and industry when compared with other metal nanoparticles. The present study focuses on biogenic synthesis of Zinc Oxide nanoparticles (ZnONPs) using lemon juice extract. Lemon juice extracts contains natural alkaloids and flavonoids which acts as reducing agent for the synthesis of nanoparticles. The synthesized zinc oxide nanoparticle is characterized by Scanning Electron Microscopy (SEM) and FTIR. FTIR results showed the presence of functional groups which represents ZnONPs and reducing groups responsible for the reduction. The SEM observation reveals the synthesized ZnONPs are cube shaped. The obtained nanoparticle was further studied for toxicity using zebrafish embryos. Toxicity results suggested that the toxicity is dose dependent. Malformations in the embryos such as yolk sac edema and twisted tail were seen in higher concentrations. The antioxidant activity of the synthesized ZnONPs was carried out using DPPH assay. Results implied that the antioxidant activity was also concentration dependent.

2020 ◽  
Vol 11 (3) ◽  
pp. 4372-4377
Author(s):  
Aparna J ◽  
Rajeshkumar S

The main aim of this study was to employ Maranta arundinacea root extract in the synthesis of Zinc oxide nanoparticles and check the antioxidant activity and cytotoxic effect. The use of nanotechnology in medicine especially for drug delivery is shown to have numerous benefits. Nanoparticles are being used to lessen toxicity and facet results that capsules may additionally impose on the patient. The zinc oxide nanoparticles synthesized using different plant extract used for many biomedical applications such as anticancer activity, antibacterial activity, antioxidant activity, antifungal activity and many more applications used in medicine ( Diagnosis and drug) Plant mediated organic synthesis of nanoparticles has been gaining importance because of its simplicity and eco friendliness. Maranta arundinacea mediated Zinc oxide nanoparticles were initially synthesised and characterised by UV-Visible spectrophotometer and TEM. Further the Maranta arundinacea mediated ZnoNPs were subjected to DPPH assay to determine the antioxidant activity. Maranta arundinacea mediated ZnoNPs were biosynthesised with ease and showed good antioxidant and cytotoxic activity . This study concludes that Maranta arundinacea mediated ZnoNPs nanoparticles have the potential to be used as an effective antioxidant. Hence, it may be employed in large scale production and may be used in many medicinal applications where there is a need for antioxidant.


Author(s):  
C. M. Aathira ◽  
Lakshminarayanan Arivarasu ◽  
S. Rajeshkumar

Aim: To study the anti-inflammatory and antioxidant activity of chromium Picolinate mediated Zinc oxide nanoparticles. Introduction: Chromium is required by the body in a noticeable amount, even though it’s mechanism and required dietary allowance is not known clearly. It is found in supplements. It is expected to enhance insulin production and weight loss. Zinc oxide also has its own beneficial role in various biomedical applications. In the present study the antioxidant and anti-inflammatory potential of the chromium picolinate mediated Zinc oxide nanoparticle is evaluated. Nanoparticles are of great interest nowadays in research and study. The outcomes of using metal nanoparticles were fascinating as color pigments in luster and glass technology. Materials and Methods: DPPH assay for antioxidant activity and Protein denaturation assay was performed for anti-inflammatory activity. Results and Discussion: Chromium Picolinate mediated Zinc oxide nanoparticles showed good anti-inflammatory and antioxidant activity at higher concentration against standard.


2021 ◽  
Vol 11 (2) ◽  
Author(s):  
E. Y. Shaba ◽  
J. O. Jacob ◽  
J. O. Tijani ◽  
M. A. T. Suleiman

AbstractIn this era, nanotechnology is gaining enormous popularity due to its ability to reduce metals, metalloids and metal oxides into their nanosize, which essentially alter their physical, chemical, and optical properties. Zinc oxide nanoparticle is one of the most important semiconductor metal oxides with diverse applications in the field of material science. However, several factors, such as pH of the reaction mixture, calcination temperature, reaction time, stirring speed, nature of capping agents, and concentration of metal precursors, greatly affect the properties of the zinc oxide nanoparticles and their applications. This review focuses on the influence of the synthesis parameters on the morphology, mineralogical phase, textural properties, microstructures, and size of the zinc oxide nanoparticles. In addition, the review also examined the application of zinc oxides as nanoadsorbent for the removal of heavy metals from wastewater.


2017 ◽  
Vol 9 (5) ◽  
pp. 116 ◽  
Author(s):  
Khoushika Raajshree R. ◽  
Brindha Durairaj

Objective: The present study was designed to evaluate the antioxidant and antityrosinase properties of zinc oxide nanoparticles (ZnO-NPs) synthesized from brown seaweed Turbinaria conoides.Methods: Zinc Oxide Nanoparticles were synthesized from the hydroethanolic extract of Turbinaria conoides. Ultraviolet-Visible Spectrophotometric analysis was performed to confirm the formation of ZnO-NPs. Size, morphology and elemental composition of ZnO-NPs were analysed using SEM-EDAX. The antioxidant activity of the synthesized zinc oxide nanoparticles was investigated by total antioxidant capacity (phosphomolybdenum method), reducing power assay and ferric reducing antioxidant power assay (FRAP). Anti tyrosinase activity was assessed to validate the skin whitening ability of the ZnO-NPs. Results: The antioxidant activity of ZnO-NPs synthesized from hydroethanolic extract of Turbinaria conoides was maximum when compared with that of the hydroethanolic algal extract. The antityrosinase activity of ZnO-NPs was found to be maximum with 75% tyrosinase inhibition when compared to hydroethanolic algal extract which had 56% inhibition at 250μg/ml concentration.Conclusion: Overall our study provides a firm evidence to support that antityrosinase and antioxidant activities are exhibited by ZnO-NPs synthesized from hydroethanolic extract of Turbinaria conoides and it might be used as an antioxidant and as a source of skin whitening agent in cosmetics.


2020 ◽  
Vol 11 (3) ◽  
pp. 4690-4694
Author(s):  
Tahoora Taskeen. L ◽  
Hannah R ◽  
Rajeshkumar S

To determine the free radical scavenging activity of fruit formulation mediated zinc oxide nanoparticle. Zinc oxide nanoparticles are widely known for their antimicrobial agent, anti-diabetic, anti-inflammatory, wound healing, antioxidant and optic properties. Oxidative degradation of lipids, proteins, food and cosmetics involves a radical-chain reaction with release of free radicals. These free radicals are extremely reactive and can even attack relatively stable molecules like the DNA bases. With a recent rise in diseases associated with increased oxidative stress, a good antioxidant seems to be the need of the hour. Synthesis of zinc oxide nanoparticles using Punica granatum and Elettaria cardamomum extract. Characterisation of the nanoparticles using UV–Visible spectroscopy and Scanning electron microscope. It is followed by the DPPH radical scavenging assay to determine the antioxidant activity. With an increase in the concentration of zinc oxide nanoparticles, there was an increase in the percentage of inhibition. When compared to the standard, the zinc oxide nanoparticles showed increased antioxidant activity even in small concentrations. Punica granatum and Elettaria cardamomum mediated Zinc oxide nanoparticles showed considerable antioxidant property even in small quantity when compared with standard vitamin C. Further studies need to be carried out to check for its potency as a prophylactic agent.


2016 ◽  
Vol 70 (11) ◽  
Author(s):  
Kateřina Hrdá ◽  
Jakub Opršal ◽  
Petr Knotek ◽  
Miloslav Pouzar ◽  
Milan Vlček

AbstractToxicity of zinc oxide nanoparticle (ZnO-NPs) powder and water soluble salt of Zn (ZnCl


2020 ◽  
Vol 27 (1) ◽  
pp. 102-110
Author(s):  
Maryam Kokabi ◽  
Samad Nejad Ebrahimi

Background: Green synthesized nanoparticles (NPs) from agricultural wastes is an area of great interest due to it is eco-friendly and profitable. Zinc oxide is an inorganic UV-filter commonly used as UV-blocker in a different industry. Methods: Zinc oxide nanoparticles (ZnO NPs) were successfully biosynthesized using Zn(NO3)2 as a substrate by polyphenol enriched fraction (PEF) of pomegranate peel. The biological activity of ZnO NPs was evaluated using MBC and MIC tests for antibacterial and DPPH assay for antioxidant potential. Sunscreen potential of NPs was determined after applying them in water-in-oil emulsions. Results: UV-Vis and FT-IR spectroscopy techniques confirmed the formation of ZnO NPs. FE-SEM characterized the morphology and purity of the biosynthesized NPs with EDAX and XRD data. The average crystalline size of ZnO NPs was found to be 22 nm. FT-IR spectroscopy revealed the role of phenolic compounds in the formation and stability of ZnO NPs. The antibacterial activity of PEF and its biosynthesized ZnO was evaluated against Staphylococcus aureus and Escherichia coli. The prepared NPs showed a higher antibacterial effect than the commercial ZnO NPs. Interestingly, the antioxidant activity was also detected for obtained NPs. The PEF powder also exhibited higher antibacterial and antioxidant activity than the standards. Furthermore, the in vitro sun protection factors were estimated after applying NPs in water-in-oil emulsions. Conclusion: This study highlighted the possibility of using PEF of pomegranate peel for the biosynthesis of ZnO NPs as well as applying its NPs in sunscreens to achieve a safe alternative to harmful chemical UV-filters commonly used in cosmetics.


Author(s):  
N. Tensingh Baliah ◽  
Muthulakshmi P. ◽  
S. Lega Priyatharsini

Green synthesis of nanoparticles has attracted considerable attention in recent years. In this regard, plants extracts and natural resources such as microorganisms and enzymes have been found to be good alternative reagents in nanoparticles synthesis. Utilizing green substances has several advantages including low energy consumption and moderate operation conditions without using any toxic chemicals. An attempt was made to synthesis and characterizes the silver doped zinc oxide nanoparticles (Ag doped ZnO NPs) by using onion extract. The synthesized Ag doped ZnO NPs were characterized by Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy Analysis (EDAX), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD) and Zeta potential analyses. These characterizations revealed that doped nanoparticles are differed in their structural properties. The onion extract was used as reducing agent as well as stabilizer. The phytochemicals found in the onion extract were responsible for the formation of Ag doped ZnO NPs.


Author(s):  
Prashast Kumar Tripathi Satish Chandra Sati

Abstract-In this research paper we have reported the single pot synthesis of zinc oxide nanoparticles (ZnONPs) for the first time by utilisation of leaves extract of Himalayan medicinal plant Artemisia roxburghiana. The principle of green chemistry was utilised at maximum possible level to make the synthesis not only environmentally compatible but also cost effective. The obtained nanoparticles are of good shape and size as confirmed by the instrumental techniques such as Powder XRD, HR-TEM, HR-SEM and FT-IR. The average size of the synthesized nanoparticles was between 26 to 35 nm. These nanoparticles then screened for the anti - microbial assay in which it has shown positive activity against E. coli, A. Tereus and C. falcatum. The second application of the synthesized nanoparticles is estimation of anti - oxidant activity against the DPPH. The IC value of the nanoparticles is formed to be 50 53 in EtoH while that of the standard, ascorbic acid was 26 in the same solvent. Keywords:Art emisia roxburghiana, Asteraceae, ZnONPs, Antimicrobial activity and Antioxidant activity


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