PHYTOCHEMICAL PROFILING OF OXALIS CORNICULATA LEAF EXTRACT

2021 ◽  
pp. 20-21
Author(s):  
Remya A. S. ◽  
Annie Abraham
Keyword(s):  
Plant Extract ◽  
Leaf Extract ◽  
Therapeutic Agents ◽  
Volatile Components ◽  
Ftir Analysis ◽  
Chromatographic Separations ◽  
Characteristic Functional ◽  
Essential Step ◽  
Valuable Method ◽  
Phytochemical Compounds

Elucidation of the phytochemical composition of plant extract is an essential step in developing novel therapeutic agents from medicinal plants. Mass spectrometry, coupled with chromatographic separations (GC/MS), is increasingly applied to analyze plant extracts as this technique has proved to be a valuable method for the analysis of nonpolar volatile components and alkaloids. Fourier transform infrared (FTIR) is being used for the identication of characteristic functional groups present in the plant extract. The absorption spectrum provides information about the structure of the molecules present in the phytoextract. FTIR analysis revealed the presence of phenols, alkane, alkene, carboxylic acid, aromatic compounds, alcohol, and bromo alkane compounds in methanolic leaf extract of Oxalis corniculata and GC/MS analysis provide different peaks determining the presence of twenty three phytochemical compounds.

scholarly journals ETHNOBOTANICAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL PROPERTIES OF NEPENTHES SPECIES: A REVIEW

2017 ◽  
Vol 10 (11) ◽  
pp. 16 ◽  
Author(s):  
Shuaibu Babaji Sanusi ◽  
Mohd Fadzelly Abu Bakar ◽  
Maryati Mohamed ◽  
Siti Fatimah Sabran ◽  
Muhammad Murtala Mainasara
Keyword(s):  
Folk Medicine ◽  
Therapeutic Agents ◽  
Bioactive Components ◽  
Pharmacological Activities ◽  
Crude Extracts ◽  
Gastrointestinal Discomfort ◽  
Wide Range ◽  
Long Time ◽  
Phytochemical Compounds ◽  
Ethnobotanical Uses

The genus Nepenthes (Nepenthaceae) has been utilized in folk medicine for a long time in India and Southeast Asia countries. They are used in the treatment of leprosy, cholera, night blindness, gastrointestinal discomfort, dysentery, stomachache, and bed-wetting among others. This review highlights the ethnobotanical uses, phytochemicals, and pharmacological activities of both crude extracts and pure bioactive compounds of Nepenthes spp. The phytochemical compounds isolated from Nepenthes species include flavonoids, terpenoids, tannins, alkaloids, and steroids among other phytochemicals. A wide range of pharmacological activities was exhibited by the crude extracts and pure bioactive components such as antibacterial, antifungal, antimalarial antioxidant, antidiabetic, antiosteoporotic, anti-inflammatory, cytotoxicity, and hypolipidemic activities. This review revealed that many active compounds are present in Nepenthes spp. However, many pharmacological screenings such as anticancer, antiviral, wound healing, antihelminthic, antidiarrheal properties, among others have not been carried out yet. Therefore, more biological investigations and phytochemical screenings are required to fully explore the genus Nepenthes which may lead to development of new therapeutic agents.  

scholarly journals Studies on the Phytochemical Compounds in the Ethanolic Leaf Extract (ELE), Ethanolic Bark Extract (EBE) and Ethanolic Root Extract (ERE) of Bridelia ferruginea Benth (Euphorbiaceae)

2019 ◽  
pp. 1-8 ◽  
Author(s):  
Abdullahi Attah Alfa ◽  
Orukotan Abimbola Ayodeji ◽  
Goji Anthony Donatus Teru ◽  
Kokori Bajeh Tijani
Keyword(s):  
Pathogenic Bacteria ◽  
Leaf Extract ◽  
Bioactive Compound ◽  
Fats And Oils ◽  
Bark Extract ◽  
Root Extract ◽  
Suction Pump ◽  
Plant Parts ◽  
Bridelia Ferruginea ◽  
Phytochemical Compounds

The phytochemical compounds of Bridelia ferruginea plant parts was carried out using qualitative method to determine the bioactive compounds present in the plant leave, stem bark and root extracts. The samples was weighed, of which 100 g each of the powder were extracted in solvents (ethanol) 1000 ml macerated and stand for 72 hours. The solvents contained in the maceration bottle was decanted and filtered using a filter paper, the filtration was aided using a suction pump. The filtrate was concentrated using a rotary evaporator and then transferred into thermostatic water cabinet (Temperature was set at 45oC), allowed to dry completely. The plant parts extracts were separately kept in a screw capped bottle for further research. The bioactive compound in the plant parts were detected. The result revealed that Carbohydrates, Saponins, Flavonoids, Tannins, Cardiac Glycosides, fats and oils were present. Alkaloid present in Dragendoff’s test in all plant parts extract but absent in Mayer’s test in only leaf extract. Terpenoids/Steroids present in Liebermann-Burchard’s test in all plant parts extract but absent in Salkowski’s test in only leaf extract. Anthraquinones were absent in all plant parts extracts using Bontrager’s test. Therefore, the presence of these phyto-pharmacological compounds is an indicative that the plant is medicinal and it can be used for the treatment of bacterial and other microbial infections. Further study can be done to separate the individual metabolites to test their antimicrobial activity against some pathogenic bacteria like bacterial meningitis, tuberculosis and syphilis to determine their potency.

scholarly journals تثبيط التغيرات الخلوية الوراثية المستحثة بعقار MMC في الفأر الأبيض باستخدام مستخلصي نبات القريص نوع Urtica pilulifera

2007 ◽  
Vol 1 (1) ◽  
pp. 37-51
Author(s):  
Ismail Kadhum Shubber ◽  
Laith Abdel Hassan ◽  
Saadi Hamad Hilal
Keyword(s):  
Bone Marrow ◽  
Cell Division ◽  
Plant Extract ◽  
Chromosomal Aberrations ◽  
Leaf Extract ◽  
Marrow Cell ◽  
Ethanolic Extract ◽  
Genotoxic Effects ◽  
Control Drug ◽  
Cytogenetic Effects

The aim of this study was to investigate the potency of aquatic & alcoholic extracts of the leaves of Urtica pilulifera plant against mutagenecity of Mitomycine C (MMC) drug in mice.The genotoxic effects of three different concentrations 0.01, 0.1 & 0.5 mg/kg from aqueous or ethanolic extract were tested in mice. 0.01 mg/kg bw from either types of extracts were selected as non-genotoxic in comparison to control. Drug-plant extract interaction was tested using mitotic index & Chromosomal aberrations as bioindicators for detection of the potency of the plant extract in reduction of MMC-induction of cytogenetic effects. Two types of treatments were followed, either plant extracts were given before (2, 4, 6) days, or after (2, 4, 6) days, of treatment with MMC. The results revealed that 0.2 mg/kg of MMC significantly inhibited bone marrow cell division and increased the spontaneous levels of chromosomal aberration up to 20 times. Treatment of mice with aqueous or alcoholoic leaf-extract reduced significantly (p < 0.01) the genotoxic effects of MMC. This reduction was more pronounced in animals which were given the extract after treatment with MMC comparing to its treatment before the MMC exposure. These results indicated that Utrtica pilulifera leaves extract behave as bio-anti mutagen first degree and acting indirectly in the 2nd degree.

scholarly journals Pharmacognostical, Phytochemical, Antioxidant and Antimicrobial Activity of Costus woodsonii

2019 ◽  
pp. 53-59
Author(s):  
Mukesh S Sikarwar ◽  
Chew Khai Szeek ◽  
Neeraj Paliwal
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Plant Extract ◽  
Total Phenolic Content ◽  
Leaf Extract ◽  
Phenolic Content ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Concentration Test ◽  
Antioxidant And Antimicrobial Activity

Background: Herbal medicine mostly contains wide range of chemical compounds responsible for medicinal therapeutic use. Costus woodsonii is commonly called as Red Button Ginger and synonyms of the botanical name are Costus spiralis, Alpinia spiralis and Costus pisonis. In Malay, it is known as Setawar Halia Merah. In Chinese, it is known as Hong Bi Qiao Jiang. Objective: This research was conducted to study the pharmacognostical, phytochemical, antioxidant and antimicrobial activity of C. woodsonii leaf extracts. Method: Macroscopy, microscopy, phytochemical analysis, thin layer chromatography, antioxidant activity and antimicrobial activity of C. woodsonii leaf were carried out. Total flavonoids were estimated in the leaf extract. The total phenolic content of C. woodsonii leaf was determined using Folin-Ciocalteu reagent. The antioxidant activity of leaf extract of C. woodsonii was determined by performing DPPH radical scavenging. The microbial activity was determined by Well diffusion test, MIC (Minimum Inhibitory Concentration) test and MBC (Minimum Bactericidal Concentration) test. Result and Discussion: C. woodsonii belongs to costaceae with elliptical green leaves. Till now are no extensive studies on C. woodsonii. Preliminary phytochemical analysis revealed the presence of flavonoid, steroid, fat, phenol, tannin and mucilage in leaf extract. Physicochemical studies further revealed the ash value of leaf as 8.7%. Among the three extractions, alcohol extractive values showed the highest as 13%. Loss on drying at 105 degree Celsius in leaf was found to be 12.67%. The plant extract showed total phenolic content of 7.941 mg GAE/g at concentration of 5µg/ml. As for flavonoids content, plant extract showed 21.7 mg RE/g at concentration of 200µg/ml and 43.4 mg RE/g at concentration of 400µg/ml. For antioxidant activity, the plant extract showed weak antioxidant activity in DPPH scavenging activity assay. For antimicrobial test, the leaf extract of C. woodsonii showed weak antimicrobial activity. Conclusion: From this study, it can conclude that C. woodsonii leaf extract possess weak antioxidant activity and weak antimicrobial activity which need to be further validated by using more antioxidant assays and antimicrobial tests.

Application Of Vegetable Insecticide With Swamp Plant On Soybeanbork Pest Inland Of Tidal Swamp

2020 ◽  
Vol 9 (2) ◽  
pp. 15-21
Author(s):  
Ni'matuljannah Akhsan
Keyword(s):  
Plant Extract ◽  
Leaf Extract ◽  
Block Design ◽  
Botanical Insecticide ◽  
Insecticide Treatment ◽  
Randomized Block Design ◽  
Tidal Swamp ◽  
Pod Borer ◽  
Tidal Swamps ◽  
The Village

ABSTRACT The aim of this research is to control environmentally friendly soybean pod borer by utilizing plants in swamps as a vegetable insecticide, namely Kepayang (Pangiumedule). The study was conducted on tidal land in the Village of Kiri Dalam, Barambai District, Barito Kuala Regency, South Kalimantan Province. The study was designed in a randomized block design with 5 replications. The treatment is; 1. Kepayang leaf extract, 2. Without control, 3.Neem plant extract, 4. Chloriliprol insecticide. The results showed that the Kepayang leaf extract can be used as a botanical insecticide controlling soybean pod borer because it can suppress soybean pod attack by up to 62% and is no different from the Chloriliprol insecticide treatment by 64%. Keywords: Applications, Swamp Plants, Boring Pods Borers, Tidal Swamps

scholarly journals GC–MS analysis of phytoconstituents from Amomum nilgiricum and molecular docking interactions of bioactive serverogenin acetate with target proteins

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Narasimhamurthy Konappa ◽  
Arakere C. Udayashankar ◽  
Soumya Krishnamurthy ◽  
Chamanalli Kyathegowda Pradeep ◽  
Srinivas Chowdappa ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Ethyl Acetate ◽  
Plant Species ◽  
In Silico ◽  
Leaf Extract ◽  
Target Proteins ◽  
Methanol Extracts ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
In Silico Molecular Docking

Abstract Amomum nilgiricum is one of the plant species reported from Western Ghats of India, belonging to the family Zingiberaceae, with ethno-botanical values, and is well-known for their ethno medicinal applications. In the present investigation, ethyl acetate and methanol extracts of A. nilgiricum were analyzed by Fourier transform infrared spectrometer (FTIR) and gas chromatography-mass spectrometry (GC–MS) to identify the important functional groups and phytochemical constituents. The FTIR spectra revealed the occurrence of functional characteristic peaks of aromatic amines, carboxylic acids, ketones, phenols and alkyl halides group from leaf and rhizome extracts. The GC–MS analysis of ethyl acetate and methanol extracts from leaves, and methanol extract from rhizomes of A. nilgiricum detected the presence of 25 phytochemical compounds. Further, the leaf and rhizome extracts of A. nilgiricum showed remarkable antibacterial and antifungal activities at 100 mg/mL. The results of DPPH and ferric reducing antioxidant power assay recorded maximum antioxidant activity in A. nilgiricum methanolic leaf extract. While, ethyl acetate leaf extract exhibited maximum α-amylase inhibition activity, followed by methanolic leaf extract exhibiting aldose reductase inhibition. Subsequently, these 25 identified compounds were analyzed for their bioactivity through in silico molecular docking studies. Results revealed that among the phytochemical compounds identified, serverogenin acetate might have maximum antibacterial, antifungal, antiviral, antioxidant and antidiabetic properties followed by 2,4-dimethyl-1,3-dioxane and (1,3-13C2)propanedioic acid. To our best knowledge, this is the first description on the phytochemical constituents of the leaves and rhizomes of A. nilgiricum, which show pharmacological significance, as there has been no literature available yet on GC–MS and phytochemical studies of this plant species. The in silico molecular docking of serverogenin acetate was also performed to confirm its broad spectrum activities based on the binding interactions with the antibacterial, antifungal, antiviral, antioxidant and antidiabetic target proteins. The results of the present study will create a way for the invention of herbal medicines for several ailments by using A. nilgiricum plants, which may lead to the development of novel drugs.

Plant-extract-assisted green synthesis and its larvicidal activities of silver nanoparticles using leaf extract of Citrus medica, Tagetes lemmonii, and Tarenna asiatica

2020 ◽  
pp. 129265
Author(s):  
K. Chandhirasekar ◽  
A. Thendralmanikandan ◽  
Pazhanivel Thangavelu ◽  
Ba-Son Nguyen ◽  
Trong-Anh Nguyen ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Plant Extract ◽  
Leaf Extract ◽  
Citrus Medica ◽  
Larvicidal Activities

scholarly journals Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi) sebagai Antioksidan dan Antiinflamasi

2019 ◽  
Vol 8 (3) ◽  
pp. 86
Author(s):  
Hasim Hasim ◽  
Yupi Yulianita Arifin ◽  
Dimas Andrianto ◽  
Didah Nur Faridah
Keyword(s):  
Antioxidant Activity ◽  
Leaf Extract ◽  
Ethanol Extract ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Phytochemical Compounds ◽  
Anti Inflammatory ◽  
Ethanol Extracts ◽  
Phenolic And Flavonoid

Belimbing wuluh merupakan tanaman jenis buah dan obat tradisional. Tanaman belimbing wuluh sudah sering dimanfaatkan masyarakat salah satunya untuk mengobati penyakit seperti batuk dan radang rektum. Tujuan penelitian ini adalah menguji senyawa fitokimia, menganalisis kandungan total fenolik dan flavonoid, serta aktivitas antioksidan dan antiinflamasi secara in vitro pada ekstrak etanol daun belimbing wuluh. Metode yang dilakukan pada penelitian ini adalah ekstraksi daun belimbing wuluh, skrining fitokimia, perhitungan total fenol dan flavonoid, uji aktivitas antioksidan, dan uji aktivitas antiinflamasi. Senyawa fitokimia yang terkandung pada ekstrak etanol daun belimbing wuluh adalah saponin, tanin, steroid, flavonoid, dan alkaloid. Kandungan total fenolik dan flavonoid ekstrak etanol daun belimbing wuluh secara berturut-turut sebesar 39,03 dan 97,28 µg QE/mg. Ekstrak etanol daun belimbing wuluh memiliki aktivitas antioksidan yang tergolong sangat kuat, sementara aktivitas antiinflamasinya terutama ditunjukkan pada konsentrasi ekstrak 200 µg/ ml, memiliki nilai persen inhibisi hemolisis yang paling tinggi. Kesimpulannya, ekstrak etanol daun belimbing wuluh dapat menjadi salah satu sumber antioksidan dan antiinflamasi alami.Ethanol Extracts of Averrhoa Bilimbi Leaf Demonstrated Antioxidative and Anti-inflammatory ActivityAbstractAverrhoa bilimbi, a fruit-bearing plant, has been traditionally used for medicinal purposes such as treatment of cough and rectal inflammation. In this current work, ethanol extract of Averrhoa bilimbi leaf was analyzed, with regard to phytochemical composition, i.e. total phenolic, and flavonoid, antioxidant activity, and in vitro antiinflammation activity. Extraction of carambola leaves, phytochemical screening, total phenolic and flavonoid contens, assay of antioxidant activity, and assay of anti-inflammatory activity were done in this research. As a result, the leaf extract positively contained some phytochemical compounds, i.e. saponin, tannin, steroid, flavonoid, and alkaloid. Furthermore, total phenolic and flavonoid of the leaf extract was found at 39.03 and 97.28 µg QE/mg extract, respectively. Additionally, antioxidant activity of the leaf extract was classified as very strong, while its anti-inflammatory feature at extract concentration of 200 µg/ml exhibited the highest inhibition of hemolysis. In summary, the ability of Averrhoa bilimbi leaf ethanol extracts to act as antioxidative and anti-inflammatory agents was determined and this may open the use for natural antioxidant and anti-inflammatory agents.

scholarly journals Preclinical evaluation of antidiabetic activity of poly herbal plant extract in streptozotocin induced diabetic rats

2016 ◽  
Vol 5 (2) ◽  
pp. 45-49
Author(s):  
P.P. Gupta ◽  
◽  
J. Haider ◽  
R.P. Yadav ◽  
U. Pal ◽  
...  
Keyword(s):  
Body Weight ◽  
Plant Extract ◽  
Leaf Extract ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Antidiabetic Activity ◽  
Sprague Dawley ◽  
Pancreatic Cell ◽  
Partial Restoration ◽  
Herbal Plant

Objective: To study and compare the effect of Poly herbal plant extract (PHPE) with Glibenclamide (GL) on various parameters in Streptozotocin (STZ) induced diabetic rats. Methods: Diabetes was induced by combining High Fat-diet and injecting low dose Streptozotocin (35 mg/kg body wt.) to Sprague-dawley rats. Diabetic rats were treated with chloroform leaf extract of Azadirachta indica, aqueous leaf extract of Bougainvillea spectabilis and ethanolic seed extract of Trigonella foenum graecum combined in ratio of 1:2:3 respectively at dose of 600 mg/kg body weight by oral gavaging for 28 days. The results were compared with standard anti diabetic drug Glibenclamide given in dose of 500 µg/kg body weight. Results: Increase in body weight of both PHPE and GL treated diabetic rats was found to be statistically significant (p<0.05) compared to diabetic control rats. Decline in FBG levels of both PHPE and GL treated diabetic rats were found to be highly significant statistically (p<0.001) when compared to diabetic control rats at the end of study. Total Cholesterol (TC) and Triglycerides level in diabetic rats treated with PHPE were found to be highly statistically significant (p<0.001) compared to diabetic control rats. Pancreas of PHPE treated diabetic rats revealed partial restoration in size and number of islet of langerhans. Reduction in widening between acinar and islet cells noted. Glibenclamide treated diabetic rats showed much more improvement in pancreatic cell architecture by returning to its normal structure and size. Conclusion: In present study PHPE has shown to decrease elevated FBG level and improve in body weight at the end of study in diabetic rats which can be suggested due to modification in carbohydrate metabolic pathways, stimulation of insulin production by the pancreas, increased peripheral utilization of glucose in the cells and regeneration of β-cells of the pancreas.

scholarly journals Phytochemical Analysis and Anti-microbial Studies of Leaf Extract of Terminalia arjuna using Spectroscopic Methods

2020 ◽  
Vol 13 (3) ◽  
pp. 322-332
Author(s):  
B. Anita
Keyword(s):  
Leaf Extract ◽  
Therapeutic Agent ◽  
Ethanolic Extract ◽  
Therapeutic Agents ◽  
Vital Role ◽  
Terminalia Arjuna ◽  
Phytochemical Analysis ◽  
Spectroscopic Methods ◽  
Uv Visible ◽  
Anti Fungal

From time immemorial plants have been used as potent therapeutic agents to treat various ailments in the Siddha and Ayurveda streams of medicine. Plants are rich sources of flavonoids, alkaloids, terpenoids and other related polyphenols. One such important plant used for treating heart ailments is Terminalia arjuna. The bark of this plant plays a vital role as cardiac tonic. It also possesses antimicrobial, cytotoxic and antidiabetic properties. The phytochemical activity of the secondary metabolites present in the bark of T.arjuna has been reported widely. But, the medical uses of leaf extract of the plant have seldom been reported. In this work, the ethanolic extract of leaf of T. arjuna has been analysed for the presence of different phytochemicals using FTIR, UV-Visible and GC-MS spectroscopic methods. The various functional groups present in the leaf extract have been identified initially using FTIR and UV-Vis spectra of leaf extract. Next, GC-MS studies revealed the complete structure of the twelve major phytoconstituents that were present in the leaf extract. In the next stage of the study, the therapeutic effect of the extract as potent anti-bacterial and antifungal agent has been studied. The presence of a flavonoid and ester groups in the leaf extract as revealed by the GC-MS analysis and the potential anti-fungal and anti-baterial activity of the extract shows that leaf extract of Terminalia arjuna has a great potential to be used as a therapeutic agent.

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