scholarly journals Total Cholesterol, Triglyseryda, and Coronary Hearth Disease Incidence in Hearth Polyclinic of dr. M. Yunus Hospital Bengkulu

2020 ◽  
Vol 25 (2) ◽  
pp. 1-9
Author(s):  
Nurul Khairani ◽  
Awal Isgiyanto ◽  
Lilis Sumarni

The impact of coronary heart disease (CHD) can cause heart failure and even a deadly heart attack. This study aimed to study the relationship of total cholesterol and triglyceride levels with CHD in patients visiting the Cardiac Polyclinic of        Dr. M. Yunus Bengkulu. This type of research used Analytical Survey with Case Control design. The population in this study was all patients of the Cardiac Polyclinic of RSUD dr. M. Yunus Bengkulu. Case samples in this study were 84 patients with CHD and 84 controls were taken using a Systematic Random Sampling technique. The data in this study used secondary data and data analysis techniques using univariate, bivariate, and multivariate analysis. Data analysis in this study used Chi-Square test (c2). To determine the closeness of the relationship, the Contingency Coefficient (C) test was used. To find out the risk factors used the Odds Ratio (OR) test. The results obtained from 168 people there were 84 people (50.0%) who had CHD, 87 people (51.8%) had total cholesterol levels ≥ 200 mg / dL and 100 people (59.5%) who had triglyceride levels ≥ 150 mg / dL. There was a correlation between total cholesterol levels and triglyceride levels with CHD in patients who visited the Cardiac Polyclinic of  dr. M. Yunus Bengkulu with a moderate relationship category. It is expected that health workers can increase information regarding the prevention and control of total cholesterol levels and triglyceride levels in CHD patients, and recommend to maintain a healthy lifestyle and exercise in order to improve the quality of life of patients with CHD.Keywords: coronary heart disease, total cholesterol levels, triglyceride levels,

2018 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Laila Kamila ◽  
Maulidiyah Salim

Abstract: Coronary heart is a disease that offense to blood vessels and heart attack due to constriction of blood vessels. A high level of cholesterol in blood or exceeds the normal limit can form sediment in wall of blodd vessels which cause blood vessels constriction or blockage. This research object to determine whether there is a correlation between cholesterol level total and hypertension with coronary heart disease in patients who hospitalized in Regional Public Hospital of dr. Soedarso Pontianak. This study was used cross sectional design, purposive sampling technique, it gained 50 people as samples. The measurement of blood pressure was done in heart poly and cholesterol total level in clinic laboratory of Regional Public Hospital of dr. Soedarso by using enzymatic CHOD-PAP method. It can be obtained that 10 people had hypertension and 40 people did not.the average of total cholesterol was 224 mg/dl. Maximum value of total cholesterol was 224 mg/dl and 152 mg/dl as minimum value. Data has been analyzed by using statistical test, Chi-Square, to determine the correlation of total cholesterol wit coronary heart disease, obtained p value=0,024 (less than α=0,05). Correlation of hypertension and coronary heart disease gained p value=0,923 (more than α=0,05), it can be concluded that total cholesterol correlated with coronary heart disease, and there was not a correlation between hypertension and coronary heart disease.Abstrak: Jantung koroner adalah penyakit yang  menyerang pembuluh darah dan serangan jantung, karena penyempitan pada pembuluh darah. Kadar kolesterol yang tinggi dalam darah melebihi normal dapat membentuk endapan pada dinding pembuluh darah sehingga menyebabkan penyempitan dan tersumbatnya pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dan hipertensi dengan penyakit jantung koroner pada pasien di RSUD dr. Soedarso Pontianak. Disain penelitian  ini menggunakan cross sectional, teknik pengambilan sampel yaitu purposive sampling, didapat jumlah sampel 50 orang. Pengukuran Tensi Darah dilakukan di poli Jantung dan pemeriksaan kadar kolesterol total di laboratorium klinik RSUD dr. Soedarso Pontianak dengan metode enzimatik CHOD-PAP. Hasil penelitian didapatkan 10 orang mengalami hipertensi dan 40 orang non hipertensi. Rata-rata kadar kolesterol total 224 mg/ dl. Nilai maksimum kadar kolesterol total yaitu 224 mg/dl dan nilai minimum yaitu 152 mg/dl. Analisa data dengan uji statistik Chi-square untuk mengetahui hubungan kolesterol total dengan penyakit jantung koroner didapatkan nilai p = 0,024 (lebih kecil dari  α 0,05). Uji hubungan hipertensi dengan penyakit jantung koroner didapat nilai p = 0,923 (lebih besar dari α 0,05), dapat disimpulkan terdapat hubungan kadar kolesterol total dengan penyakit jantung koroner dan tidak ada hubungan hipertensi dengan penyakit jantung koroner.


2007 ◽  
Vol 194 (2) ◽  
pp. 415-420 ◽  
Author(s):  
Renzhe Cui ◽  
Hiroyasu Iso ◽  
Hideaki Toyoshima ◽  
Chigusa Date ◽  
Akio Yamamoto ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Haishan Wu ◽  
Lu Deng ◽  
Lipin Zhao ◽  
Jingping Zhao ◽  
Lehua Li ◽  
...  

Schizophrenia is one of the most common global mental diseases, with prevalence of 1%. Patients with schizophrenia are predisposed to diabetes, coronary heart disease, hypertension, and osteoporosis, than the normal. In comparison with the metabolic syndrome, for instance, there are little reports about osteoporosis which occurs secondary to antipsychotic-induced hyperprolactinaemia. There are extensive recent works of literature indicating that osteoporosis is associated with schizophrenia particularly in patients under psychotropic medication therapy. As osteoporotic fractures cause significantly increased morbidity and mortality, it is quite necessary to raise the awareness and understanding of the impact of antipsychotic-induced hyperprolactinaemia on physical health in schizophrenia. In this paper, we will review the relationship between schizophrenia, antipsychotic medication, hyperprolactinaemia, and osteoporosis.


2002 ◽  
Vol 30 (4) ◽  
pp. 608-620 ◽  
Author(s):  
Wendy E. Parmet

The relationship between law and a population’s health is complex and poorly understood. To the extent that scholarship exists on the subject, it has usually focused on epidemics that are concentrated in relatively vulnerable, marginalized communities. Often, individual behaviors are assumed to play a major role in the epidemiology of these diseases. Perhaps, as a result, these illnesses become stigmatized and the object of coercive laws, which in turn become the subject of litigation, legal debate, and ultimately scholarly analysis. Thus, to the extent that U.S. legal scholars have thought about public health in the last 30 years (and they seldom have), they have generally done so in the context of tuberculosis (TB), intravenous drug abuse, and a handful of similar conditions. Likewise, Jonathan Mann’s own appreciation of the importance of human rights to public health emerged in the wake of his work with HIV, which is perhaps the prototypical stigmatized disease.


2017 ◽  
Vol 95 (2) ◽  
pp. 127-131
Author(s):  
Aleksandr V. Dontsov

The study is aimed at elucidating the relationship between the blood b-endorphin level in patients with coronary heart disease (CHD) with metabolic syndrome (MS) and cardiovascular risk factors and evaluating the possibility to correct them by dalargin therapy. The study included 123 patients (61 men and 62 women) at the mean age 57.6±5,2 years randomized into 2 groups. The patients of group 1 (n=63) were given the standard treatment, those of group 2 (n=60) additionally received 2 mg/day of dalargin for 10 days (3 courses during 3 months). The group of comparison (n=84) contained 84 CHD patients without MS. Biochemical and immunological characteristics were measured by immunoenzyme and immunochemiluminescent assays before and 3 months after treatment. The study revealed inverse correlation between b-endorphin levels and those of leptin, insulin, cortisol, TNF-a, IL-6, oxidized LDLP, triglycerides (TG), and HDLP cholesterol. Standard therapy resulted in a 6.5% reduction ofinsulin level, 9,4% , 6,1%, and 17,4% reduction of TNF-a , IL-6, TG levels respectively; it increased the HDLP cholesterol level by 10,3% (p<0,05 for all values) but did not change other parameters of interest. Dalargin therapy caused a 32,6% and 17,4%, rise in the b-endorphin and HDLP cholesterol levels but decreased leptin, insulin, cortisol, TNF-a, IL-6, LDLP, and tG levels by 36,1%, 22,4%, 23,9%, 55%, 56,3%, 14% and 27,2% respectively (p<0,001). It is concluded that the decrease of the blood b-endorphin level in the patients with coronary heart disease and metabolic syndrome is associated with enhanced blood atherogenicity, hyperinsulinemia, hypercortisolemia, activation of pro-inflammatory cytokines and lipid peroxidation. Supplementation of conventional therapy with dalargin results in the increased b-endorphin level, enhanced anti-atherogenic effect, reduced activity ofpro-inflammatory cytokines and lipid peroxidation, reduction of leptin, insulin and cortisol levels.


2018 ◽  
Vol 25 (1) ◽  
pp. 65-74
Author(s):  
Devi Listiana ◽  
Awal Isgiyanto ◽  
Mezi Ade Saputra

The number of stroke patients in Indonesia from year to year continues to increase. Stroke in Indonesia is the number three killer after infectious disease and coronary jatung. The purpose of this study is to determine Relationship of Total Cholesterol level with Incidence of Stroke on Patients who treated at inpatient ward Dr. M. Yunus Hospital Bengkulu. This study used survey analytic design with cross sectional method. Population in this study were all stroke patients who treated at Inpatient Ward Dr. M. Yunus Hospital Bengkulu in 2016 with the amount of 355 people who contain of 138 haemoragic stroke and 217 people with non haemorragic stroke. Sample in this study was 78 people who contain of 30 people patients with haemorragic stroke and 48 people with non haemorragic stroke obtained with proporsional simple random sampling technique. Collecting data in this study used secondary data who obtained from medical record at Inpatient Ward Dr. M. Yunus Hospital Bengkulu. The results of this study : there were 48 people (61,5%)  with non haemorragic stroke; there were 36 people (46,2%)  with high cholesterol levels, and there is significant relationship between total cholesterol level with Incidence of Stroke on patients who treated at Inpatient Ward Dr. M. Yunus Hospital Bengkulu with moderate category relationship. It was expected that health workers in Stroke Inpatient Room of RSUD M. Yunus Bengkulu especially nurses in order to provide more complete nursing care, especially in stroke patients. Keywords: cholesterol levels, patient, stroke


2018 ◽  
Vol 3 (2) ◽  
pp. 132
Author(s):  
Nunung Sri Mulyani ◽  
Agus Hendra Al Rahmad ◽  
Raudatul Jannah

Coronary heart disease generally occurs due to an increase in irregular cholesterol levels. Blood cholesterol is influenced by several factors, including genetic, gender, diet, obesity, and excessive coffee drinking. This study aims to determine the factors that influence blood cholesterol levels in outpatients with coronary heart disease at Meuraxa Regional Hospital. This study is a descriptive-analytical Case Control design, conducted in patients with coronary heart disease as many as 45 cases and 45 controls in May 2017 Data analysis using Chi-Square test. Diet data was collected using food recall, genetic data, sex collected by interview using questionnaires, nutritional status data collected through body mass index (BMI) measurements and cholesterol data collected through blood tests. Bivariate analysis showed a significant relationship between coffee consumption and total cholesterol levels with OR 2.768 (p = 0.033). There was no significant relationship between coffee consumption with HDL, LDL, and triglycerides (0.292; 0.088; 0.125). There was no significant correlation between genetic, gender, diet and nutritional status with levels of total cholesterol, LDL, HDL, and Triglycerides.T here is a significant relationship between coffee consumption and total cholesterol levels in patients with coronary heart disease, so it is necessary to limit coffee consumption for people with coronary heart disease.Penyakit jantung koroner umumnya terjadi karena peningkatan kadar kolesterol yang tidak teratur. Kolesterol darah dipengaruhi oleh beberapa faktor, diantaranya genetik, jenis kelamin, pola makan, obesitas, serta minum kopi yang berlebihan. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kadar kolesterol darah pada pasien rawat jalan penderita jantung koroner di RSUD Meuraxa. Penelitian deskriptif analitik berdesain Case Control, yang dilakukan pada  pasien penderita jantung koroner sebanyak 45 kasus dan 45 kontrol pada bulan Mei 2017. Analisis data menggunakan uji Chi-Square. Data pola makan dikumpulkan dengan menggunakan food recall, data genetik, jenis kelamin dikumpulkan dengan wawancara menggunakan kuisioner, data status gizi dikumpulkan melalui pengukuran indeks massa tubuh (IMT) dan data kolesterol dikumpulkan melalui pemeriksaan darah. Analisis bivariat  menunjukkan ada hubunganyang signifika konsumsi kopi dengan kadar kolesterol total dengan OR 2,768 (p= 0,033). Tidak ada hubungan yang signifikan konsumsi kopi dengan HDL, LDL dan trigliserida (0,292; 0,088; 0,125). Tidak ada hubungan yang signifikan genetik, jenis kelamin, pola makan dan status gizi dengan kadar kolesterol total, LDL, HDL dan Trgliserida. Ada hubungan yang signifikan konsumsi kopi dengan kadar kolesterol total pada penderita jantung koroner sehingga perlu kiranya pembatasan konsumsi kopi bagi penderita jantung koroner.


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