scholarly journals Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells

2013 ◽  
Vol 43 (6) ◽  
pp. 1999-2006 ◽  
Author(s):  
HONGMEI LUO ◽  
LU WANG ◽  
BRADLEY A. SCHULTE ◽  
AIMIN YANG ◽  
SHENGSONG TANG ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ionizing Radiation ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Premature Senescence ◽  
Radiation Induced

scholarly journals Triterpenoids from the Leaves of Centella asiatica Inhibit Ionizing Radiation-Induced Migration and Invasion of Human Lung Cancer Cells

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Ah-Reum Han ◽  
Sanghun Lee ◽  
Sujin Han ◽  
Yeon Jin Lee ◽  
Jin-Baek Kim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ionizing Radiation ◽  
Cancer Cells ◽  
Human Lung ◽  
Lung Cancer Cells ◽  
Human Lung Cancer ◽  
Migration And Invasion ◽  
Asiatic Acid ◽  
Human Lung Cancer Cells ◽  
Radiation Induced

Radiotherapy using ionizing radiation is a major therapeutic modality for advanced human lung cancers. However, ionizing radiation itself can induce malignant behaviors such as cancer cell migration and invasion, leading to local recurrence or distal metastasis. Therefore, safer and more effective agents that inhibit the metastatic behaviors of cancer cells in radiotherapy are needed. As a part of our ongoing search for new radiotherapy enhancers from medicinal herbs, we isolated the following triterpenoids from the ethanol extract of Centella asiatica: asiatic acid (1), madecassic acid (2), and asiaticoside (3). These compounds inhibited the ionizing radiation-induced migration and invasion of A549 human lung cancer cells at noncytotoxic concentrations. These results suggest that triterpenoids 1–3 isolated from C. asiatica are candidate natural compounds to enhance the effect of radiotherapy in patients with non-small-cell lung cancer.

scholarly journals MiR-34a modulates ionizing radiation-induced senescence in lung cancer cells

Oncotarget ◽  
2017 ◽  
Vol 8 (41) ◽  
pp. 69797-69807 ◽  
Author(s):  
Xiaoyuan He ◽  
Aimin Yang ◽  
Daniel G. McDonald ◽  
Ellen C. Riemer ◽  
Kenneth N. Vanek ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ionizing Radiation ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Radiation Induced

scholarly journals Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence

Lung Cancer ◽  
2013 ◽  
Vol 81 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Hongmei Luo ◽  
Caroline Yount ◽  
Hainan Lang ◽  
Aimin Yang ◽  
Ellen C. Riemer ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Premature Senescence ◽  
Radiation Induced

scholarly journals Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation

2005 ◽  
Vol 13 (1) ◽  
pp. 74-81 ◽  
Author(s):  
L Zhang ◽  
S Sharma ◽  
J M Hershman ◽  
G A Brent ◽  
S M Dubinett ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ionizing Radiation ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Genetically Modified ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Small Cell Lung
Sign in / Sign up

Export Citation Format

Share Document