Biocompatability of Precipitation-Enhancing Anodic Oxidation on Titanium as Implant Material

2007 ◽  
Vol 330-332 ◽  
pp. 593-596
Author(s):  
Keun Taek Oh ◽  
Kyoung Nam Kim ◽  
Dong Hoo Han ◽  
M.K. Chung ◽  
S.H. Hwang
Keyword(s):  
Cell Proliferation ◽  
Simulated Body Fluid ◽  
Physical Properties ◽  
Surface Topography ◽  
Anodic Oxidation ◽  
Body Fluid ◽  
The Novel ◽  
Machined Surface ◽  
Mtt Test ◽  
Fluid Cell

The composition of the electrolytes used in the process of anodic oxidation was modified to generate the novel anodic oxidation. The surface topography of the novel anodic oxidation showed that the pore/crater structures with the precipitants attached over the surface were observed in SEM. The physical properties and biocompatibility of the surface with the novel anodic oxidation were compared with that of anodic oxidation and machined surface of titanium. XRD, Bioactivity in a simulated body fluid, cell proliferation, and MTT test were performed to evaluate the differences among different surfaces.

In Vitro Apatite-Forming Ability of Titania Films Depends on Their Substrates

2007 ◽  
Vol 330-332 ◽  
pp. 633-636 ◽  
Author(s):  
T. Shozui ◽  
Kanji Tsuru ◽  
Satoshi Hayakawa ◽  
Akiyoshi Osaka
Keyword(s):  
Stainless Steel ◽  
Titanium Alloy ◽  
Simulated Body Fluid ◽  
Physical Properties ◽  
Silicon Wafer ◽  
Body Fluid ◽  
Sol Gel ◽  
Glass Slide ◽  
Titania Films

Titania films were coated by means of sol-gel method on various substrates such as titanium, titanium alloy, silicon wafer, stainless-steel, alumina, and glass slide where they coded as C5Ti, C5Ti6Al4V, C5Si, C5SUS, C5Al2O3 and C5GS, respectively. Their in vitro apatite-forming ability was examined with the Kokubo’s simulated body fluid (SBF; pH 7.4, 36.5°C). C5Ti, C5Ti6Al4V and C5Si deposited apatite particles on their surface within 7 days, whereas, C5SUS, C5Al2O3 and C5GS did not. These results implied that the in vitro apatite-forming ability of the titania films indirectly depended on the chemical or physical properties of the substrates.

Gap Effect on the Heterogeneous Nucleation of Apatite on Thermally Oxidized Titanium Substrate

2007 ◽  
Vol 361-363 ◽  
pp. 621-624 ◽  
Author(s):  
Atsushi Sugino ◽  
Keita Uetsuki ◽  
Kanji Tsuru ◽  
Satoshi Hayakawa ◽  
Chikara Ohtsuki ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Thermal Oxidation ◽  
Body Fluid ◽  
Mouth Opening ◽  
Titanium Substrate ◽  
Gap Effect ◽  
Apatite Formation ◽  
The Novel ◽  
Essential Condition ◽  
Novel Technique

Apatite formation on the surface of materials in body environment is an essential condition to show osteoconduction after implantation in bony defects. This study reports the novel technique for providing the apatite-forming ability to titanium metals by only controlling the spatial gap and thermal oxidation. Two pieces of titanium thermally oxidized at 400 °C were set together like V-letter with varied mouth opening. They showed the formation of apatite on both facing surface after exposure to a simulated body fluid (SBF) proposed by Kokubo and his colleagues, when the gap was less than approximately 600 μm. Moreover, specimens with micro-grooves of 500 μm in depth and 200-1000 μm in width was able to form apatite in SBF with in 7 days, after they were thermally oxidized at 400 oC. These results indicated that the titanium metals were provided with apatite-forming ability, i.e. osteoconduction, due to controlled gap with thermally oxidized surface. Hence, we conclude that bioactive titanium substrate showing osteoconduction can be produced by designed machining followed by thermal oxidation at an appropriate temperature.

Fabrication of Novel Hemostatic Film with Oxidized Cellulose and Sugar-Containing Hydroxyapatite

2018 ◽  
Vol 782 ◽  
pp. 84-90 ◽  
Author(s):  
Yeon Jeong Noh ◽  
Tomohiro Umeda ◽  
Yoshiro Musha ◽  
Kiyoshi Itatani
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Cellulose Nanofibers ◽  
Bone Diseases ◽  
Oxidized Cellulose ◽  
The Novel ◽  
Transparent Films

The novel hemostatic film for the surgery of bone diseases was fabricated using TEMPO(2,2,6,6-tetramethylpiperidine-1-oxyl)-oxidized cellulose nanofibers (TOCNs), and phosphoryl oligosaccharides of calcium (POs-Ca) or sugar-containing hydroxyapatite (s-Ca10(PO4)6(OH)2; s-HAp). Three kinds of the hydrophilic and transparent films with the thicknesses of 10 to 20 μm were fabricated, i.e., TOCN, POs-Ca-added TOCN and s-HAp-added TOCN films. Among these films, the uptake amount of the simulated body fluid by s-HAp-added TOCN film was as high as 5,543%, which was expected to quickly stop bleeding of larger amount of blood for the hemostasis.

scholarly journals In Vitro Cell Responses of MG-63 Osteoblast Cells on Bioactive Diopside and Wollastonite Nano-Bioceramics for Biomedical Applications

2020 ◽  
Author(s):  
Ruhollah Zamani Foroushani ◽  
Ebrahim Karamian ◽  
Mohammad Rafienia
Keyword(s):  
Cell Proliferation ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Biomedical Applications ◽  
Silicate Network ◽  
Osteoblast Cells ◽  
Alizarin Red ◽  
Cell Responses ◽  
The Stability

Abstract The present study aimed to synthesize and characterize diopside (CaMgSi2O6) and wollastonite (CaSiO3) nano-bioceramics via a combination of mechano-chemical and calcination processes. In vitro biomineralization and cell responses of wollastonite and diopside were performed on simulated body fluid (SBF) and MG-63 osteoblast cells. Results revealed proper tissue biomineralization of wollastonite and diopside through the generation of an apatite-like layer on the surface of nano-bioceramics. Cell responses of wollastonite and diopside eventuated non-cytotoxicity by MG-63 osteoblast cells, and their viability and cell proliferation were confirmed. Alizarin red staining of diopside and wollastonite evidenced great bioactivity and tissue biomineralization, and the ALP enzyme of diopside and wollastonite was enhanced in contact with the MG-63 osteoblast cells. Regarding the existence of Mg2+ in the calcium-silicate network and the stability network, diopside illustrated high biological and cell responses in comparison to wollastonite, and both of them were suggested as bioactive and biocompatible nano-bioceramics for biomedical applications.

scholarly journals Shape Matters: Crystal Morphology and Surface Topography Alter Bioactivity of Bioceramics in Simulated Body Fluid

2020 ◽  
Vol 22 (9) ◽  
pp. 2000044 ◽  
Author(s):  
Barbara Myszka ◽  
Philipp I. Schodder ◽  
Simon Leupold ◽  
Maïssa K. S. Barr ◽  
Katrin Hurle ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Surface Topography ◽  
Body Fluid ◽  
Crystal Morphology

ALCOA 2024

Alloy Digest ◽  
1998 ◽  
Vol 47 (3) ◽  
Keyword(s):  
Corrosion Resistance ◽  
Physical Properties ◽  
Surface Treatment ◽  
Tensile Properties ◽  
Surface Finish ◽  
High Strength ◽  
Machined Surface ◽  
2024 Alloy ◽  
Structural Applications ◽  
Strength Material

Abstract Alcoa 2024 alloy has good machinability and machined surface finish capability, and is a high-strength material of adequate workability. It has largely superseded alloy 2017 (see Alloy Digest Al-58, August 1974) for structural applications. The alloy has comparable strength to some mild steels. This datasheet provides information on composition, physical properties, and tensile properties. It also includes information on corrosion resistance as well as machining and surface treatment. Filing Code: AL-346. Producer or source: ALCOA Wire, Rod & Bar Division.

IN-VITRO BEHAVIOUR OF BIPHASIC CALCIUM PHOSPHATE WITH DIFFERENT RATIO OF SILICA CONTENT IN SIMULATED BODY FLUID

2015 ◽  
Vol 23 (1) ◽  
pp. 1-14
Author(s):  
Sudirman Sahid ◽  
◽  
Nor Shahida Kader Bashah ◽  
Salina Sabudin ◽  
◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Biphasic Calcium Phosphate ◽  
Silica Content

Phase evolution of hydroxapatite coatings suspension plasma sprayed using variable parameters in simulated body fluid

2010 ◽  
Vol 204 (8) ◽  
pp. 1236-1246 ◽  
Author(s):  
Romain d'Haese ◽  
Lech Pawlowski ◽  
Muriel Bigan ◽  
Roman Jaworski ◽  
Marc Martel
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Phase Evolution ◽  
Variable Parameters ◽  
Plasma Sprayed
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