Pilomatrix Carcinoma: Case Report of a Rare Cutaneous Malignancy with Unique Reconstructive Considerations

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Brandon K Richland ◽  
Khang T Nguyen
Keyword(s):  
Case Report ◽  
Cutaneous Malignancy ◽  
Pilomatrix Carcinoma

scholarly journals Pilomatrix Carcinoma in a Patient With Type 1 Myotonic Dystrophy: A Case Report

2020 ◽  
Vol 6 ◽  
pp. 2513826X1989883
Author(s):  
Sarah L. Zhu ◽  
David Choi ◽  
Jenny Santos ◽  
Bernard S. Jackson ◽  
Matthew McRae
Keyword(s):  
Case Report ◽  
Myotonic Dystrophy ◽  
Latissimus Dorsi ◽  
Myocutaneous Flap ◽  
Myotonic Dystrophy Type 1 ◽  
Myotonic Dystrophy Type ◽  
Genetic Condition ◽  
Latissimus Dorsi Myocutaneous Flap ◽  
Pilomatrix Carcinoma

This is the first report of pilomatrix carcinoma in a man with C282Y myotonic dystrophy type 1. This pilomatrix carcinoma had originally presented as a rapidly growing recurrence of a histopathologically confirmed pilomatrixoma, removed a year prior. On examination, the fungating mass had measured 10 × 23 cm. A wide local resection with removal of suspicious lymph nodes was preformed, and the resulting defect was reconstructed with a latissimus dorsi myocutaneous flap and skin graft. Histologic investigation of the excised mass confirmed the diagnosis of pilomatrix carcinoma. This is the first reported case of pilomatrix carcinoma in a patient with a genetic condition that often presents with scalp pilomatrixomas. Potential implications of myotonic dystrophy on developing pilomatrix carcinoma are discussed.

Management of Pilomatrix Carcinoma: A Case Report of Successful Treatment with Mohs Micrographic Surgery and Review of the Literature

2011 ◽  
Vol 37 (12) ◽  
pp. 1798-1805 ◽  
Author(s):  
Jeffrey M. Melancon ◽  
Wynnis L. Tom ◽  
Robert A. Lee ◽  
Michelle Jackson ◽  
Shang I. Brian Jiang
Keyword(s):  
Case Report ◽  
Successful Treatment ◽  
Review Of The Literature ◽  
Mohs Micrographic Surgery ◽  
Micrographic Surgery ◽  
Pilomatrix Carcinoma

scholarly journals Pilomatrix carcinoma on the left side of the parotid region: A case report and review of the literature

2015 ◽  
Vol 10 (1) ◽  
pp. 313-316 ◽  
Author(s):  
JI-FENG LIU ◽  
BIN LI ◽  
ZI-XUAN FAN ◽  
TING JIAO ◽  
CHAO LI ◽  
...  
Keyword(s):  
Case Report ◽  
Review Of The Literature ◽  
Parotid Region ◽  
Pilomatrix Carcinoma

scholarly journals Merkel cell carcinoma: a case report and literature review

2019 ◽  
Vol 2019 (11) ◽  
Author(s):  
Nicholas Mulchan ◽  
Alberto Cayton ◽  
Armand Asarian ◽  
Philip Xiao
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Surgical Excision ◽  
Merkel Cell ◽  
Cutaneous Malignancy ◽  
Uncommon Presentation ◽  
Prevalent Virus ◽  
Time Of Presentation

Abstract Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy of neuroendocrine origin presenting as a painless, rapidly growing nodule. MCC often presents in elderly, fair-skinned individuals in sun-exposed areas. Diagnosis is often overlooked at time of presentation due to its rarity, but MCC is twice as deadly as malignant melanoma. There has been bigger interest in the disease due to increasing incidence and an association with the prevalent virus Merkel cell polyomavirus. This study describes an uncommon presentation of MCC as a right gluteal lesion in an Afro-Panamanian patient. The tumor was suspected to be fibrolipoma, but Immunohistochemistry revealed the diagnosis of MCC, as stains for CD56 and CK20 were positive. In addition to surgical excision, the patient was referred for adjuvant radiotherapy. This case report and literature review elucidates the clinical, histopathologic and management aspects of MCC, which will help in recognizing and treating these tumors.

scholarly journals Scrofula Mimicking Cutaneous Malignancy: A Rare Case Report

2014 ◽  
Vol 6 (2) ◽  
pp. 68-70
Author(s):  
MK Garg ◽  
Uma Garg ◽  
Ritika Batra ◽  
Neha Salaria
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Drug Susceptibility ◽  
Common Disease ◽  
Isolation And Identification ◽  
Cutaneous Malignancy ◽  
Rare Case Report ◽  
Long Time ◽  
The Right ◽  
Bacterium Tuberculosis

ABSTRACT Since a long time scrofuloderma (SCF) was thought to be a common disease of childhood and was attributable to Myco bacterium tuberculosis. In 1951, a new entity nontuberculous scrofuloderma was described and it is caused by atypical mycobacteria namely Mycobacterium scrofulaceum. The clinical picture closely mimics tuberculous scrofuloderma but diagnosis should be established through culture isolation and identification, because drug susceptibility may be different in these cases. In this article, we report a case of a 22-year-old pregnant female patient who presented to us with scrofulaceous lesion on the right side of neck. How to cite this article Garg U, Batra R, Salaria N, Garg MK. Scrofula Mimicking Cutaneous Malignancy: A Rare Case Report. Int J Otorhinolaryngol Clin 2014;6(2):68-70.

Pilomatrix carcinoma: case report and review of literature

Pathology ◽  
2001 ◽  
Vol 33 (2) ◽  
pp. 248-251 ◽  
Author(s):  
Ruma Dutta ◽  
Ross Boadle ◽  
Thomas Ng
Keyword(s):  
Case Report ◽  
Review Of Literature ◽  
Pilomatrix Carcinoma

scholarly journals Pilomatrixoma with Atypical Features: A Case Report

2021 ◽  
pp. 98-102
Author(s):  
Meina Missak ◽  
Aaron Haig ◽  
Manal Gabril
Keyword(s):  
Case Report ◽  
Malignant Transformation ◽  
Mitotic Rate ◽  
High Power Field ◽  
Atypical Features ◽  
High Local Recurrence Rate ◽  
Hair Matrix ◽  
Malignant Changes ◽  
Pilomatrix Carcinoma

Pilomatrixoma is an uncommon, benign tumor with differentiation towards both the hair matrix and cells arising in the cortex, most frequently appearing in the first or second decade of life. In rare instances, pilomatrixomas can show malignant transformation. Pilomatrix carcinoma is extremely uncommon and has traditionally been considered a tumor of low malignant potential; however, a high local recurrence rate has been reported. There is a paucity of literature on these lesions, with only a few reports describing the spectrum of malignant changes seen in these lesions. In this case report, we present a case of pilomatrixoma in an adult patient showing atypical features. While the tumor is small, there are focal features that suggest progression to malignancy, but do not fulfill the criteria for pilomatrix carcinoma. These focal atypical features include a focal infiltrative pattern at the periphery, with a variable cytological atypia and an increased mitotic rate, up to five mitotic events/high-power field. Irregular foci of central necrosis (comedonecrosis) were present in several lobules. Some of the features identified were similar to a subset of pilomatrixoma, known as “proliferating pilomatrixoma.” However, our case did not have the diffuse changes or larger size that has been frequently reported in “proliferating pilomatrixoma.” In conclusion, given the lack of focality of the changes, the lesion in our case is best described as a pilomatricoma with atypical features. Furthermore, our case may highlight the need to ensure close clinical follow-up for these lesions with unexpected atypical features that raise concern of recurrence and malignant transformation.

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