scholarly journals Role of Brainstem Evoked Response Audiometry in Evaluating Sensorineural Hearing Loss in Diabetic Patients

2021 ◽  
Vol 29 (2) ◽  
pp. 182-188
Author(s):  
Deepika Goswami ◽  
Saurabh Srivastava ◽  
Anuja Bhargava ◽  
Syed M Faiz ◽  
Zeba Siddiqi ◽  
...  

Introduction Diabetes has become a global epidemic. Hearing loss has been long associated with diabetes. Brainstem Evoked Response Audiometry (BERA) is an objective, non-invasive, electro diagnostic test that not only evaluates the functional integrity of the subcortical auditory pathway but also provides topo-diagnosis of hearing loss. This study aims to identify the role BERA in detecting hearing loss early in diabetic patients.Materials and Methods In this study a total of 210 patients were taken and subjected to blood glucose levels followed by PTA were divided into two groups. Group I (n=105) consisted of diabetic patients with sensorineural hearing loss (SNHL) and Group II (n=105) had age and sex matched non-diabetics with SNHL. All the patients were evaluated with BERA.Results All the patients were subjected to Brain Stem Evoked Response Audiometry (BERA). Absolute latency of Wave I, III, V, I-III, III-V and I-V were assessed for both the ears. In both ear Absolute latency were significantly higher in diabetics as compared to non-diabetic patientsConclusion The findings of present study showed that the severity of hearing loss was significantly higher in diabetic patients as compared to non-diabetic controls. Level of glycemic control showed a possible link with severity of hearing loss.

Author(s):  
Shanthimalar R. ◽  
Muthuchitra S. ◽  
Mary Nirmala S. ◽  
Udhaya Chandrika G. ◽  
Mohamed Rasith H.

<p><strong>Background: </strong>Diabetes mellitus (DM) which is prevalent in world is associated with sensorineural hearing loss. Brainstem evoked response audiometry (BERA) is a simple, non-invasive procedure to detect early impairment of acoustic nerve and auditory pathway. The present study is under taken to evaluate the impact of DM on BERA parameters. Aim of the study was to compare the BERA of diabetic patients to those of age and gender matched controls to assess the involvement of central auditory pathway.</p><p><strong>Methods</strong>: A cross sectional study was conducted on 35 diabetic patients, aged 35 to 55 years, who were on treatment for at least 2 years, and 35 age and sex matched control participants, were subjected for BERA at 70,80 and 90 dB. The waveforms, absolute latency of wave I, wave III, wave V and interwave/ inter peak latency of I-III, III-V and I-V were analyzed with respect to both groups.</p><p><strong>Results</strong>: The absolute latency of wave III and wave V, interpeak/ interwave latency of I-III, interpeak/ interwave latency of I-V, III-V and absolute latency of wave V were highly significant at corresponding tested stimuli in the diabetic group compared to the control group.</p><p><strong>Conclusions</strong>: Early involvement of central auditory pathway in diabetic patients, can be detected with fair accuracy with auditory evoked potential studies; if done on a regular basis warrants meticulous glycemic control and prevents further damage.</p>


2021 ◽  
Vol 9 (04) ◽  
pp. 174-180
Author(s):  
Ubaid Ullah Wani ◽  
◽  
Sheikh Quyoom Hussain ◽  
Khursheed Ahmad Wani ◽  
◽  
...  

Background:Post meningitis hearing impairment is an important public health problem. Neonatal meningitis is an important cause of mortality and morbidity in neonates in future life. An important consequence is hearing loss. Hearing plays a basic and important role in language, speech and intellectual development. Late detection causes irreversible stunting of the language development potential of the child. Early detection and intervention would help to maximize linguistic competence and literacy development for children who are deaf or hard of hearing. The study of brainstem evoked response audiometry provides an opportunity to evaluate the functional integrity of auditory pathway from inner ear to upper brainstem. Aim:This study was conducted to determine the incidence of sensorineural hearing loss following meningitis in neonates. Material and Methods:The present study was conducted in the Department of Pediatrics, Government Medical College Srinagar. All the patients,Term neonates with CSF culture proven bacterial meningitis. , were referred to the Department of ENT, SMHS Hospital Srinagar, of the institution for thorough ENT checkup, to exclude any ear pathology and BERA (Brainstem Evoked Response Audiometry). Results:In our study total number of cases were 87. Majority of our studied children i.e. 47 (54%) were < days of age whereas 40 (46%) children were 8-28 days of aged. The mean age of our study patients was 15.7+3.71.Out of 87 patients in our study, male predominance was observed with 55.2% males versus 44.8% females with a male to female ratio of 1.2:1. Hearing loss was observed in 11 (12.6%) of our study children.Bilateral hearing loss was seen in 5 of the 11 children (5.7%) while as unilateral hearing loss was observed in 6 of the 11 children (6.9%). Out of a total of 11 (12.6%) patients who had hearing loss, 6 (6.9%) were having mild hearing loss, followed by 3 (3.4%) children with profound hearing loss while as moderate and severe hearing loss was observed in 1 (1.1%) patients each. Conclusion: Hearing loss is not a rare complication asociated with meningitis in neonates, early detection and appropriate treatment is needed to prevent language , speech and intellecual damage.


2017 ◽  
Vol VOLUME 5 (VOLUME 5 NUMBER 2 JULY 2017) ◽  
pp. 11-14
Author(s):  
Ankur Wats

INTRODUCTION: The Prevalence of Diabetes Melilites Is Increasing All Over the World Particularly in The Developing Countries. Diabetes Is Associated with Hearing Impairment Which Has Been Described as Sensorineural in Origin, But Evidence Favoring a Specific Mechanism Is Insufficient. Brainstem Evoked Response Audiometry Is a Simple, Non-Invasive Procedure to Detect Early Impairment of Acoustic Nerve and Auditory Pathway, Even in The Absence of Specific Symptoms. The Present Study Is Under Taken to Evaluate the Impact of Type 2 Diabetes Mellitus on BERA Parameters. OBJECTIVES: To Analyze and Compare the Brainstem Evoked Response Audiometry in Diabetic Patients and Age and Gender Matched Controls. METHODS: 40 Type 2 Diabetic Patients Attending Outpatient Department of Otorhinolaryngology and Medicine, C. S. S. Hospital, Meerut and 40 Non Diabetic Age and Gender Matched Subjects from General Population Were Selected Randomly, With None of Them Having Complains of Hearing Loss and Were Subjected to Brainstem Evoked Response Audiometry (BERA). BERA Parameters Such as Latency of Wave I, II, III, IV, And V; Inter-Peak Latencies I-III, I-V and III-V Were Analyzed. BERA Parameters Were also assessed according to The Duration of Diabetes and Fasting Blood Glucose Levels. RESULTS: Patients with Type 2 Diabetes Mellitus Were Found to Have Subclinical Hearing Impairment as Revealed by Impaired Auditory Brainstem Response. In This Study Diabetic Patients Showed a Statistically Significant (p value<0.05) Delay in The Latency of Waves I, III and V and Inter-Peak Latency of Waves I-III, I-V and III-V When Compared to Controls. There Was a Positive Correlation Between Prolongation of Latencies and Duration of Diabetes Mellitus. The Latencies Were Also Found to Be Prolonged with altered blood glucose levels. CONCLUSION: The present study correlates with earlier findings that impaired BERA response in diabetic patients is a consequence of microangiopathy. Meticulous control of blood sugar levels is a must to prevent the early complications of diabetes, so that further damage to auditory pathway can be prevented. KEY-WORDS: Diabetes mellitus; Hearing; Brainstem evoked response audiometry (BERA).


2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Semiramis Zizlavsky ◽  
Ronny Suwento ◽  
Dina Alia

Background: Leopard syndrome is a rare case, only around 200 cases has been reported worldwide.  Leopard syndrome is abbreviation for multipel Lentigines, Electrocardiographic conduction, Ocular hypertelorism, Pulmonary stenosis, Abnormality of genitalia, Retardation of growth, and sensorineural Deafness. This disorder suggests a possible relation between PTPN11 gene mutations and distinct clinical features. Purpose: This case is presented so that ENT specialists could identify signs and symptoms of Leopard Syndrome which manifest as sensorineural hearing loss (SNHL). Case: We report a 29 year old woman with multiple lentigines, scoliosis and atrial septal defect. She has 4 year old twin boys, one of them has cryptorchidism and a 10 month old girl with asymmetric septal hypertrophy and they also have multipel lentigines. They were referred to ENT Department for auditory function screening since  Leopard syndrome is suspected. The audiometry of the mother reveals mild conductive deafness (40 dB)  in right ear due to tympanic membrane perforation. Audiometry of the twin boys reveals sensorineural hearing loss above 4000 Hz frequency. Brainstem Evoked Response Audiometry (BERA) of the daughter reveals mild sensorineural hearing loss (40 dB )on right ear. Genogram shows that the disorders is dominant autosomal inherited. Management: Periodic auditory examination for sensorineural hearing loss is recommended since delayed onset could occur. Conclusion: Sensorineural hearing loss is a mani-festation of Leopard syndrome that should be assessed early and periodically to detect delayed onset. Keywords: Sensorineural hearing loss (SNHL), Leopard syndrome, generalized lentiginosa.    Abstrak :  Latar belakang: Sindroma Leopard merupakan kasus yang jarang ditemukan dan dari publikasi yang ada, hingga saat ini hanya terdapat 200 kasus di seluruh dunia. Sindroma Leopard merupakan singkatandari Lentigines multipel, Electrocardiographic conduction, Ocular hypertelorism, Pulmonary stenosis,Abnormality of genitalia, Retardation of growth and sensorineural Deafness. Kelainan ini disebabkan olehmutasi gen PTPN11 dengan gambaran klinis yang khas. Tujuan: Kasus ini diajukan agar spesialis THTmengenali gejala sindroma Leopard yang dapat melibatkan gangguan pendengaran berupa sensorineuralhearing loss(SNHL) sehingga tidak terjadi keterlambatan dalam penatalaksanaan. Kasus: Perempuanberusia 29 tahun dengan lentiginosa multipel, skoliosis dan defek septum atrium. Ia memiliki 2 anaklaki-laki kembar yang salah satunya mengalami kriptorkismus dan anak perempuan usia 10 bulan yangmenderita hipertrofi septum asimetris dan juga menderita multipel lentiginosa. Mereka dikonsulkan ke THT dari bagian kulit RSCM untuk pemeriksaan fungsi pendengaran dengan kecurigaan sindromaLeopard. Pada pemeriksaan audiometri diperoleh hasil pada ibu berupa tuli konduktif ringan (40 dB)telinga kanan akibat perforasi membran timpani. Dua orang anak kembar menunjukkan hasil tuli sarafdi atas frekuensi 4000 Hz. Pemeriksaan Brainstem Evoked Response Audiometry (BERA) pada anakperempuan menunjukkan tuli saraf ringan (40 dB) di telinga kanan. Genogram menunjukkan kelainanautosom dominan. Penatalaksanaan: Tindak lanjut berupa pemeriksaan pendengaran secara berkaladianggap penting untuk mendeteksi terjadinya awitan lambat. Kesimpulan: SNHL merupakan salah satumanifestasi sindroma Leopard yang perlu diperiksa untuk mendeteksi terjadi awitan lambat. Kata kunci: Sensorineural hearing loss (SNHL), sindroma Leopard, lentiginosa multipel.


2020 ◽  
Vol 15 (1) ◽  
pp. 884-889
Author(s):  
İbrahim Özcan ◽  
İbrahim Hira ◽  
Altan Kaya ◽  
Mehmet Yaşar ◽  
Murat Doğan ◽  
...  

AbstractBackgroundWe aimed to evaluate the association between mean platelet volume, platelet distribution width (PDW), platelet count (PC) and plateletcrit (PCT), and the presence of sudden sensorineural hearing loss (SSNHL) and treatment response. In the literature, there is no study that investigates the platelet functions in diabetic patients with SSNHL.MethodsThe patients were retrospectively assigned into Group 1 (68 diabetic patients with SSNHL), Group 2 (63 nondiabetic patients with SSNHL) and Group 3 (64 healthy controls).ResultsPC was not significantly different between the groups (p > 0.05). MPV, PDW and PCT values were significantly higher in Group 1 as compared to Groups 2 and 3 (p < 0.05). Platelet parameters were not significantly different between the patients who were responsive and nonresponsive to the treatment. Therefore, the platelet parameters did not affect prognosis significantly in this study samples (p > 0.05).ConclusionsThis study showed that platelet parameters did not have a significant effect as a prognostic and predictive value in diabetic and nondiabetic patients with SSNHL. Further studies with more homogenous and larger study groups investigating the platelet parameters are needed to demonstrate microvascular damage and vascular alterations induced by diabetes mellitus.


2020 ◽  
Vol 27 (12) ◽  
pp. 2729-2733
Author(s):  
Rabia Saleem Safdar ◽  
M Faisal Mehar ◽  
Madiha Naz ◽  
Afsheen Asghar Khan ◽  
Nusrat Buzdar ◽  
...  

Objectives: To determine the frequency of sensorineural hearing loss (SNHL) in children with bacterial meningitis. Study Design: Cross Sectional study. Setting: Department of Paediatric Medicine Nishtar Hospital, Multan. Period: October 2019 to March 2020. Material & Methods: The study was conducted after permission from ethical committee. A total of 151 patients admitted with bacterial meningitis were enrolled. Apart from the presenting complaints, necessary information like the age and gender were noted. Examination of the child was done to assess the condition of child. Brainstem evoked response audiometry (BERA) test was performed before discharge of the patient from the hospital. The outcome variable that is SNHL in bacterial meningitis assessed by BERA test was noted in a specifically designed Performa. Results: Out of total of 151 patients, males were 83 (55%) while females 68 (45%). Overall mean age was 11.85+6.12 months. SNHL was found in 26 (17.2%) children. There was no significant effect of age or gender on the frequencies of SNHL. Conclusion: SNHL is a frequently encountered complication in our population of children with bacterial meningitis. SNHL should be carefully sought out and properly diagnosed in all the patients presenting with bacterial meningitis.


Author(s):  
C. R. Vijay Bharath Reddy ◽  
M. Santhosh Reddy ◽  
K. Suresh

<p class="abstract"><strong>Background:</strong> There are no published studies that compared amplitude of stacked-Tone ABR and Chirp ABR in hearing impaired individuals with sensorineural hearing loss, which need to be investigated. Objective of the study was to know whether amplitude of standard chirp evoked ABR is same as tone burst evoked stacked ABR in individuals with normal hearing listeners and individuals with sensorineural hearing loss.</p><p class="abstract"><strong>Methods:</strong> Present hospital based cross sectional study was carried out at Malla Reddy Institute of Medical Sciences, from January 2016 to December 2016. Two groups of subjects were taken. Group I consisted of 20 ears (14 males and 6 females) with normal hearing. Group II consisted of 20 ears (11 females and 9 males) with cochlear hearing loss.  </p><p class="abstract"><strong>Results:</strong> Wave V Amplitude of stacked tone ABR was higher than Chirp stimuli evoked ABR wave V in both the groups. Amplitude of stacked tone ABR and chirp was smaller for individuals with sensorineural hearing loss than normal hearing. Between the 2 chirp stimuli, standard Chirp ABR amplitude was higher than modified Chirp in normal hearing listeners and individual with sensorineural hearing loss. For modified chirp in individuals with normal hearing and cochlear hearing loss. Latency obtained by standard chirp was longer compared to latency obtained by modified chirp, which is seen in both the groups.</p><p><strong>Conclusions:</strong> Chirp ABR may be opted over stacked tone ABR in neurological investigations due to its lesser variability in amplitude and shorter duration of testing. </p>


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Maria Francisca Colella-Santos ◽  
Thaís Antonelli Diniz Hein ◽  
Gabriele Libano de Souza ◽  
Maria Isabel Ramos do Amaral ◽  
Raquel Leme Casali

The aim was to describe the outcome of neonatal hearing screening (NHS) and audiological diagnosis in neonates in the NICU. The sample was divided into Group I: neonates who underwent NHS in one step and Group II: neonates who underwent a test and retest NHS. NHS procedure was automated auditory brainstem response. NHS was performed in 82.1% of surviving neonates. For GI, referral rate was 18.6% and false-positive was 62.2% (normal hearing in the diagnostic stage). In GII, with retest, referral rate dropped to 4.1% and false-positive to 12.5%. Sensorineural hearing loss was found in 13.2% of infants and conductive in 26.4% of cases. There was one case of auditory neuropathy spectrum (1.9%). Dropout rate in whole process was 21.7% for GI and 24.03% for GII. We concluded that it was not possible to perform universal NHS in the studied sample or, in many cases, to apply it within the first month of life. Retest reduced failure and false-positive rate and did not increase evasion, indicating that it is a recommendable step in NHS programs in the NICU. The incidence of hearing loss was 2.9%, considering sensorineural hearing loss (0.91%), conductive (1.83%) and auditory neuropathy spectrum (0.19%).


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