Evaluation of the Response of Odontogenic Keratocysts to Tube Decompression: A Clinical and Radiographic Study
Background and Objectives: Keratocyst is the most aggressive entity of odontogenic cysts with a high tendency to recure after enucleation. This study was conducted to assess the effect of decompression in inducing cyst shrinkage before enucleation. Materials and Methods: A prospective non-randomized study was conducted on 11 patients with odontogenic keratocyst the department of maxillofacial surgery, university-affiliated teaching hospital, between February 2016 to March 2021. There were 8 males and 3 females, with a mean age of 57 years. Tube decompression was conducted as a preliminary treatment, before enucleation. The size of the cyst was measured on orthopantomograph, before, during, and after decompression. The percentage of reduction was calculated, as well as, the correlation of cyst regression with the initial size of the lesion and age of the patient. Results: The mean duration time of decompression was 208 days (152-316). The pre- and post-decompression size of the cysts was 14.51 cm2 (5.63 cm2 -32.37 cm2) and 6.69 cm2 (1.76 cm2-14.81 cm2), respectively. The total and monthly percentage of reduction in the size of the cysts was 54.39% (37.29%-76.37%) and 7.84% (4.45%-11.27%), respectively. The initial size of the lesion has no significant correlation with the percentage of reduction, whereas the age of the patients showed a significant negative correlation with the percentage of reduction. Conclusion: Decompression is a well-tolerated conservative treatment, which leads to marked reduction in cyst dimensions. It induces shrinkage of the cyst away from anatomical structures, to reduce the morbidity associated with subsequent surgical treatment.