scholarly journals Adverse effects of chronic low dose-rate gamma-ray exposure ameliorated by environmental enrichment in mice

2021 ◽  
Vol 19 (3) ◽  
pp. 543-550
Author(s):  
D. Takai ◽  
A. Abe ◽  
H. Miura ◽  
I.B. Tanaka ◽  
M. Saito ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Dose Rate ◽  
Environmental Enrichment ◽  
Low Dose ◽  
Gamma Ray ◽  
Low Dose Rate

scholarly journals Establishment of a low dose rate gamma ray calibration field for environmental radiation monitoring devices

2019 ◽  
Vol 186 (4) ◽  
pp. 538-538
Author(s):  
Munehiko KOWATARI ◽  
Hiroshi YOSHITOMI ◽  
Sho NISHINO ◽  
Yoshihiko TANIMURA ◽  
Tetsuya OHISHI ◽  
...  
Keyword(s):  
Dose Rate ◽  
Low Dose ◽  
Gamma Ray ◽  
Radiation Monitoring ◽  
Environmental Radiation ◽  
Low Dose Rate ◽  
Monitoring Devices

scholarly journals Association between low doses of ionizing radiation, administered acutely or chronically, and time to onset of stroke in a rat model

2020 ◽  
Vol 61 (5) ◽  
pp. 666-673
Author(s):  
Norio Takahashi ◽  
Munechika Misumi ◽  
Hideko Murakami ◽  
Yasuharu Niwa ◽  
Waka Ohishi ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Dose Rate ◽  
Low Dose ◽  
Gamma Ray ◽  
Spontaneously Hypertensive Rat ◽  
Onset Time ◽  
High Sensitivity ◽  
Low Dose Rate ◽  
Model Animal

Abstract Exposure to high-doses of ionizing radiation has been reported to be associated with the risk of stroke. However, risks associated with lower dose exposures remain unclear, and there is little information available for the risk modification according to the dose-rate. There are few studies using animal models which might be able to provide complementary information on this association. In this study, the male stroke-prone spontaneously hypertensive rat (SHRSP) was used as a model animal. The rats were acutely irradiated with doses between 0 and 1.0 Gy or chronically irradiated with a cumulative dose of 0.5 or 1.0 Gy (at a dose rate of 0.05 or 0.1 Gy/day, respectively). The onset time of stroke related symptoms in SHRSP was used as an endpoint for evaluating the effects of low dose and the low dose-rate gamma-ray exposures. With respect to acute exposure, the time to the onset of stroke in the irradiated rats suggested the presence of a threshold around 0.1 Gy. For the low dose-rate chronically exposed, no significant increase in stroke symptom was observed. These findings are novel and demonstrate that the SHRSP system can be used to determine the association between the risk of stroke and radiation exposure with high sensitivity. Moreover, these studies provide important information regarding the association between the low dose and low dose-rate radiation exposure and circulatory diseases, especially stroke.

scholarly journals Comparative response of dogs and monkeys to sublethal acute and continuous low dose-rate gamma-ray exposure

1977 ◽  
Author(s):  
J.F. Spalding ◽  
L.M. Holland ◽  
O.S. Johnson ◽  
P.M. LaBauve ◽  
J.E. London ◽  
...  
Keyword(s):  
Dose Rate ◽  
Low Dose ◽  
Gamma Ray ◽  
Low Dose Rate ◽  
Comparative Response
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