scholarly journals Clinical Study of Memory Disorders in Aging Patients and Associated Pathology

2021 ◽  
pp. 1-10
Author(s):  
Castejón OJ ◽  
Carrero Gonzalez CM ◽  
Lastre G ◽  
Galindez P ◽  
Salones de Castejón M ◽  
...  
Keyword(s):  
Clinical Study ◽  
Cardiovascular Diseases ◽  
Metabolic Diseases ◽  
Pathological Condition ◽  
Cervicogenic Headache ◽  
Memory Disorders ◽  
Gastrointestinal Pathology ◽  
Loss Of Weight ◽  
Hearing Acuity ◽  
Gait Disturbances

We have observed semantic memory and episodic memory disorders in patients ranging from 40 to 92 years-old (100%), with associated cardiovascular diseases and blood hypertension (82%), sleep disorders (50%), neurobehavioral disorders (44%), such as depression, anxiety, aggression, and vascular demencia, disorders of language (36%), neurosensory disorders (28%), as diminution of visual and hearing acuity, dizziness (26%), Parkinson disease (34%), Alzheimer disease (21%), gait disturbances (10%), vertigo (10%), cervicalgia and cervicogenic headache (10%) trigeminal neuralgia (2%), We found as comorbidities the following non-nervous diseases: metabolic diseases as diabetes (21%) and hypothyroidism (5%), gastrointestinal pathology (21%), such as constipation, loss of sphincter control, and gastritis, arthritis (13%), prostatic hypertrophy (1%) and loss of weight (1%). A detailed discussion of every pathological condition is provided.

scholarly journals “Clinical Study of Memory Disorders in Aging Patients with Associated Cardiovascular, Neurological, Neurobehavioral and Metabolic Diseases”. A Review

2021 ◽  
pp. 1-9
Author(s):  
Castejón OJ ◽  
◽  
Carrero-González Carmen Maria ◽  
Keyword(s):  
Cardiovascular Diseases ◽  
Parkinson Disease ◽  
Sleep Disorders ◽  
Metabolic Diseases ◽  
Cervicogenic Headache ◽  
Memory Disorders ◽  
Gastrointestinal Pathology ◽  
Loss Of Weight ◽  
Hearing Acuity ◽  
Neurobehavioral Disorders

We have observed semantic memory and episodic memory disorders (100%) in patients ranging from 40 to 92 years-old, associated to cardiovascular diseases and blood hypertension (82%), sleep disorders (50%), neurobehavioral disorders (44%), such as depression, anxiety, aggression, and vascular demencia, disorders of language (36%), neurosensory disorders (28%), as diminution of visual and hearing acuity, dizziness (26%), Parkinson disease (34%), Alzheimer disease (21%), gait disturbances (10%), vertigo (10%), cervicalgia and cervicogenic headache (10%) trigeminal neuralgia (2%,), We observed as comorbidities the following non-nervous diseases: metabolic diseases as diabetes (21%) and hypothyroidism (5%), gastrointestinal pathology (21%), such as constipation, loss of sphincter control, and gastritis, arthritis (13%), prostatic hypertrophy (1%) and loss of weight (1%). We consider that according to their high frequency the most risk factors associated to memory disorders are cardiovascular diseases and blood hypertension (82%), sleep disorders (50%), neurobehavioral disorders (44%), such as depression, anxiety, aggression, and vascular demencia, disorders of language (36%), neurosensory disorders (28%), as diminution of visual and hearing acuity, dizziness (26%), and Parkinson disease (34%).

scholarly journals “Clinical Study of Memory Disorders in Aging Patients with Associated Cardiovascular, Neurological, Neurobehavioral and Metabolic Diseases”. A Review

2021 ◽  
Vol 3 (2) ◽  
pp. 1-9
Author(s):  
Carrero-González Carmen Maria ◽  
◽  
Castejón OJ ◽  
Judith Cristina Martínez Royert ◽  
◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Parkinson Disease ◽  
Sleep Disorders ◽  
Metabolic Diseases ◽  
Cervicogenic Headache ◽  
Memory Disorders ◽  
Gastrointestinal Pathology ◽  
Loss Of Weight ◽  
Hearing Acuity ◽  
Neurobehavioral Disorders

We have observed semantic memory and episodic memory disorders (100%) in patients ranging from 40 to 92 years-old, associated to cardiovascular diseases and blood hypertension (82%), sleep disorders (50%), neurobehavioral disorders (44%), such as depression, anxiety, aggression, and vascular demencia, disorders of language (36%), neurosensory disorders (28%), as diminution of visual and hearing acuity, dizziness (26%), Parkinson disease (34%), Alzheimer disease (21%), gait disturbances (10%), vertigo (10%), cervicalgia and cervicogenic headache (10%) trigeminal neuralgia (2%,), We observed as comorbidities the following non-nervous diseases: metabolic diseases as diabetes (21%) and hypothyroidism (5%), gastrointestinal pathology (21%), such as constipation, loss of sphincter control, and gastritis, arthritis (13%), prostatic hypertrophy (1%) and loss of weight (1%). We consider that according to their high frequency the most risk factors associated to memory disorders are cardiovascular diseases and blood hypertension (82%), sleep disorders (50%), neurobehavioral disorders (44%), such as depression, anxiety, aggression, and vascular demencia, disorders of language (36%), neurosensory disorders (28%), as diminution of visual and hearing acuity, dizziness (26%), and Parkinson disease (34%).

A new medical Internet system in healthcare: innovation of Telegeriatrics and healthcare demands of older patients of different age groups (Preprint)

2020 ◽  
Author(s):  
Yu Gong ◽  
Jianyuan Zhou
Keyword(s):  
Cardiovascular Diseases ◽  
General Practitioners ◽  
Older Patients ◽  
Metabolic Diseases ◽  
Treatment Plan ◽  
Age Groups ◽  
The Elderly ◽  
Diagnosis And Treatment ◽  
World Health ◽  
New Model

BACKGROUND Healthcare for older patients is a worldwide challenge for public health system. A new medical Internet system in healthcare which is a new model of telegeriatrics system has been established. The key innovation is the new telegeriatrics system was conducted jointly by general practitioners in the Community Health Service Center and specialists in university teaching hospital. Unlike the typical telemedicine that has been practiced in other countries, the new model provides a solution for the key issues in telemedicine where a doctor is unable to conduct a direct physical examination and the associated potential diagnostic error. OBJECTIVE This study is to introduce the operation mechanism of the new Telegeriatrics system and analyze healthcare demands of older patients in different age groups applying the new Telegeriatrics system. METHODS 472 older patients (aged≥60) were enrolled and divided into the young older group (aged 60 to 74), the old older group (aged 75 to 89) and the very old group (aged≥90) according to the age stratification of World Health Organization. Proportion of the top 10 diseases of older patients of different age groups was analyzed. RESULTS The process of older patients’ diagnosis and treatment made by specialist and general practitioners formed a closed loop. It ensures the timeliness and effectiveness of diagnosis and treatment of older patients. The treatment effect can be observed by general practitioners and specialist can adjust the treatment plan in time. In this study, it was found that older patients in different age groups have different healthcare demands. Coronary heart disease and type 2 diabetes mellitus were found to be the main diseases of the older patients and the young older patients as well as the old older patients applying Telegeriatrics. CONCLUSIONS The new telegeriatrics system can provide convenient and efficient healthcare services for older patients and overcome the disadvantage of currently used models of telegeriatrics. Older patients in different age groups have different medical care demands. Cardiovascular diseases and metabolic diseases have become the main diseases of the elderly applying the new Telegeriatrics system. Healthcare policy makers should invest more medical resources to the prevention of cardiovascular diseases and metabolic diseases in the elderly.

Anti-inflammatory Effects of Plant-based Foods and of their Constituents

2008 ◽  
Vol 78 (6) ◽  
pp. 293-298 ◽  
Author(s):  
Bernhard Watzl
Keyword(s):  
Cardiovascular Diseases ◽  
Bioactive Compounds ◽  
Pathological Condition ◽  
Wide Spectrum ◽  
Bioactive Constituents ◽  
Plant Foods ◽  
Whole Wheat ◽  
Markers Of Inflammation ◽  
Inflammatory Processes ◽  
Anti Inflammatory

Inflammation is a pathological condition underlying a number of diseases including cardiovascular diseases, cancer, and chronic inflammatory diseases. In addition, healthy, obese subjects also express markers of inflammation in their blood. Diet provides a variety of nutrients as well as non-nutritive bioactive constituents which modulate immunomodulatory and inflammatory processes. Epidemiological data suggest that dietary patterns strongly affect inflammatory processes. Primarily the intake of fruit and vegetables as well as of whole wheat is inversely associated with the risk of inflammation. In addition to observational studies there are also data from human intervention studies suggesting an anti-inflammatory potential of these plant foods. At the level of bioactive compounds occurring in plant foods, primarily carotenoids and flavonoids seem to modulate inflammatory as well as immunological processes. In conclusion, there is convincing evidence that plant foods and non-nutritive constituents associated with these foods modulate immunological and inflammatory processes. By means of anti-inflammatory activities a plant-based diet may contribute to the lower risk of cardiovascular diseases and cancer. A high intake of vegetables, fruit, and whole wheat as recommended by all international nutrition authorities provides a wide spectrum of bioactive compounds at health-promoting concentrations.

PENGARUH LATIHAN FISIK AEROBIK DENGAN INTENSITAS SEDANG TERHADAP KONDISI MAKROSKOPIK DAN GAMBARAN HISTOPATOLOGI MIOKARD MENCIT BALB/C

2019 ◽  
Vol 1 (2) ◽  
pp. 30
Author(s):  
Niswan Helja Batubara ◽  
Nova Sylviana ◽  
Hasrayati Agustina ◽  
Hadaral Hudanul Qolbi
Keyword(s):  
Physical Activity ◽  
Cardiovascular Diseases ◽  
Physical Exercise ◽  
Aerobic Exercise ◽  
Pathological Condition ◽  
Moderate Intensity ◽  
Control Group ◽  
Intensity Increase ◽  
Pathological Features ◽  
Histopathologic Features

Cardiovascular diseases is one of the non-communicable diseases that has been the leading cause of death compared to other causes. Actually, cardiovascular diseases can be prevented with avoiding the risk factors and lifestyle improvements such as doing physical exercise. Useful physical exercise according to according to The American College of Cardiology/American Heart Association (ACC/AHA) is a moderate intensity aerobic exercise conducted 30 minutes in time for 5 days a week. This research aims to study the effects of moderate intensity aerobic exercise on macroscopic conditions, histopathologic features of the myocardium of mice. This research using 35 male balb/c mice devided to 3 groups (control, physical activity, exercise). Variables in this research included duration of physical activity and exercise, macroscopic conditions, histopathologic features of the myocardium of balb/c mice. After 10 and 28 days of exposure, the heart were harvested. The macroscopic conditions, histopathologic features of the myocardium were examined. The weight of heart in physical activity group was greater than control group (p=0.009). Similarly, the weight of heart exercise group was also greater compared to control group (p=0.013). The histopathologic features in physical activity and physical exercise groups showed pathological features of myocardial infarction (p=0.242). While in the control group did not show pathological features. Aerobic physical activity moderate intensity increase the risk of pathological condition of heart in the form of myocardial infarct through the macroscopic conditions and histological features of myocardium. Meanwhile, exercise with moderate intensity affect the physiological hypertrophy of the myocardium.

scholarly journals Circulating Leukocytes and Oxidative Stress in Cardiovascular Diseases: A State of the Art

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Speranza Rubattu ◽  
Maurizio Forte ◽  
Salvatore Raffa
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Diseases ◽  
Stress Level ◽  
Mononuclear Cells ◽  
Pathological Condition ◽  
Clinical Manifestations ◽  
Therapeutic Interventions ◽  
Oxidative Stress Level ◽  
The Impact

Increased oxidative stress from both mitochondrial and cytosolic sources contributes to the development and the progression of cardiovascular diseases (CVDs), and it is a target of therapeutic interventions. The numerous efforts made over the last decades in order to develop tools able to monitor the oxidative stress level in patients affected by CVDs rely on the need to gain information on the disease state. However, this goal has not been satisfactorily accomplished until now. Among others, the isolation of circulating leukocytes to measure their oxidant level offers a valid, noninvasive challenge that has been tested in few pathological contexts, including hypertension, atherosclerosis and its clinical manifestations, and heart failure. Since leukocytes circulate in the blood stream, it is expected that they might reflect quite closely both systemic and cardiovascular oxidative stress and provide useful information on the pathological condition. The results of the studies discussed in the present review article are promising. They highlight the importance of measuring oxidative stress level in circulating mononuclear cells in different CVDs with a consistent correlation between degree of oxidative stress and severity of CVD and of its complications. Importantly, they also point to a double role of leukocytes, both as a marker of disease condition and as a direct contributor to disease progression. Finally, they show that the oxidative stress level of leukocytes reflects the impact of therapeutic interventions. It is likely that the isolation of leukocytes and the measurement of oxidative stress, once adequately developed, may represent an eligible tool for both research and clinical purposes to monitor the role of oxidative stress on the promotion and progression of CVDs, as well as the impact of therapies.

Comparative clinical study using laser and LED-therapy for orofacial pain relief: dentin hypersensitivity and cervicogenic headache

2015 ◽  
Author(s):  
Rosane F. Z. Lizarelli ◽  
Renata C. A. Pizzo ◽  
Fernando L. E. Florez ◽  
Clovis Grecco ◽  
Jose G. Speciali ◽  
...  
Keyword(s):  
Clinical Study ◽  
Pain Relief ◽  
Orofacial Pain ◽  
Cervicogenic Headache ◽  
Dentin Hypersensitivity ◽  
Comparative Clinical Study ◽  
Led Therapy

scholarly journals Gastroenterocardiology: Or what do the gut and the heart have in common?

2021 ◽  
Vol 46 (1) ◽  
pp. 11-22
Author(s):  
Zoran Joksimović ◽  
Dušan Bastać ◽  
Snežana Pavlović
Keyword(s):  
Cardiovascular Diseases ◽  
Gut Microbiota ◽  
Metabolic Diseases ◽  
Chronic Inflammatory Bowel Disease ◽  
Nonalcoholic Fatty Liver ◽  
Inflammatory Bowel ◽  
The Impact ◽  
The Relationship ◽  
Gut Microbiota Composition

The gut microbiota of our organism is a community of bacteria, archaea, fungi, viruses and parasites that make up a unique ecosystem in the digestive tract, which consists of about 1014 microorganisms. The diversity of this community between individuals occurs because of the differences in the host genome and the impact of environmental factors, including hygiene, diet, lifestyle and the use of different drugs. Significant evidence suggests that changes in the microbiota could play a role in cardiovascular diseases. The results of research papers for the last two decades have confirmed that altered gut microbiota composition (dysbiosis) contributes to the development of various diseases, including cardiovascular diseases, type 2 diabetes, chronic kidney disease, nonalcoholic fatty liver disease, chronic inflammatory bowel disease and even certain types of cancer. There is growing evidence that in the future, apart from current predisposing factors for cardiovascular and metabolic diseases, including genetic, environmental and lifestyle factors, one should count on new risk factors such as nutritional disproportion and gut dysbiosis. Thus, we look upon the relationship between the gastrointestinal tract and cardiovascular system, i.e. the "gut-heart axis" in a new way.

scholarly journals Effects of REDOX in Regulating and Treatment of Metabolic and Inflammatory Cardiovascular Diseases

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Kai Wang ◽  
Yanhan Dong ◽  
Jing Liu ◽  
Lili Qian ◽  
Tao Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Diseases ◽  
Metabolic Diseases ◽  
Kidney Diseases ◽  
Cardiac Metabolism ◽  
Cardiac Diseases ◽  
Enzymatic Reactions ◽  
Metabolic Dysfunction ◽  
Ros Signalling

Reduction oxidation (REDOX) reaction is crucial in life activities, and its dynamic balance is regulated by ROS. Reactive oxygen species (ROS) is associated with a variety of metabolic diseases involving in multiple cellular signalling in pathologic and physiological signal transduction. ROS are the by-products of numerous enzymatic reactions in various cell compartments, including the cytoplasm, cell membrane, endoplasmic reticulum (ER), mitochondria, and peroxisome. ROS signalling is not only involved in normal physiological processes but also causes metabolic dysfunction and maladaptive responses to inflammatory signals, which depends on the cell type or tissue environment. Excess oxidants are able to alter the normal structure and function of DNA, lipids, and proteins, leading to mutations or oxidative damage. Therefore, excessive oxidative stress is usually regarded as the cause of various pathological conditions, such as cancer, neurodegeneration, cardiovascular diseases (CVDs), diabetes, and kidney diseases. Currently, it has been possible to detect diabetes and other cardiac diseases by detecting derivatives accompanied by oxidative stress in vivo as biomarkers, but there is no effective method to treat these diseases. In consequence, it is essential for us to seek new therapy targeting these diseases through understanding the role of ROS signalling in regulating metabolic activity, inflammatory activation, and cardiac diseases related to metabolic dysfunction. In this review, we summarize the current literature on REDOX and its role in the regulation of cardiac metabolism and inflammation, focusing on ROS, local REDOX signalling pathways, and other mechanisms.

scholarly journals GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective

2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Ramu Adela ◽  
Sanjay K. Banerjee
Keyword(s):  
Endothelial Cells ◽  
Cardiovascular Diseases ◽  
Clinical Decision Making ◽  
Tissue Injury ◽  
Kidney Diseases ◽  
Pathological Condition ◽  
Treatment Strategies ◽  
Growth Factor Receptor ◽  
Clinical Decision ◽  
Protective Role

Growth differentiation factor-15 (GDF-15) is a stress responsive cytokine. It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk. Increased GDF-15 levels are associated with cardiovascular diseases such as hypertrophy, heart failure, atherosclerosis, endothelial dysfunction, obesity, insulin resistance, diabetes, and chronic kidney diseases in diabetes. Increased GDF-15 level is linked with the progression and prognosis of the disease condition. Age, smoking, and environmental factors are other risk factors that may increase GDF-15 level. Most of the scientific studies reported that GDF-15 plays a protective role in different tissues. However, few reports show that the deficiency of GDF-15 is beneficial against vascular injury and inflammation. GDF-15 protects heart, adipose tissue, and endothelial cells by inhibiting JNK (c-Jun N-terminal kinase), Bad (Bcl-2-associated death promoter), and EGFR (epidermal growth factor receptor) and activating Smad, eNOS, PI3K, and AKT signaling pathways. The present review describes the different animal and clinical studies and patent updates of GDF-15 in diabetes and cardiovascular diseases. It is a challenge for the scientific community to use GDF-15 information for patient monitoring, clinical decision-making, and replacement of current treatment strategies for diabetic and cardiovascular diseases.

Sign in / Sign up

Export Citation Format

Share Document