scholarly journals Activating AhR alleviates cognitive deficits of Alzheimer's disease model mice by upregulating endogenous Aβ catabolic enzyme Neprilysin

Theranostics ◽  
2021 ◽  
Vol 11 (18) ◽  
pp. 8797-8812
Author(s):  
Cheng Qian ◽  
Chunjie Yang ◽  
Mengting Lu ◽  
Jiaxin Bao ◽  
Haiyan Shen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Catabolic Enzyme

scholarly journals A coimmunization vaccine of Aβ42 ameliorates cognitive deficits without brain inflammation in an Alzheimer’s disease model

2014 ◽  
Vol 6 (3) ◽  
pp. 26 ◽  
Author(s):  
Shuang Wang ◽  
Yang Yu ◽  
Shuang Geng ◽  
Dongmei Wang ◽  
Li Zhang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Brain Inflammation

scholarly journals Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

2019 ◽  
Vol 22 (5) ◽  
pp. 719-728 ◽  
Author(s):  
Peisu Zhang ◽  
Yuki Kishimoto ◽  
Ioannis Grammatikakis ◽  
Kamalvishnu Gottimukkala ◽  
Roy G. Cutler ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Progenitor Cell ◽  
Disease Model ◽  
Cell Senescence ◽  
Oligodendrocyte Progenitor Cell ◽  
Oligodendrocyte Progenitor

Transplantation of GABAergic Interneuron Progenitor Attenuates Cognitive Deficits of Alzheimer’s Disease Model Mice

2020 ◽  
Vol 75 (1) ◽  
pp. 245-260
Author(s):  
Mei-Hong Lu ◽  
Xiu-Yun Zhao ◽  
De-En Xu ◽  
Ji-Bo Chen ◽  
Wen-Li Ji ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Gabaergic Interneuron

Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer’s disease model

2014 ◽  
Vol 68 ◽  
pp. 126-136 ◽  
Author(s):  
Brice Ongali ◽  
Nektaria Nicolakakis ◽  
Xin-Kang Tong ◽  
Tahar Aboulkassim ◽  
Panayiota Papadopoulos ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Angiotensin Ii ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Receptor Blocker

Reduced expression of Na + /Ca 2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice

2018 ◽  
Vol 131 ◽  
pp. 291-303 ◽  
Author(s):  
Shigeki Moriguchi ◽  
Satomi Kita ◽  
Masahiro Fukaya ◽  
Makoto Osanai ◽  
Ryo Inagaki ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model

scholarly journals Use of Copper and Insulin-Resistance to Accelerate Cognitive Deficits and Synaptic Protein Loss in a Rat Aβ-Infusion Alzheimer's Disease Model

2008 ◽  
Vol 15 (4) ◽  
pp. 625-640 ◽  
Author(s):  
Aynun N. Begum ◽  
Fusheng Yang ◽  
Edmond Teng ◽  
Shuxin Hu ◽  
Mychica R. Jones ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Insulin Resistance ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Synaptic Protein ◽  
Protein Loss

scholarly journals Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools

2013 ◽  
Vol 125 (3) ◽  
pp. 465-472 ◽  
Author(s):  
Yasuyuki Mitani ◽  
Junko Yarimizu ◽  
Hiroki Akashiba ◽  
Yoshitsugu Shitaka ◽  
Keni Ni ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Selective Reduction

scholarly journals Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jiqing Xu ◽  
Fred de Winter ◽  
Catherine Farrokhi ◽  
Edward Rockenstein ◽  
Michael Mante ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Deficits ◽  
Disease Model ◽  
Neuregulin 1
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