scholarly journals Determinants of high blood pressure in children: a case-control study in a rural area of the Espírito Santo State / Determinantes da pressão arterial elevada em crianças: um estudo caso-controle em área rural do Espírito Santo

Author(s):  
Camila Brandão-Souza ◽  
Claudia Souza Dourado ◽  
Gabriela Callo Quinte ◽  
Gláucia Figueiredo Justo ◽  
Maria Del Carmen Bisi Molina

Objetivo: Identificar e analisar os fatores preditores da ocorrência da pressão arterial elevada em crianças de 7 a 10 anos de um município rural no Espírito Santo. Métodos: Foram constituídos dois grupos de estudo: os casos (PAS ou PAD ≥ P95) e os controles (PA <P90). Houve pareamento por sexo e idade. A amostra foi composta por sorteio sistemático e foram avaliadas 395 crianças, 79 casos e 316 controles. Resultados: A prevalência de excesso de peso nos casos foi de 8,9% e nos controles de 11,1%, o sedentarismo esteve presente em 88,1% dos casos e em 87,9% dos controles e a média do tempo de tela foi de 97,7 minutos e 106,6 minutos por dia nos casos e controles respectivamente. Conclusão: Observou-se a necessidade da criação de políticas públicas que visam promoção da saúde para que os grupos vulneráveis recebam assistência desde a infância. Descritores: Criança, Pressão alta, Hipertensão.

2016 ◽  
Vol 6 (3) ◽  
pp. 215
Author(s):  
Annibal Tagliaferri Sabino ◽  
Eduardo de Souza ◽  
Ana Lucia Goulart ◽  
Adriana Martins de Lima ◽  
Nelson Sass

2010 ◽  
Vol 5 (1) ◽  
pp. 122
Author(s):  
Elizabete Regina De Araújo Oliveira ◽  
Adriana Nunes Moraes ◽  
Carla Milena Coqueiro Secchin ◽  
Ana Paula Costa Velten ◽  
Maria José Gomes

ABSTRACTObjective: to analyze the relationship between lifestyle and other variables on hypertension. Method: this is about a case-control study performed with 120 users of the health unit of the district of Porto São Mateus/ES, matched the offer for one hypertensive of three normotensive. The instrument used was the profile of individual lifestyle as well as issues related to socio-economic profile. The project was approved by the Ethics Committee in Research of Centro Universitário Norte do Espírito Santo, of the Universidade Federal do Espírito Santo (043/2010). Results: there was a greater chance of developing hypertension with advancing age. The lifestyle was not statistically significant with hypertension, despite a greater exposure among normotensives. This fact can be attributed to a greater concern and health care by hypertensive only after the confirmation of the diagnosis of hypertension. Conclusion: adopting a healthy lifestyle from infancy to occur in order to prevent hypertension and not only serve as a treatment. Descriptors: life style; hipertensyon; risk factores.RESUMOObjetivo: analisar a relação do estilo de vida e de outras variáveis sobre a hipertensão arterial. Métodos: trata-se de um estudo de caso-controle realizado com 120 usuários da unidade de saúde do bairro Porto de São Mateus – ES, pareados na proporção de 3 hipertensos para 1 normotenso. O instrumento utilizado foi o Perfil do Estilo de Vida Individual além de questões relacionadas ao perfil sócio econômico. O projeto obteve aprovação do Comitê de Ética em Pesquisa do Centro Universitário Norte do Espírito Santo, da Universidade Federal do Espírito Santo, conforme parecer 043/2010. Resultados: observou-se maiores chances de desenvolver a hipertensão com o avanço da idade. O estilo de vida não apresentou significância estatística com a hipertensão arterial, apesar de uma maior exposição entre os normotensos. Tal fato pode ser atribuído a uma maior preocupação e cuidado com a saúde por parte dos hipertensos somente a partir da confirmação do diagnóstico de hipertensão. Conclusão: a adoção de um estilo de vida saudável deve ocorrer desde a infância a fim de se prevenir a hipertensão e não servir apenas como tratamento. Descritores: estilo de vida; hipertensão; fatores de risco.RESUMENObjetivo: analizar la relación entre el estilo de vida y otras variables en la hipertensión. Metodología: se trata de un estudio caso-control llevado a cabo con 120 usuarios de la unidad de salud del distrito de Porto São Mateus - ES,  en una proporción de 1 hipertensos a 3 normotensos. El instrumento utilizado fue el perfil de estilo de vida individual, así como cuestiones relacionadas con el perfil socio-económico. El proyecto fue aprobado por el Comité de Ética en Investigación del Centro Universitário Norte do Espírito Santo, de la Universidade Federal do Espírito Santo, con parecer 043/2010. Resultados: se observó una mayor probabilidad de desarrollar hipertensión con la edad avanzada. El estilo de vida no fue estadísticamente significativa con la hipertensión, a pesar de una mayor exposición entre los normotensos. Este hecho puede atribuirse a una mayor preocupación y la atención sanitaria hipertensos sólo después de la confirmación del diagnóstico de la hipertensión. Conclusión: la adopción de un estilo de vida saludable desde la infancia que se produzca con el fin de prevenir la hipertensión y no sólo servir como tratamiento. Descriptores: estilo de vida; hipertensión; factores de riesgo. 


Author(s):  
Luca Spiezia ◽  
Gianna Bogana ◽  
Elena Campello ◽  
Sara Maggiolo ◽  
Elena Pelizzaro ◽  
...  

AbstractPreeclampsia (PE) is a pregnancy complication characterized by high blood pressure and significant amounts of protein in the urine. Various coagulation abnormalities have been described in pregnant women with PE. The aim of the present case-control study was to evaluate whole blood thromboelastometry profiles, performed by ROTEMStandard ROTEMPreeclamptic women showed a significantly more rapid propagation phase in EXTEM assay than controls (CFT 62±15 vs. 75±15 s and α-angle 78±4 vs. 75±4°, p<0.01 in both cases). Moreover, MCF was significantly higher and ML significantly lower in women with PE than in healthy pregnant women (p=0.001 for all comparisons).ROTEM


2020 ◽  
Vol Volume 13 ◽  
pp. 425-430
Author(s):  
Mohammad Reza Namazi ◽  
Shekoofe Rouhani ◽  
Alireza Moarref ◽  
Mahsa Kiani ◽  
Seyed Sajjad Tabei ◽  
...  

Author(s):  
Annibal Sabino ◽  
Eduardo de Souza ◽  
Ana Goulart ◽  
Adriana Lima ◽  
Nelson Sass

Objective To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group. Methods A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used. Results In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age. Conclusion The presence of maternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well.


Author(s):  
Rajeev Gandham ◽  
CD Dayanand ◽  
SR Sheela

Introduction: Pre-eclampsia is a pregnancy specific disorder, characterised by the onset of hypertension and proteinuria. Pre-eclampsia is the leading cause of maternal, perinatal morbidity and mortality. The exact cause of pre-eclampsia is not known clearly and needs to be explored. Aim: To evaluate the maternal serum apelin 13 levels among pre-eclampsia and healthy pregnant women and also, to find the association between apelin 13 and blood pressure. Materials and Methods: A case-control study was conducted between Department of Biochemistry and Department of Obstetrics and Gynaecology, RL Jalappa Hospital and Research Centre, Kolar, Karnataka, India. After approval from the Institutional Ethics Committee and written informed consent from study subjects, a total of 270 pregnant women were recruited for this study. Among them, 135 pre-eclamptic women were considered as cases and 135 normotensive healthy pregnant women served as controls. According to the pre-eclampsia severity, cases were grouped into mild (n=47) and severe pre-eclampsia (n=88). Blood samples were collected from all the study subjects and was analysed for apelin 13 by Enzyme Linked Immunosorbent Assay (ELISA) method. Maternal and foetal adverse outcomes were recorded. Results were expressed as mean±Standard Deviation (SD). Categorical variables were expressed in percentages. Spearman’s correlation was applied and p<0.05 was considered significant. Results: The mean gestational age was 36.66±3.69 weeks which was, significantly low in pre-eclamptic women compared with healthy pregnant women. BMI (26.94±3.81 kg/m2), systolic (157.82±15.14 mmHg), diastolic (101.68±11.02 mmHg) and Mean Arterial Pressure (MAP) (120.20±11.12 mmHg), pulse rate (88.14±5.82 bpm), Aspartate Transaminase (AST) (25.25±12.49 IU/L) and Alanine Transaminase (ALT) (19.01±10.95 IU/L) were significantly increased in pre-eclamptic women when compared with control group. Mean maternal serum apelin 13 (341.44±218.63 pg/mL) concentrations were significantly lower in pre-eclampsia compared with healthy pregnant women. Maternal serum apelin 13 concentrations were negatively correlated with Systolic Blood Pressure (SBP) (r = -0.196), Diastolic Blood Pressure (DBP) (r = -0.172) and MAP (r =-0.204). Adverse maternal outcomes such as epigastric pain 75 (55.55%), oedema 62 (45.92%) and persistent headache 35 (25.92%) were higher in pre-eclamptic group. Additionally, adverse foetal outcomes were more in pre-eclamptic cases including significantly decreased birth weight (2.40±0.65), babies requiring Neonatal Intensive Care Unit (NICU) admission were 54 (40%), preterm birth (≤37 wks) in 50 (37.03%), Respiratory Distress Syndrome (RDS) 31 (22.96%), Small for Gestational Age (SGA) in 4 (2.96%) and Intra Uterine Death (IUD) in 11 (8.14%) babies. Conclusion: It was concluded from the present study that there was low maternal serum apelin 13 concentrations in pre-eclampsia and had negative correlation with blood pressure, suggesting its potential role in the pathophysiology of pre-eclampsia.


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