Thyroid diseases are divided into papillary carcinoma and nodular diseases, which are very harmful to the human body. Ultrasound is a common diagnostic method for thyroid diseases. In the process of diagnosis, doctors need to observe the characteristics of ultrasound images, combined with professional knowledge and clinical experience, to give the disease situation of patients. However, different doctors have different clinical experience and professional backgrounds, and the diagnosis results lack objectivity and consistency, so an intelligent diagnosis technology for thyroid diseases based on the ultrasound image is needed in clinic, which can give objective and reliable diagnosis opinions on thyroid diseases by extracting the texture, shape, and other information of the image and assist doctors in clinical diagnosis. This paper mainly studies the intelligent ultrasonic diagnosis of papillary thyroid cancer based on machine learning, compares the ultrasonic characteristics of PTMC diagnosed by using the new ultrasound technology (CEUS and UE), and summarizes the differential diagnosis effect and clinical application value of the two technology methods for PTMC. In this paper, machine learning, diffuse thyroid image features, and RBM learning methods are used to study the ultrasonic intelligent diagnosis of papillary thyroid cancer based on machine learning. At the same time, the new contrast-enhanced ultrasound (CEUS) technology and ultrasound elastography (UE) technology are used to obtain the experimental phenomena in the experiment of ultrasonic intelligent diagnosis of papillary thyroid cancer. The results showed that 90% of the cases were diagnosed by contrast-enhanced ultrasound and confirmed by postoperative pathology. CEUS and UE have reliable practical value in the diagnosis of PTMC, and the combined application of CEUS and UE can improve the sensitivity and accuracy of PTMC diagnosis.