An Oxidation Study of Phthalimide-Derived Hydroxylactams

A systematic study of the oxidation of 3-hydroxy-2-substituted isoindolin-1-ones (hydroxylactams) and their conversion to the corresponding phthalimides was undertaken using three oxidants. Of special interest was the introduction of nickel peroxide (NiO2) as an oxidation system for hydroxylactams and comparison of its performance with the commonly used pyridinium chlorochromate (PCC) and iodoxybenzoic acid (IBX) reagents. Using a range of hydroxylactams, optimal conversions of these substrates to the corresponding imides was achieved with 50 equivalents of freshly prepared NiO2 in refluxing toluene over 5–32 h reaction times. By comparison, oxidations of the same substrates using PCC/silica gel (three equivalents) and IBX (three equivalents) required oxidation times of 1–3 h for full conversion but required lengthier purification. While nominal amounts (~25 mg) of substrate hydroxylactams were used to ascertain conversion, scale-up procedures using all three methods gave good to excellent isolated yields of imides.

The Special Apparatus (al-Niẓām al-Khāṣṣ): The Rise of Nationalist Militancy in the Ranks of the Egyptian Muslim Brotherhood

Existing scholarship has largely focused on the role of Sayyid Qutb’s ideas when analyzing the Muslim Brotherhood’s violent history. Perceiving Qutb’s ideas as paving the way for radical interpretations of jihad, many studies linked the Brotherhood’s violent history with this key ideologue. Yet, in so doing, many studies overlooked the importance of the Special Apparatus in shaping this violent history of the Brotherhood, long before Qutb joined the organization. Through an in-depth study of memoires and accounts penned by Brotherhood members and leaders, and a systematic study of British and American intelligence sources, I attempt to shed light on this understudied formation of the Brotherhood, the Special Apparatus. This paper looks at the development of anti-colonial militancy in Egypt, particularly the part played by the Brotherhood until 1954. It contends that political violence, in the context of British colonization, antedated the Brotherhood’s foundation, and was in some instances considered as a legitimate and even distinguished duty among anti-colonial factions. The application of violence was on no account a part of the Brotherhood’s core strategy, but the organization, nevertheless, established an armed and secret wing tasked with the fulfillment of what a segment of its members perceived as the duty of anti-colonial jihad.

Antisite disorder and phase segregation in Mn2NiSn

A systematic study of crystal structure, local structure, magnetic and transport properties in quenched and temper annealed Ni2−xMn1+xSn alloys indicate the formation of Mn3Sn type structural defects caused by an antisite disorder between Mn and Sn occupying the Y and Z sublattices of X2YZ Heusler structure. The antisite disorder is caused by the substitution of Ni by Mn at the X sites. On temper annealing, these defects segregate and phase separate into L21 Heusler and D019 Mn3Sn type phases.

Systematic study of the (n,2n) reaction cross section for 121Sb and 123Sb isotopes

The cross sections of the 121Sb(n,2n) 120Sbm and 123Sb(n,2n) 122Sb reactions were measured at 12.50, 15.79 and 18.87 MeV neutron energies relative to the standard 27Al(n,α) 24Na monitor reaction using neutron activation and offline γ-ray spectrometry technique. Irradiations of the samples were performed at the BARC-TIFR Pelletron Linac Facility, Mumbai, India. The quasi-monoenergetic neutron was generated via the 7Li(p,n) reaction. Statistical model calculations were performed by nuclear reaction codes TALYS (ver. 1.9) and EMPIRE (ver. 3.2.2) using various input parameters and nuclear level density models. The cross sections of the ground and the isomeric state as well as the isomeric cross section ratio were studied theoretically from reaction threshold to 26 MeV energies. The effect of pre-equilibrium emission is also discussed in detail using different theoretical models. The present measured cross section were discussed and compared with reported experimental data and evaluation data of the JEFF-3.3, ENDF/B-VIII.0, JENDL/AD-2017 and TENDL-2019 libraries. A detailed analysis of the uncertainties in the measured cross section data was performed using the covariance analysis method. Furthermore, a systematic study of the (n,2n) reaction cross section for 121Sb and 123Sb isotopes were also performed within 14-15 MeV neutron energies using various systematic formulae. This work helps to overcome discrepancies in Sb data and illustrate a better understanding of pre-equilibrium emission in (n,2n) reaction channel.

The Advocacy Universe: A Methodology to Identify Politically Active 501(C)(4) Organizations

This article provides a framework that defines politically active 501(c)(4)s organizations and describes a methodology for identifying them among more than 80,000 social welfare organizations. We estimate that approximately 15% of (c)(4)s likely pursue advocacy or political action, while most are engaged in unrelated activities. Understanding the distinctive features of the social welfare sector and the politically engaged organizations within it are essential tasks for nonprofit scholars, yet the methodological and empirical challenges are complex and significant. To date, there has been no systematic study of the nature and efficacy of these organizations. We create a multistage methodology that allows researchers to identify politically active (c)(4)s and to investigate subgroups focused on different policy issues and with different member groups. This article summarizes how we identify organizations and strategies needed to reveal whether an organization is engaged in political activities. We explain the approach we took and the challenges we encountered.

The Transparency of Quantitative Empirical Legal Research (2018–2020)

Scientists are increasingly concerned with making their work easy to verify and build upon. Associated practices include sharing data, materials, and analytic scripts, and preregistering protocols. This has been referred to as a “credibility revolution”. The credibility of empirical legal research has been questioned in the past due to its distinctive peer review system and because the legal background of its researchers means that many often are not trained in study design or statistics. Still, there has been no systematic study of transparency and credibility-related characteristics of published empirical legal research. To fill this gap and provide an estimate of current practices that can be tracked as the field evolves, we assessed 300 empirical articles from highly ranked law journals including both faculty-edited journals and student-edited journals. We found high levels of article accessibility (86% could be accessed without a subscription, 95% CI = [82%, 90%]), especially among student-edited journals (100% accessibility). Few articles stated that a study’s data are available, (19%, 95% CI = [15%, 23%]), and only about half of those datasets are reportedly available without contacting the author. Preregistration (3%, 95% CI = [1%, 5%]) and availability of analytic scripts (6%, 95% = [4%, 9%]) were very uncommon. We suggest that empirical legal researchers and the journals that publish their work cultivate norms and practices to encourage research credibility.