Rich sulphide, cuprous and impregnated ores are currently mined in the underground mines of the Talnakh and Oktyabrskoye deposits at the depths from 250 to 1,700 m. The reserves of rich ores are depleted, and therefore the growth of cuprous and impregnated ores is gaining importance. Their share may reach 80% of the total production by 2030. A distinctive feature of such deposits is the occurrence of cuprous and impregnated ores above the rich sulphide ore, which reserves have been mined out using mining systems with curing backfill mixtures. In this context, mining of impregnated ores will be done in the undermined zones, which will lead to significant rock mass deformation, opening of existing natural and formation of new cracks, will affect the stability of mining structures and will require special measures to control rock pressure in the mines. The paper presents the results of assessing the stress-and-strain condition of the undermined mass of impregnated ores mined using the room-and-pillar cut-and-fill method at the depths of 500, 1000 and 2000 m. The assessment shows that no dangerous stress concentrations arise in the mining structures at great depths which creates preconditions for the safe development of such deposits. A significant increase in ore extraction will require upgrading of existing underground facilities. It is proposed to carry out pre-concentration of the mined ore in the underground conditions using modern crushing complexes, high-capacity mine separators to remove waste rock, which can subsequently be used as the backfill material. In this way, a closed-loop mining system is created that meets the efficiency requirements of mining production and integrated subsoil development.