ovarian metastases
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2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jacqueline Feinberg ◽  
Anjelica Hodgson ◽  
Nadeem R. Abu-Rustum ◽  
Kara Long Roche ◽  
Kay J. Park

2021 ◽  
Author(s):  
K Ben Hamida ◽  
I Zemni ◽  
N Boujelbene ◽  
A Mlouka ◽  
I Zidi ◽  
...  

Author(s):  
Richard van der Meer ◽  
Checca Bakkers ◽  
Elysa Rostamkhan ◽  
Ignace de Hingh ◽  
Rudi Roumen

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Chao Chen ◽  
Da Wang ◽  
Xiaoxu Ge ◽  
Jian Wang ◽  
Yuhuai Huang ◽  
...  

Abstract Purpose The aim of this study was to analyze prognostic factors for ovarian metastases (OM) in colorectal cancer (CRC) using data from a Chinese center. In addition, the study aimed at developing a new clinical scoring system for prognosis of OM of CRC patients after surgery. Patients and methods Data of CRC patients with OM were collected from a single Chinese institution (n = 67). Kaplan-Meier analysis was used to evaluate cumulative survival of patients. Factors associated with prognosis of overall survival (OS) were explored using Cox’s proportional hazard regression models. A scoring system to determine effectiveness of prognosis was developed. Results Median OS values for patients with or without surgery were 22 and 7 months, respectively. Size of OM, number of OM, peritoneal metastasis (PM), Peritoneal cancer index (PCI), and completeness of cytoreduction (CC) were associated with OS of patients through univariate analysis. Multivariate analysis using a Cox regression model showed that only CC was an independent predictor for OS. Three variables (the size of OM >15cm, PCI ≥ 10, and carcinoembryonic antigen (CEA) >30 ng/mL) assigned one point each were used to develop a risk score. The resulting score was used for prognosis of OS. Conclusion Surgical treatment of metastatic sites is effective and safe for CRC patients with OM. CC-0 is recommended for improved prognosis. The scoring system developed in this study is effective for prediction of OS of patients after surgery.


2021 ◽  
Vol 8 (1) ◽  
pp. 92-95
Author(s):  
Raouf Menoura ◽  
◽  
Rym Bouhraoua ◽  
Sofia Bicha ◽  
Fateh Hammoudi ◽  
...  

Krukenberg tumors (TK) define themselves as ovarian metastases from cancer more often digestive. These are rare tumors that represent 1 to 2% of ovarian tumors. They are characterized by the presence of “kitten ring” cells filled with mucus and a pseudo-sarcomatous proliferation of the ovarian stroma. Their evolution is quickly fatal. We report 1 case of Krukenberg tumor observed and operated on in June 2020 at the surgery Department B CHU Constantine. The symptoms began with a rectal syndrome with transient episodes of pelvic pain. In this regard, we will recall the epidemiological, clinical, and evolutionary characteristics of this disease. Keywords: Krukenberg tumor, rectal cancer, ovarian metastases, synchronous tumors, posterior pelvectomy.


2021 ◽  
pp. ijgc-2020-002328
Author(s):  
Lucas W Thornblade ◽  
Ernest Han ◽  
Yuman Fong

ObjectiveOvarian metastases occur in 3%–5% of patients with colorectal cancer. The role of oophorectomy in that setting continues to be debated. We aimed to assess the survival of women treated with metastasectomy for ovarian metastasis.MethodsRetrospective cohort study of patients in the California Cancer Registry (2000–2012) with stage IV colorectal cancer and ovarian metastases. Pathology other than adenocarcinoma was excluded. Adjusted Cox-proportional hazard analysis was applied to assess the risk of death.ResultsA total of 756 patients with synchronous ovarian metastases and 516 patients with metachronous ovarian metastases form the basis of this analysis. Median follow-up for the synchronous cohort was 21 months (IQR: 8–36). Median overall survival was 23 months (IQR: 10–42). Estimated 5-year survival reached 17% and 10-year survival was 8%. There was a significant difference in unadjusted survival between patients with solitary ovarian metastasis (median overall survival: 51 months) compared with those who had both ovarian and extraovarian metastases (20 months) (log-rank test, P<0.0001). For patients with solitary ovarian metastases, the 5- and 10-year survival was 46% and 31%, respectively. Among patients with synchronous ovarian metastases, longer unadjusted survival was observed after oophorectomy (median overall survival: 24 months) compared with no oophorectomy (18 months, log-rank P=0.01). For patients with metachronous diagnoses of colorectal cancer ovarian metastasis, the median disease-free survival was 19 months. The median survival after resection of metachronous ovarian metastases was 25 months, with the survival directly related to the disease-free interval until metastasis. For patients with resected metachronous ovarian metastases, the 5- and 10-year post-metastasectomy survival was 14% and 5%, respectively.ConclusionsPatients with colorectal cancer ovarian metastasis have favorable long-term survival. Survival rates are higher if the tumor is isolated to the ovary or if metachronous to the primary cancer.


2021 ◽  
Vol 50 (6) ◽  
pp. 102075 ◽  
Author(s):  
Dovile Cerkauskaite ◽  
Kastytis Zilinskas ◽  
Povilas Varnelis ◽  
Mohamad El Oreibi ◽  
Viktor Asejev ◽  
...  

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