The possibility of creating a setting agent containing collagen from the skin of a stingray (Bathyraja parmifera) is studied. The conditions of skin pretreatment (autoproteolysis), alkaline and hydrothermal treatment regimens are substantiated. Based on the study on protein content, including collagencontaining substances and viscosity, it was shown that the reasonable ratio for hydrothermal treatment is 1:1, temperature - 50 ° C, time - 2 hours.