Morphological traits of the development of the skin and wool cover in sheep of Prikatunsky meat and wool type

A large number of works are devoted to the development of the skin and hair cover of sheep, depending on their breed affiliation, age, feeding conditions and housing. The authors point out that along with other conditions the quality of wool and wool clip is greatly influenced by the conditions of the feeding of animals. A high level of feeding increases the wool clip and improves the quality of the wool and vice versa a low level reduces, causes thinning and worsens other physical properties of the wool. As is known, one of the significant factors that determine the increase in wool clip is the size of the animal and, consequently, the total area of the skin. The purpose of the research was to investigate the morphological traits of the development of the skin and wool cover in sheep of Prikatunsky meat and wool type. The research material was wool samples from four topographic areas of the animal’s body (side/thigh/back/belly) and skin (side) of different sex and age groups, selected from the animals of the studied groups. In the course of research, the quality of wool and indicators of the histostructure of the skin of Prikatunsky meat and wool type of sheep have been investigated. In terms of thick-haired of wool, replacement rams and gimbers of Prikatunsky meat and wool type of sheep were superior by 4,82 pcs. per mm² or 19,0 % and 4,41 pcs. per mm² or 15,8 % of adult animals, respectively. Balance secondary follicles/primary follicles in young animals were higher by 10,3 and 17,3 % compared to breeding rams and ewes. The wool of the replacement young animals was thinner by 7,28 and 4,78 microns and they were more thick-haired. The obtained data will be used in the mating campaign when mating program rams in order to improve the sheep of Prikatunsky meat and wool type.

Sex- and Age-Related Physiological Profiles for Brachial, Vertebral, Carotid, and Femoral Arteries Blood Flow Velocity Parameters During Growth and Aging (4–76 Years): Comparison With Clinical Cut-Off Levels

Ultrasound-derived blood flow velocity (BFV) levels [e.g., peak systolic velocity (PSV)], intrabeat indexes (e.g., resistive), and intersegment ratios [e.g., internal/common carotid artery (ICA/CCA) PSV ratio] are assessed to describe cardiovascular physiology and health status (e.g., disease severity evaluation and/or risk stratification). In this respect, fixed cut-off values (disregard of age or sex) have been proposed to define “significant” vascular disease from BFV-derived data (parameters). However, the use of single fixed cut-off values has limitations. Accurate use of BFV-derived parameters requires knowing their physiological age-related profiles and the expected values for a specific subject. To our knowledge, there are no studies that have characterized BFV profiles in large populations taking into account: (i) data from different age-stages (as a continuous) and transitions (childhood–adolescence–adulthood), (ii) complementary parameters, (iii) data from different arteries, and (iv) potential sex- and hemibody-related differences. Furthermore, (v) there is little information regarding normative data [reference intervals (RIs)] for BFV indexes.Aims: The aims of this study are the following: (a) to determine the need for age-, body side-, and sex-specific profiles for BFV levels and derived parameters (intrabeat indexes and intersegment ratios), and (b) to define RIs for BFV levels and parameters, obtained from CCA, ICA, external carotid, vertebral, femoral, and brachial arteries records.Methods: A total of 3,619 subjects (3–90 years) were included; 1,152 were healthy (without cardiovascular disease and atheroma plaques) and non-exposed to cardiovascular risk factors. BFV data were acquired. The agreement between left and right data was analyzed (Concordance correlation, Bland–Altman). Mean and SD equations and age-related profiles were obtained for BFV levels and parameters (regression methods; fractional polynomials).Results: Left and right body-side derived data were not always equivalent. The need for sex-specific RIs was dependent on the parameter and/or age considered. RIs were defined for each studied artery and parameter. Percentile curves were compared with recommended fixed cut-off points. The equations for sex, body-side, and age-specific BFV physiological profiles obtained in the large population (of children, adolescents, and adults) studied were included (spreadsheet formats), enabling to determine for a particular subject, the expected values and potential data deviations.

Repetition effects in action selection reflect effector- but not hemisphere-specific coding

Action choices are influenced by future and recent past action states. For example, when performing two actions in succession, response times (RT) to initiate the second action are reduced when the same hand is used. These findings suggest the existence of effector-specific processing for action selection. However, given that each hand is primarily controlled by the contralateral hemisphere, the RT benefit might actually reflect body side or hemisphere-specific rather than effector-specific repetition effects. Here, participants performed two consecutive movements, each with a hand or a foot, in one of two directions. Direction was specified in an egocentric reference frame (inward, outward) or in an allocentric reference frame (left, right). Successive actions were initiated faster when the same limb (e.g., left hand - left hand), but not when the other limb of the same body side (e.g., left foot - left hand) executed the second action. The same-limb advantage was evident even when the two movements involved different directions, whether specified egocentrically or allocentrically. Corroborating evidence from computational modeling lends support to the claim that repetition effects in action selection reflect persistent changes in baseline activity within neural populations that encode effector-specific action plans.

Ginseng in Hair Growth and Viability

The hair follicle is the unique organ that has the capacity of undergoing cyclic transformations following periods of growth (anagen), regression (catagen), and rest (telogen) regenerating itself to restart the cycle. The dynamic capacity of hair to growth and rest enables mammals to control hair growth and length in different body side and to change their coats. Unlike what is observed in many animals in which the pelage synchronously passes from one phase of the cycle to other all stages of growth cycle are simultaneously found in the human pelage, the growth pattern is a mosaic where the hair cycling staging of one hair root is completely independent of it nearest hair follicle, meaning that each follicular unit (FU) can contain follicles in different stages at any given time. A variety of factors, such as nutritional status, hormones, exposure to radiations, chemotherapy or radiotherapy, environmental pollution or drugs may affect hair growth, and affects the number of hairs, this progressive hair loss has a cosmetic and social impact that often significantly affects social and psychological well-being of the patient that suffers from this hair loss. Although a number of therapies, such as finasteride and minoxidil, are approved medications, a wide variety of classes of phytochemicals and natural products, including those present in ginseng are being testing. The purpose of this chapter is to focus on study the potential of ginseng and its metabolites in hair loss.

Wool productivity and marketable properties of sheepskins of the new domestic dual-purpose sheep breed – Russian meat merino

The results of a comprehensive assessment of the runes and morphological studies of the skin and wool coat of a new breed of Russian meat merino in comparison with domestic breeds Manych merino and Stavropol breed have been presented in the article. The detailed characteristics and description of the main properties of the coat and histological studies of the skin have been given. The results of the research have shown that stud rams and ewes of Russian meat merino breed have had an advantage over the domestic Manych merino and Stavropol sheep breeds in terms of wool clip and yield of pure wool, respectively, by 48,8; 79,4 and 3,6; 16,0 %, and 62,3–68,1 %. The fiber fineness on the body side of rams and ewes of Russian meat merino breed was in the range of 20,5 and 19,1 microns (70 q), while in rams and ewes of Manych merino and Stavropol breed these fluctuations were 20,7–21,8 microns (64 q). It should be noted that according to the 100-point scale of the comprehensive assessment of the rune all animals of Russian meat merino breed groups were rated “excellent” (more than 95 points). The study of the commercial properties of Russian meat merino sheepskins has shown the superiority in weight of paired sheepskins and their area over rams and ewes of Manych merino, respectively, by 24,3; 38,1 and 1,8; 5,8 %. Over the animals of Stavropol breed the superiority was 8,3; 9,8 and 3,8; 5,4 %. In terms of the thickness of the leather fabric, unprocessed sheepskins of Russian meat merino breed exceeded the indicators of rams and ewes of Manych merino by 26,7 and 19,3 %, and rams and ewes of Stavropol breed by 8,6 and 12,1 %, respectively. The ratio of the pilar layer of the skin to the reticular layer in Russian meat merino breed was less by 0,8-0,11 and 0,13-0,32 units, which indicates the superior strength of the skin tissue. The ratio of secondary hair follicles to primary ones is the most objective indicator of wool productivity. So, in animals of Russian meat merino breed this ratio is higher than in the Manych merino and Stavropol breed by 1,0 or 9,3 % and 1,2 or 11,3 % in rams, and 0,9 or 10,1 % and 1,7 or 20,9 % in ewes, respectively.

Kinematics of the motorcar body side deformation process during front-to-side vehicle collision and the emergence of a hazard to car occupants

The kinematics of the process of deformation of the motorcar body side in the culminating phase of a front-to-side vehicle collision has been examined as a possible basis for analyzing and modeling the process of emergence of a hazard to car occupants during a road accident. The course of such accidents has a complex nature and their models are necessarily based on the approximation of non-linear elastoplastic characteristics of impact processes, especially during the transition from the compression phase to the restitution phase of the deformation process. For such characteristics to be obtained, a lot of experimental tests have to be carried out. This paper addresses the short-duration processes with a high degree of complexity.A front-to-side motorcar collision model has been prepared, which made it possible to analyze the process of deformation of the car body side and the emergence of a hazard and injuries to car occupants. The results of calculation of the deformation rate and range in various car body zones, velocity of the test dummy placed on driver’s seat and velocity of possible dummy’s impact against the car body side being deformed may be taken as a basis for designing effective occupant protection systems. The kinematics of the phase of vehicle contact and deformation process was modeled with taking into account results of experimental tests, including the curves characterizing the largely non-linear processes that are decisive for the deformation of the car body side. The deformation processes analyzed on these grounds showed at the same time the range of penetration of the deformed body part into the car interior, which causes a hazard to vehicle occupants. The calculation results have shown e.g. that the car body side is deformed to a depth of 0.2 m as quickly as within 0.02–0.03 s. At such a car body side deformation range, the car body part being deformed hits occupant’s body in his/her hips and pelvis area with a velocity of about 6 m/s.

A detailed taxonomic study on two new and one known species of Anaplectus De Coninck & Schuurmans Stekhoven, 1933 (Nematoda: Plectidae)

This paper provides descriptions of two new and one known species of the genus Anaplectus De Coninck & Schuurmans Stekhoven, 1933. Anaplectus sudhausi sp. nov. is characterised by leaf-shaped lips interspersed with interlabial liplets; bifid apices of the lateral lips; cheilostom with non-cuticularised walls; gymnostom with cuticularised arcuate walls; 120–132 sublateral hypodermal glands on each body side with an additional 5–8 smaller subdorsal hypodermal glands; female tail with three caudal setae; males with arcuate spicules having manubrium slightly wider than calomus or blade, last median tubulus or supplement about half the spicule length and tail terminus with a weakly cuticularised spinneret. A. labiosulcus sp. nov. is characterised by 115–123 sublateral hypodermal glands on each side of the body with those on the dorsal side usually larger than the ventrals; the 5–6 anteriormost glands are unpaired and arranged linearly; lips with cuticularised interlabial grooves; gymnostom arched, occasionally double-arched and caudal glands grouped and opening through a cuticularised spinneret. A. granulosus (Bastian, 1865) De Coninck & Schuurmans Stekhoven, 1933 has been redescribed with some minor differences from previous descriptions.

Hemispheric Network Expression in Parkinson’s Disease: Relationship to Dopaminergic Asymmetries

Background: Parkinson’s disease (PD) is characterized by brain metabolic networks, specifically associated with motor and cognitive manifestations. Few studies have investigated network changes in cerebral hemispheres ipsilateral and contralateral to the clinically more affected body side. Objective: We examined hemispheric network abnormalities and their relationship to striatal dopaminergic deficits in PD patients at different stages. Methods: 45 PD patients underwent dual-tracer positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) and 18F-fluorodopa (FDOPA) in a high-resolution PET scanner. In all patients, we computed expression levels for the PD-related motor/cognition metabolic patterns (PDRP/PDCP) as well as putamen/caudate FDOPA uptake values in both hemispheres. Resulting hemispheric measures in the PD group were compared with corresponding healthy control values and assessed across disease stages. Results: Hemispheric PDRP and PDCP expression was significantly elevated contralateral and ipsilateral to the more affected body side in patients with unilateral symptoms (H&Y 1: p < 0.01) and in patients with bilateral limb involvement (H&Y 2-3: p < 0.001; H&Y 4: p < 0.003). Elevations in pattern expression were symmetrical at all disease stages. By contrast, FDOPA uptake in the caudate and putamen was reduced bilaterally (p < 0.002), with lower values on both sides at more advanced disease stages. Hemispheric uptake was asymmetrical in both striatal regions, with lower contralateral values at all disease stages. The magnitude of hemispheric uptake asymmetry was smaller with more advanced disease, reflecting greater change ipsilaterally. Conclusion: Symmetrical network expression in PD represents bilateral functional effects unrelated to nigrostriatal dopaminergic asymmetries.

Taxonomic revision of the Menticirrhus americanus (Linnaeus, 1758) and M. littoralis (Holbrook, 1847) (Percomorphacea: Sciaenidae) species complexes from the western Atlantic

The genus Menticirrhus is widely distributed in the Neotropical region, where its species are common and abundant in shallow coastal waters and estuaries. The diversity, biogeography, and evolutionary relationships of the Menticirrhus species are still poorly known, due primarily to the difficulty of differentiating the species, given the broad similarities in their external morphology. The present study is based on the analysis of morphological and molecular data, with the examination of type specimens and a comprehensive collection of non-type specimens from an ample geographic range. These analyses indicated that two widely distributed Western Atlantic species, Menticirrhus americanus and M. littoralis, represent species complexes. The M. littoralis species complex is characterized by the absence of dark bars on body side, and a smaller, light-colored pectoral fins, that barely reaching the tip of the depressed pelvic fins, with fewer pectoral-fin rays. This complex includes three species: M. littoralis, found in the Gulf of Mexico, M. gracilis, from the southeastern and southern coast of South America, and a new species, described here, from the northern to eastern Brazilian coast. The M. americanus species complex is characterized by the presence of dark bars on body side, and a large, dark pectoral fin, that surpass the tip of the depressed pelvic fin, with more pectoral-fin rays. This complex has two species, M. americanus, which occurs on the east coast of the United States and in the Gulf of Mexico, and M. martinicensis, found from Caribbean to Argentina, that represents a cryptic allopatric species. An identification key to all species of the genus is presented.