Drug Therapy and Adherence in Patients With Coronary Heart Disease: Results of the Russian Part of the EUROASPIRE V International Multicenter Study

Aim To study the practice of drug treatment of ischemic heart disease (IHD) and the consistency of this practice with the established guidelines.Material and methods Results of the Russian part of the EUROASPIRE V study were compared with the general European population of the study. At ≥6 mos. and <2 years after the discharge from the hospital, patients were invited to visit the site for an interview. The drug therapy recommended upon discharge and taken by patients in the long-term as well as the patients’ compliance with the treatment were analyzed. In Russian centers, 699 patients were registered, and 399 of them visited the centers for the interview.Results Upon discharge from the hospital, patients of the Russian cohort and of the entire study population were prescribed acetylsalicylic acid or other antiplatelet drugs (99.2% and 94.1%, respectively); beta-blockers (87.2 and 81.6%, respectively); angiotensin-converting enzyme (ACE) inhibitors (69.9% and 61.1%, respectively); sartans (16.5% and 14.2 %, respectively); calcium channel blockers (19.3 and 19.4 %, respectively); nitrates (8.0% and 22.5 %, respectively); diuretics (31.1 and 32.5 %, respectively); statins (98.0% and 85.0 %, respectively); and anticoagulants (6.6 and 8.3 %, respectively). For the long-term treatment, patients of the Russian cohort and of the entire study population took antiplatelets (94.7 % and 92.5 %, respectively); beta-blockers (83.2% and 81.0 %, respectively); ACE inhibitors (60.2% and 57.3 %, respectively); sartans (19.3% and 18.4 %, respectively); calcium antagonists (21.1% and 23.0 %, respectively); nitrates (9.0% and 18.2 %, respectively); diuretics (31.8% and 33.3 %, respectively); statins (88.2% and 80.8 %, respectively); and anticoagulants (8.8% and 8.2 %, respectively). High intensity hypolipidemic therapy was prescribed to 54.0 % of patients in Russian centers and 60.3 % of patients in the entire study. Both Russian and international patients evaluated their compliance with the prescribed medication as high.Conclusion According to results of the EUROASPIRE V study as compared to earlier studies, the practice of drug therapy in Russian patients with IHD has significantly approached European indexes. Further optimization is possible by a more extensive use of high intense hypolipidemic treatment and antidiabetic drugs with a documented positive effect on prognosis of cardiovascular diseases.

Major activities and provisional results of gold deposit forecasting in the eastern (Russian) part of Fennoscandian shield

The paper discusses the main gold metallogeny features within foreign Precambrian shields (excluding sedimentary-metamorphogene deposits of Au-rich conglomerates and magmatogene Au-rich Cu-Ni and PGE deposits) and regional features of the eastern Fennoscandian shield. Data on geological setting of Finnish gold deposits are summarized and analyzed. The paper briefly reviews gold prospecting knowledge within Karelian-Kola region and work results. The author compiled a digital model of gold-specific forecast-metallogenic map for the eastern Fennoscandian shield; based on this model, further prioritized exploration activities in Karelian-Kola region are proposed, potential for discovering medium-sized and major deposits of various formational and geological/economic types is forecasted.

Transboundary analysis of the land cover in Razdolnaya river basin

В статье рассмотрено пространственное распределение типов земель в пределах трансграничного бассейна р. Раздольная. На основе дешифрирования космических снимков Sentinel-2 и Landsat 8 составлена карта пространственного распределения типов земель по состоянию на 2019 г. Исходя из геоэкологической классификации ландшафтов В.А. Николаева в данной работе было выделено 12 типов земель: используемые и неиспользуемые сельскохозяйственные земли, используемые и неиспользуемые рисовые поля, карьеры, леса, лесопосадки, рубки, луга, застроенные земли, водные объекты, а также кустарники и редколесья. Представлены абсолютные и относительные площади для каждого типа земель по трансграничному бассейну в целом, а также отдельно для его российской и китайской частей. По результатам дешифрирования данных дистанционного зондирования установлено, что российская и китайская части бассейна р. Раздольная имеют существенные трансграничные различия в структуре земель. На российской части бассейна лесами покрыто чуть более половины площади, но при этом значительные площади занимают сельскохозяйственные земли и луга. В некоторых местах луга и сельскохозяйственные земли преобладают в большей степени, чем леса. На китайской части лесные территории доминируют над другими типами земель. Сельскохозяйственные земли и луга образуют узкие и длинные полосы и имеют более мозаичное распространение, чем на российской части. Здесь заметно меньше площади застроенных земель, а площади рубок и лесопосадок больше, чем на российской части. Площади карьеров примерно равны в обеих частях бассейна. The transboundary Razdolnaya river basin is nearly evenly split up between Primorsky Krai of Russian Federation and Heilongjiang and Jilin provinces of People’s Republic of China. The Chinese and the Russian parts of the transboundary river have developed independently of each other. Therefore, the two have a different land cover and land use structure. The analysis of land cover and land use structure is of utmost importance for the understanding the modern state of land development and the possibilities of its future development. Using the remote sensing data, such as Sentinel-2 and Landsat 8 satellite imagery, the land cover and land use map of the Razdolnaya transboundary river basin for 2019 has been composed by means of the ArcMap 10.5 software package. According to V.A. Nikolaev’s geoecological classification of landscapes, we have identified 12 land types: forests, meadows, shrubs and woodlands, agricultural lands, unused agricultural lands, rice fields, unused rice fields, built-up areas, reforestation lands, logging, quarries, and bodies of water. We have provided area coverage for each type of land of the whole transboundary basin, and for the Russian and Chinese parts. According to the results of computer-aided visual deciphering and automatic deciphering, forests are the most common land use type in the basin. In the Chinese part of the basin, forests dominate over the other types of land. Agricultural lands and meadows have assumed narrow and linear shapes. Built-up areas have less coverage here than in the Russian part of the basin. However, the coverage of logging and reforestation lands is considerably larger than in the Russian part of the basin. In the Russian part of the basin, forests co-dominate with the agricultural lands and meadows. In some areas of this part of the basin forests disappear almost completely. The Russian part of the basin also has the larger coverage of shrubs and woodlands, unused agricultural lands, rice fields and unused rice fields. The coverage of quarries is roughly equal in both parts of the basin.

MINERALIZATION OF SMALL RIVERS WATER IN THE AMUR REGION

The authors have considered mineralization of small rivers water in the Russian part of the Amur basin. The lowest values are observed in water of the rivers, draining intrusions; the highest ones – in the rivers of the areas with ore occurrences and deposits of polymetals, karst development and mineral water outlets. The maximum salinity is characteristic of the river waters in the urbanized territories.

Из наблюдений над семантикой имперфективного будущего в среднерусской письменности

The present paper investigates differences between the semantic types of predicates which occurred in the constructions with the auxiliaries budu and stanu in Middle Russian. The data for the research was collected using the Middle Russian part of the Russian National Corpus. The examples in the final dataset were classi fied according to the date, source, and semantic type of the verb used in the constructions in question. The study has shown that states were more likely to co-occur with the auxiliary budu, whereas accomplishments denoting the accumulation of effect — with the auxiliary stanu. Such differences between budu and stanu show that budu was not a simple “foreign” replacement for stanu but penetrated the verb system through a separate set of contexts not related to expressing inchoative meaning.