News from the Cold Chamber: Clinical Experiences of POLARx versus Arctic Front Advance for Single-Shot Pulmonary Vein Isolation

Cryoballoon (CB)-guided pulmonary vein isolation (PVI) represents a cornerstone in the treatment of atrial fibrillation (AF). Recently, a novel balloon-guided single shot device (POLARx, Boston Scientific) was designed. Our study aimed to compare the efficacy, safety and characteristics of the novel CB system with the established one (Arctic Front Advance (Pro), AFA, Medtronic). A total number of 596 patients undergoing CB-guided ablation for AF were included. 65 patients (65.0 ± 11.6, 31% female) undergoing PVI with the POLARx were compared to a cohort of 531 consecutive patients (63.0 ± 27.9, 25% female) treated with AFA. Acute PVI was achieved in all patients (n = 596, 100%). Total procedure duration (POLARx 113.3 ± 23.2 min, AFA 100.9 ± 21.3 min; p < 0.001) and fluoroscopy time (POLARx 10.5 ± 5.9 min, AFA 4.8 ± 3.6 min; p < 0.001) were significantly longer in the POLARx group. The POLARx balloon achieved significantly lower nadir temperatures (POLARx −57.7 ± 0.9 °C, AFA −45.1 ± 2.6 °C; p < 0.001) and a significantly higher percentage of pulmonary veins successfully isolated with the first freeze (p = 0.027 *). One major complication occurred in the POLARx (2%) and three (1%) in the AFA group. Both ablation systems are comparably safe and effective. AF ablation utilizing the POLARx system is associated with longer procedure and fluoroscopy times as well as lower nadir temperatures.

Post-mortem characterization of Dorper x Santa Inês lambs fed diets containing alternative foods

The objective of this study was to evaluate the post-mortem characteristics of lambs fed diets containing alternative foods. Twenty lambs, castrated Dorper x Santa Inês males, aged approximately 90 days and with mean weight of 20 kg were used. Experimental diets were composed of ground corn, soybean meal, mineral supplement, urea and Tifton-85 hay (forage). In addition to these ingredients, cottonseed, sunflower meal and castor bean cake were used as alternative foods in the proportions of 10, 8 and 8% of %DM, respectively. The experiment lasted 106 days, with 14 days for adaptation and 92 days for evaluation and data collection. At the end of the confinement period, the lambs were slaughtered, and the carcasses kept under cooling for a period of 24 hours. The measurements of pH, carcass temperature (internal and external) were measured in the Longissimus lumborum muscle, as well as the temperature and relative humidity of the cold chamber were measured. Muscle pH was altered as a function of diet and reached a value of 5.78 (lower pH) when lambs received the diet with castor bean cake. The internal carcass temperature was higher in the lambs that received the diet containing cottonseed (19.98°C), sunflower meal (19.71°C) and castor bean cake (19.87°C). The alternative foods can be used as ingredients in the formulation of diets for Dorper x Santa Inês lamb, for promoting the proper development of the post-mortem process, characteristic of good quality sheep meat.

Physiological Quality of Swingle Citrumelo Seed after Refrigerated Storage of Fruits and Seeds

For citrus, there is no definition of the ideal fruit harvesting point for seed extraction. Some studies have shown the positive effect of postharvest refrigerated storage of fruits to obtain quality seeds. This study aimed to evaluate the influence of the fruit maturation stage on the germination of Swingle citrumelo (CS) seeds after the refrigerated storage of fruits and seeds. CS fruits were harvested at 180 days after anthesis (DAA); 210 DAA and 240 DAA. Fruits and seeds were stored in cold chamber for 0, 15, 30, and 45 days. Physicochemical analyses were performed on fruits (colour, soluble solids, acidity and ratio) and seeds (water content, germination, and emergence). Germination of seeds extracted from fruits harvested at 180, 210, and 240 DAA, without refrigerated storage, showed a positive correlation with colour index. The refrigerated storage of fruits and seeds extracted from fruits harvested at 210 DAA, increased the seed germination rate. Peel colour (IC) was correlated positively with the germination of Swingle citrumelo seeds. The results of this study revealed that the absence of refrigerated storage, harvesting Swingle citrumelo fruits, with ripe characteristics (end of harvest), results in a high seed germination rate. On the other hand, refrigerated storage of fruits and seeds extracted from fruits harvested at mid-harvest increases the seed germination rate.

Effect of vacuum system on porous product defects and micro structures on the ADC-12 aluminum material with cold chamber die casting machines

Research on the effect of the vacuum system on porous product defects and microstructure on the ADC-12 aluminum alloy material with cold chamber die casting machine has been carried out. In the injection process in cold chamber die casting, the aluminum material commonly used is namely ADC-12. The ADC-12 aluminum alloy has better resistance to corrosion, is lightweight, has ease of casting, good mechanical properties, and dimensional stability. The purpose of this study is to compare the vacuum system with overflow system using ADC-12 aluminum alloy material with observed parameters are porosity, trapped air pressure, hot spot level, hardness level of Vickers Hardness, XRD analysis, and microstructure analysis with Light Optical Microscope (LOM). The results of the analysis using the Magma flow software, the vacuum system is better than the overflow system in terms of porosity and product yield, which is influenced by the amount of air trapped and the hot spot level. The level of hardness in a product with a vacuum system is better than a product with an overflow system. The average hardness in the vacuum system is 162,235 while in the overflow system is 147,615. Thus, the use of a vacuum system can increase the level of hardness in products by around 9%. With the change in usage from the overflow system to the vacuum system, it shows an increase in dislocation density followed by an increase in lattice strain and a decrease in the level of crystal size of the product.

Performance of Calcium Chloride- Ammonia Adsorption Refrigeration System

An experimental study on the performance of calcium chloride-ammonia adsorption system is described. A single bed water cooled condenser adsorption refrigerator prototype, which utilises calcium chloride-ammonia pair has been developed and tested in the laboratory. Experiments have been conducted for desorption temperatures of 100 °C with desorption time varying from 1 to 4 hours. An electric tape heater and a timer were used to perform the experiments. The adsorption temperature profile, adsorption rate and prototype performance have been analysed and discussed. The tested heating and desorption temperature of 100 °C and heating and desorption time of 1 to 4 hours was able to create a cooling effect of the cold chamber of the prototype of between -0.8 to 8.3 °C, which is adequate for vaccine storage requirement of 2 to 8 °C. The estimated Coefficient of Performance of the system ranges between 0.025 and 0. 076.

Thermal Characterization of Different Insulating Materials via Experimental Analysis in a Guarded Hot Box

The thermal characterization of building envelope materials is a crucial phase in understanding the building energy performance, and it is commonly evaluated through the thermal transmittance, often synthetically indicated as U-value. There are several ways to experimentally assess the U-value of insulating materials and multi-layers systems, usually defined by means of experimental in-situ heat flux measurements, where, however, a considerable variation of the boundary conditions may occur, making the measurement difficult. In this work, the experimental thermal characterization of different insulating materials applied to an X-lam wall is presented. The analysis is carried out using a Guarded Hot Box, which allowed to reproduce real, repeatable, and controlled operating conditions. Two different insulating materials were selected: expanded polystyrene (EPS) with graphite and hemp. The experimental tests were carried out by imposing a temperature difference reproducing the common operating conditions (0°C in cold chamber and 20°C in hot chamber). Steady-state conditions (constant temperature in the chambers) have been imposed to determine the thermal properties of the multi-layer systems. The tests, lasted 72 hours each, showed U-values equal to 0.15 W/m2K ± 3.1% for EPS with graphite and 0.19 W/m2K ± 3.1% for hemp.

Waste assessment in distribution and marketing logistics of horticultural products: evidence from Brazil

Worldwide, one-third of the food produced is inconsumable due to marketable quality losses. Parallelly, and given the growing world population, levels of waste have become unacceptable. Supply channels play a fundamental role in establishing strategies for food waste mitigation. The objective of this research was to analyze if good operational practices with different dimensions of distribution and commercialization logistics may contribute to reduce fruit and vegetable waste. The studied dimensions were: logistics, operations, technology, trade and management. Several questionnaires were administered to 83 specialized wholesale merchants from a large supply center in Brazil, for lettuce, potato, orange, papaya and tomato. The results indicated that for papaya and potato, low and high waste generation are associated with a greater number of anti-waste actions (p = 0.0071 and p = 0.0469 respectively). For tomato, lettuce and orange, no significant differences for found. These results represent a first approach to understanding the reasons for food waste at wholesale centers. Highlights: Worldwide, one-third of the food produced is inconsumable due to marketable quality losses. In Brazil, about 40 thousand tons of food is wasted per year. Food waste in the fruit and vegetable supply chain is associated with the following dimensions: logistics, operation, technology, trade and management. For papaya and potatoes, low levels of residues are associated with a greater number of anti-waste actions such use of a cold chamber and use of promotional pricing, respectively. For tomato, lettuce and orange, no significant differences was found for high and low levels of waste in relation to the number of actions undertaken in these chains.