A pre experimental study to assess the effectiveness of planned teaching program regarding respiratory care of intubated patients in terms of knowledge and practice among the ICU staff nurses working in selected hospital at Delhi, NCR, The objective of the study was to assess the effectiveness of Plan Teaching Programme (PTP) on knowledge and practice regarding the respiratory care of intubated patient among ICU staff nurses. This study was conducted on 30 staff nurses of Lady Harding medical college and hospital Delhi NCR. Pre- experimental research design was adopted and purposive sampling technique was used to select the sample. A structured knowledge questionnaire of 25 questions and practice checklist of 30 items were prepared to assess the knowledge and practice of the staff nurses. Data obtained were analyzed and interpreted by using both descriptive and inferential statistics in terms of frequency, percentages, Mean, S.D and Co-relation. Findings showed that In Pre-test Majority of Staff Nurses i.e. 19 (63%) were having V. good knowledge respectively. Whereas in Post Test 17 (57%) were having excellent knowledge regarding care of intubated patient in ICU which indicates an increase in knowledge score. In Pre-test Majority of Staff Nurses i.e. 19 (63%) were having V. good knowledge respectively. Whereas in Post Test 17 (57%) were having excellent knowledge regarding care of intubated patient in ICU which indicates an increase in knowledge score. The mean Post test practice check list score of Staff Nurses is (21.63) which is higher than the mean Pre test practice check list (14.23), with the mean difference of 7.4. The obtained mean difference was found to be statistically significant. The calculated t value is 23.81 which is greater than the table value at 0.05 level of significance at df (29).The findings revealed that the coefficient of correlation between post test knowledge score and post test practice score regarding respiratory care of intubated patient in ICU among staff nurses is 0.94 which is statistically significant.