Аpplication of nifuratel in treatment of cystitis in women

Cystitis is the most common pathology of the urinary tract in women both in our country and abroad. The high incidence of this disease in women in the population is influenced by anatomical, physiological features of the female body, violations of personal and sexual hygiene, burdened with an obstetric and gynecological (OAG) history, etc. In the current domestic and foreign recommendations for the diagnosis and treatment of cystitis in women, it is noted that in the vast majority of cases (up to 80% cases), the causative agent of cystitis is Escherichia coli, sensitive to nitrоfuran drugs.The purpose of the work. To demonstrate the effectiveness of the use of nifuratel (Nifuratel-SZ, Northern Star Co., Russia) in women with cystitis of various age groups using clinical examples. In the first clinical example, the high effectiveness of the use of nitrоfuran was shown in a woman of active reproductive age with OAG, in the second, in a teenager with an acute inflammatory process, in the 3rd-in a postmenopausal patient with concomitant multiple organ pathology.Conclusion. Nifuratel (Nifuratel-SZ, Northern Star Co., Russia) has proven to be a highly effective and safe drug with a wide range of antibacterial effects in patients with cystitis of different age groups.

Liquid Labyrinths

Stewart Parker’s play, Northern Star, begins with the character of Henry Joy McCracken reciting his seaborn heritage as a descendant of Huguenots and Covenanters, his mongrel inheritance ‘natural’ to his Belfast birth, the city a port of refuge from ‘the storm of history’. McCracken is remembered now as a United Irishman who was executed for his part in the 1798 rebellion, an insurrection that lingers still in the public consciousness of the city and its past. Northern Star was first performed in 1984 and through it Parker created a space for expressions of identity and place beyond the Troubles; that he did so in metaphors of storms and sea suggests the imaginative depth of the city’s maritime attachments, which form the basis of this chapter’s readings of mid-twentieth-century cultural production in the north of Ireland, including Seamus Deane, Medbh McGuckian, Sinead Morrissey, Glenn Patterson, and Ciaran Carson.

Effectiveness and safety of Tadalafil-SZ (NJSC “Northern Star”) at 5 mg / day in patients with symptoms of voiding dysfunction due to prostatic hyperplasia

The study objective is to evaluate effectiveness and safety of Tadalafil-SZ (NJSC “Northern Star”) at 5 mg / day in treatment of patients with symptoms of voiding dysfunction due to prostatic hyperplasia.Materials and methods. The study was conducted at the “Family Polyclinic No. 4” between January and June of 2019 and included 74 patients. Effectiveness was evaluated using the International Prostatic Symptom Score, International Index of Erectile Function, maximum urine flow rate and transrectal ultrasound examination.Results. After 3 months of therapy with tadalafil, positive dynamics of all characteristics were observed. Symptom severity prior to treatment was 11.50 ± 0.27 points, after treatment it was 10.00 ± 0.31 points. Maximum urine flow rate prior to treatment was 10.80 ± 0.20 ml / s, after treatment it was 11.10 ± 0.19 ml / s. The International Index of Erectile Function increased from 16.60 ± 0.30 prior to treatment to 20.20 ± 0.24 after treatment. Prostate volume before treatment was 43.70 ± 0.87 cm3, after treatment it was 40.30 ± 0.72 cm3.Conclusion. Tadalafil at 5 mg / day significantly decreases symptoms of voiding dysfunction and prostate volume, improves erectile function.