Identification of Diabetic Retinopathy through Machine Learning

A cross-sectional study of patients with suspected diabetic retinopathy (DR) who had an ophthalmological examination and a retinal scan is the focus of this research. Specialized retinal images were analyzed and classified using OPF and RBM models (restricted Boltzmann machines). Classification of retinographs was based on the presence or absence of disease-related retinopathy (DR). The RBM and OPF models extracted 500 and 1000 characteristics from the images for disease classification after the system training phase for the recognition of retinopathy and normality patterns. There were a total of fifteen different experiment series, each with a repetition rate of 30 cycles. The study included 73 diabetics (a total of 122 eyes), with 50.7% of them being men and 49.3% being women. The population was on the older side, at 59.7 years old on average. The RBM-1000 had the highest overall diagnostic accuracy (89.47) of any of the devices evaluated. The RBM-500 had a better autodetection system for DR signals in fundus images than the competition (100% sensitivity). In terms of specificity, RBM-1000 and OPF-1000 correctly identified all of the images that lacked DR signs. In particular, the RBM model of machine learning automatic disease detection performed well in terms of diagnostic accuracy, sensitivity, and application in diabetic retinopathy screening.

An online diabetic retinopathy screening tool for patients with type 2 diabetes

AIM: To develop a useful diabetic retinopathy (DR) screening tool for patients with type 2 diabetes mellitus (T2DM). METHODS: A DR prediction model based on the Logistic regression algorithm was established on the development dataset containing 778 samples (randomly assigned to the training dataset and the internal validation dataset at a ratio of 7:3). The generalization capability of the model was assessed using an external validation dataset containing 128 samples. The DR risk calculator was developed through WeChat Developer Tools using JavaScript, which was embedded in the WeChat Mini Program. RESULTS: The model revealed risk factors (duration of diabetes, diabetic nephropathy, and creatinine level) and protective factors (annual DR screening and hyperlipidemia) for DR. In the internal and external validation, the recall ratios of the model were 0.92 and 0.89, respectively, and the area under the curve values were 0.82 and 0.70, respectively. CONCLUSION: The DR screening tool integrates education, risk prediction, and medical advice function, which could help clinicians in conducting DR risk assessments and providing recommendations for ophthalmic referral to increase the DR screening rate among patients with T2DM.