Staphylococcus aureus—A Known Opponent against Host Defense Mechanisms and Vaccine Development—Do We Still Have a Chance to Win?

The main purpose of this review is to present justification for the urgent need to implement specific prophylaxis of invasive Staphylococcus aureus infections. We emphasize the difficulties in achieving this goal due to numerous S. aureus virulence factors important for the process of infection and the remarkable ability of these bacteria to avoid host defense mechanisms. We precede these considerations with a brief overview of the global necessitiy to intensify the use of vaccines against other pathogens as well, particularly in light of an impasse in antibiotic therapy. Finally, we point out global trends in research into modern technologies used in the field of molecular microbiology to develop new vaccines. We focus on the vaccines designed to fight the infections caused by S. aureus, which are often resistant to the majority of available therapeutic options.

Perceptions of non-native speakers of Arabic language towards cloud-based educational activities based on the entrance of multiple intelligences.

The need to diversify educational cloud activities arose due to social distancing, the widening of individual differences between learners, and the need to employ the possibilities offered by cloud education to achieve language goals. This research identifies the perceptions of non-native Arabic language learners towards the cloud-based educational activities based on the entrance of multiple intelligences. The descriptive approach was used, and a questionnaire was designed, consisting of: (Linguistic, Musical, visual- Spatial, Interpersonal, and Interpersonal). The sample consisted of (33) male and female students. The results showed that learners' perceptions are highly positive on all areas of activities. The highest percentage was interpersonal intelligence activities. Also, there are no statistically significant differences due to the sex. The originality of the research presents a vision of the entrance of multiple intelligences; To benefit from its educational applications in teaching Arabic online to non-native speakers, and to keep pace with global trends in the adoption of cloud education and its activities. It is also expected that the results of this research will benefit the following groups: institutions concerned with teaching foreign languages, experts who prepare curricula for teaching Arabic, and teachers of Arabic for non-native speakers.

Global Trends in Urban Agriculture Research: A Pathway toward Urban Resilience and Sustainability

Urban agriculture has been proposed as an important urban element to deal with the challenges of food insecurity and environmental deterioration. In order to track current popular topics and global research trends in urban agriculture, we used bibliometric analysis and visualization mapping to evaluate and analyze the developments in the knowledge of urban agriculture based on 605 papers from the core collection database Web of Science from 2001–2021. The results were as follows. (1) The number of urban agriculture publications increased substantially year by year, indicating that the field is attracting increasing attention. The University of Kassel, Chinese Academy of Sciences, and University of Freiburg are the most productive research institutions in the field of urban agriculture. The top-five most influential countries are the Unites States, Germany, the United Kingdom, Italy, and China, of which the Unites States plays a central role in the cooperative linkage between countries. (2) Research on urban agriculture focuses not only on food production and different styles but also on how to realize the various functions of urban agriculture. In addition, UA-related sustainability and the water-energy-food nexus have become two emerging research topics. (3) Urban agriculture does not necessarily mean a resource-conserving and environmentally friendly food system. To achieve sustainable development, a transition based on technological innovation is needed. How to improve the sustainable development level of the food system while fully considering the resilience, sustainability, and versatility of urban agriculture is the main direction of future research.

The Influence of Composition and Recipe Dosage on the Strength Characteristics of New Geopolymer Concrete with the Use of Stone Flour

Currently, considering global trends and challenges, as well as the UN sustainable development goals and the ESG plan, the development of geopolymer binders for the production of geopolymer concrete has become an urgent area of construction science. This study aimed to reveal the influence of the component composition and recipe dosage on the characteristics of fine-grained geopolymer concrete with the use of stone flour. Eleven compositions of geopolymer fine-grained concrete were made from which samples of the mixture were obtained for testing at the beginning and end of setting and models in the form of beams and cubes for testing the compressive strength tensile strength in bending. It was found that the considered types of stone flour can be successfully used as an additive in the manufacture of geopolymer concrete. An analysis of the setting time measurements showed that stone flour could accelerate the hardening of the geopolymer composite. It was found that the addition of stone waste significantly improves the compressive strength of geopolymers in comparison with a geopolymer composite containing only quartz sand. The maximum compressive strength of 52.2 MPa and the tensile strength in bending of 6.7 MPa provide the introduction of potassium feldspar in an amount of 15% of the binder mass. Microstructural analysis of the geopolymer composite was carried out, confirming the effectiveness of the recipe techniques implemented in this study.

Critical analysis of factors determining sustainable development of territories in a strategic perspective

The main interpretations of terms, development trends, foreign and domestic experience within the concept of sustainable development of territories have been considered. The importance of cooperative interaction and cooperation between actors in the same area in the context of existing constraints, barriers and opportunities for the deployment of the processes under consideration, has been confirmed. A statistical comparative analysis of the dynamics of changing trends in the interaction between research organisations and industrial enterprises of the regions has been carried out in comparison with Russian and global trends. The interrelationships between the key factors relating to financial support processes, infrastructure capacity and the research and education component have been revealed and their impact on territorial development has been highlighted. Scientific research methods such as analysis and generalization and correlation analysis were used within the framework of the article.

Terrorist Attacks in Western Europe: A Counter-Terrorism Medicine Analysis

Background: The modern concept of terrorism has its roots in the “old continent” of Western Europe, more specifically in France, during the “Reign of Terror” period of the French Revolution. At the time, this form of state terror had a positive connotation: it was a legitimate means of defending the young state. While no single accepted definition of terrorism exists today, it is universally considered an attack on both state and society. The health care impacts of terrorist attacks often extend disproportionally beyond the casualty toll, but the potential for such events to induce mass casualties remains a concern to Disaster Medicine and Counter-Terrorism Medicine (CTM) specialists. Method: Data collection was performed using a retrospective database search through the Global Terrorism Database (GTD). The GTD was searched using the internal database search functions for all events which occurred in Western Europe from January 1, 1970 - December 31, 2019. Years 2020 and 2021 were not yet available at the time of the study. Primary weapon type, country where the incident occurred, and number of deaths and injured were collated. Results were exported into an Excel spreadsheet (Microsoft Corp.; Redmond, Washington USA) for analysis. Results: A total of 15,306 events were recorded in Western Europe out of a total of 201,183 events world-wide between the years 1970 and 2019 inclusive. This resulted in a total of 5,548 deaths and 17,187 injuries. Explosives were used as a primary weapon/attack modality in 8,103 attacks, followed by incendiary attacks in 3,050 events and firearm use in 2,955 events. The use of chemical, biological, radiation, and nuclear (CBRN) weapons was rare and only accounted for 47 events. Conclusion: From 1970 through 2019, 9.11% of all terrorist attacks occurred in Western Europe. Compared to global trends of attack methodologies in the same study period, the use of explosives as a primary attack modality in Western Europe was similar (52.94% in Western Europe versus 48.78% Global). Firearm use was comparatively low (19.31% versus 26.77%) and the use of CBRN as an attack modality was rare (0.30% versus 0.20%). The United Kingdom, Spain, and France accounted for over 65% of all terrorist attacks and over 75% of terrorism-related deaths in Western Europe.