Encoding multiple digital DNA signals in a single analog channel

For many analytic and biomedical applications, the presence of an analyte above or below a critical concentration is more informative for decision making than the actual concentration value. Straightforward analog-to-digital signal conversion does not take full advantage of the precision and dynamic range of modern sensors. Here, we present and experimentally demonstrate an analog-to-multiple-digital signal conversion, reporting digital signals that indicate whether the concentrations of specific DNA sequences exceed respective threshold values. These threshold values can be individually programmed for each target sequence. Experimentally, we showed representation of four DNA targets’ information in a single fluorescence channel.

RADAR TARGET IMITATOR

The paper describes a single channel imitator for radar signals which was designed and made practically to generate a signal reflected from an aerial target with a given trajectory on the intermediate frequency band. Presented setup can be used to verify the analog channel for radar signal processing at intermediate frequencies and the DSP algorithms used to estimate coordinates of the imitated target.

Digital Estimation and Compensation of Analog Errors in Frequency-Interleaved ADCs

A novel digital compensation scheme for measuring, estimating and correcting linear weakly time-varying analog errors in frequency-interleaved analog-to-digital converters (FI-ADCs) is presented. This method features three important improvements over existing approaches: First, the Wigner–Ville distribution (WVD) is used to better estimate the nonstationary analog channel frequency response (ACFR) spectrum. Secondly, the estimated ACFR spectrum is approximated with a rational polynomial model using the [Formula: see text]-norm metric. The corresponding [Formula: see text]-norm minimization problem is solved using a primal-relaxed dual global optimization (PRD-GOP) method. Thirdly, the digital compensation circuitry is designed utilizing a preconditioned biconjugate gradient stabilized (BICGSTAB) algorithm that yields a computationally efficient solution. Numerical experimentations have been conducted and the outcomes validate the feasibility and superior performance of this proposed method.