This paper presents a comparison between different types of propellers operated in calm water to evaluate their performance behind hulls and in open-water conditions. A bulk carrier is chosen as a case study to perform the simulation and to evaluate the performance of several propeller series, namely the Wagengein B-series, Kaplan 19A, and MAU. Firstly, optimization procedures are performed by coupling a propeller design tool and a nonlinear optimizer to find the optimum design parameters of a fixed-pitch propeller. This optimization model aims to design the propeller behind the hull at the engine operating point with minimum fuel consumption and maximum propeller efficiency. The two main objectives of this study and the constraints are defined in a single fitness function to find the optimum values of the propeller geometry and the gearbox ratio. By considering the benefits of the single-objective over the multi-objective optimization problem, this model helps to find the optimum propeller for both defined objectives instead of only considering one of them, as in previous studies. Then, based on the optimized parameters, the propeller performance is calculated in open-water conditions. From the computed results, one can observe the importance of considering the hull–propulsor interaction in propeller selection.