Design of Portable New Intelligence Thermometer for Newborn Household

Objective: Design of a portable new intelligent thermometer for newborns using thermo sensitive materials, to compare three different thermometers, in terms of safety, accuracy and effectiveness. Methods: Three thermometers for home use (New Thermometer, Electronic Thermometers and Mercury thermometers) were applied to 20 neonatal patients during 24 h, and the measured values of the three sites of the newborn baby. Results: Pearson correlation all revealed moderate correlation, between the Mercury thermometers and the New Thermometer (cervical r¼0.759, pulmonary arterial catheter body surface projection area r¼0.502, left axillary area r¼0.781), between the Mercury thermometers and the electronic thermometers (cervical r¼0.694, pulmonary arterial catheter body surface projection area r¼0.580, left axillary area r¼0.760) systems, Two thermometers measured in different parts than mercury thermometers R value (0.502 to 0.781). The difference is not statistically significant in the temperature values measured by the new thermometer at the neck and under the left armpit (P≥0.05), the difference between digital thermometers and mercury thermometers is no statistically significant (P≥0.05). Conclusion: The new thermometer is easy to use, safe and stable, and can measure the core body temperature noninvasively. The accuracy of the new thermometer in the projection area of pulmonary artery surface needs further study.

Evaluation and Management of ST-elevation Myocardial Infarction and Shock

Cardiogenic shock is the deadliest complication of acute ST-elevation myocardial infarction. Prompt recognition and intervention are critical for patient survival. The diagnosis of cardiogenic shock is primarily a clinical one based on signs and symptoms of low cardiac output and heart failure, and can be confirmed with placement of a pulmonary arterial catheter. Vasopressor and inotropic therapies are typically required, and in severe cases, an intra-aortic balloon pump can provide additional haemodynamic support. Although mortality for cardiogenic shock associated with ST-elevation myocardial infarction remains high, early reperfusion strategies primarily via percutaneous coronary intervention or coronary artery bypass graft surgery have led to improved outcomes.

Measurement of Cardiac Output by Pulse Dye Densitometry Using Indocyanine Green

Background A new method for determining cardiac output (CO, l/min) using dye dilution combined with pulse dye densitometry (PDD), based on the principle of pulse oximetry, has been developed. The aim of the study was to determine the accuracy and precision of PDD by comparing it with the thermodilution method. Methods A prospective study was performed in 22 patients having surgery who were monitored using a pulmonary arterial catheter. In addition to the catheter, a specially designed photodetector was placed on the nasal wing. Ten milliliters of ice-cold indocyanine green dissolved in a 5% glucose solution (0.5 mg/ml) was injected. The dye and thermal dilution curves were simultaneously measured to calculate CO. Three to six injections were performed before and after surgery. Paired data were assessed in absolute terms, and the percentage errors were calculated by the degree of agreement and compared at three levels of CO (low < or = 3.5 < medium < or = 6 < high) by analysis of variance. Results The mean and SDs of the differences between dye and thermodilution CO were 0.16 +/- 0.80 l/min or 4.5 +/- 19.6% for 191 paired data. Measurement after surgery failed in one patient. The percentage error with low CO (9.3 +/- 19.3%) was greater (P < 0.05) than those obtained with other CO. Conclusions Pulse dye densitometry could measure CO repeatedly in patients having major surgery with the same degree of accuracy as the thermodilution method; however, a considerable degree of error was observed in some patients.