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2022 ◽  
Vol 12 ◽  
Author(s):  
Iacopo Lanini ◽  
Debora Tringali ◽  
Rosapia Lauro Grotto

Brain tumors are a common form of solid tumors in children and, unfortunately, they are characterized by a very uncertain prognosis. The treatment of this pathology often includes one or more very invasive surgical procedures, quite often in the very first steps of the treatment. Cases of brain tumors in children represent one of the greatest challenges for health care professionals in the domain of pediatric neurosurgery. This is clearly due to the complexity of the therapeutic plan, but also to the nature of the bond that is established between the child, the parents, and the members of the staff during the often-dramatic initial phase of the illness. In this phenomenological-hermeneutic study, we explore both the emotional and organizational needs, as well as the available professional and personal resources of the staff in the Neurosurgery ward of the Meyer Children’s Hospital in Florence (Italy). The ward staff, composed of 7 surgeons, a pediatric neuro-oncologist, 12 nurses, and 4 auxiliary health care professionals, underwent in-depth interviews that were recorded (with the consensus of the participants). The recordings were then transcribed and submitted to content analysis according to COREQ standards. A complex picture of emotional as well as organizational demands emerged from the data. Shared experiences were pointed out, together with more specific and idiosyncratic contents characteristic of different professional roles. The focus of the present paper was twofold, first, we considered the needs that are overtly expressed by the staff, and then we discussed the main sources of their motivational drives. We found that the latter is mainly found in the quality of the therapeutic bond that is established with the children and the family members, together with the deep interest in one’s own professional activity and the effective complementarity and integration of the personal and professional qualities of the staff members within the multidisciplinary caring group.


2022 ◽  
pp. 571-588
Author(s):  
Maria Prosperina Vitale ◽  
Maria Carmela Catone ◽  
Ilaria Primerano ◽  
Giuseppe Giordano

The present study focuses on the usefulness of social network analysis in unveiling network patterns in social media. Specifically, the propagation and consumption of information on Twitter through network analysis tools are investigated to discover the presence of specific conversational patterns in the derived online data. The choosing of Twitter is motivated by the fact that it induces the definition of relationships between users by following communication flows on specific topics of interest and identifying key profiles who influence debates in the digital space. Further lines of research are discussed regarding the tools for discovering the spread of fake news. Considerable disinformation can be generated on social networks, offering a complex picture of informational disorientation in the digital society.


Author(s):  
Péter Pátrovics

The present paper deals with two universal linguistic phenomena, homeostasis and compensation. The author examines their function in relation to two categories, aspect and tense in the history of the Slavic languages. It is beyond doubt that one of the most important categories of the Slavic verb is aspect the origin of which may lie in the Proto-Indo-European language. The effects of its emergence as a verbal category were far-reaching and can be well traced in the history of the most Slavic languages. Taking a close look to the linguistic data, it seems quite obvious that the category of tense and aspect were closely related and did interact, creating different patterns in modern Slavic languages. A certain competition between the category of aspect and that of tense can already be observed in Old Slavic and also in Old Russian and Old Polish where tenses like the aorist and the imperfect were becoming increasingly obsolete. The perfect, on the contrary, has gained ground, while the pluperfect has almost completely fallen into disuse. In the further development, the aspectual opposition also extended to the future tenses thereby affecting the entire tense system. This scenario took place everywhere in the East and West Slavic languages with some nuanced differences. Consequently, in the aspect-tense system of the modern East and West Slavic languages the tendency of the category of aspect to prevail over the category of tense together with the gradual decline in the number of tenses seems to be quite clear. The South Slavic languages, however, have taken a slightly different path showing perhaps the most complex picture. Although the Serbian and Croatian languages have preserved the old tenses, their use is rather limited. In terms of their aspectual development, these languages are getting closer and closer to the Eastern and Western Slavic language groups. In contrast, in Bulgarian and Macedonian one can see an intricate interplay of the aspectual system and the developed tense system. In the case of the change of the different Slavic languages, the phenomenon of linguistic compensation can be observed in all cases on the example of aspect and tense categories as the main means of striving to maintain linguistic homeostasis. Keywords: linguistic homeostasis, compensation, aspect, tense, Old Slavic, Slavic languages, Polish


2021 ◽  
pp. 107808742110649
Author(s):  
Wonhyuk Cho ◽  
Daewook Kim ◽  
Angela Y. S. Park

Local governments are leading sustainability efforts through a range of initiatives, often voluntarily. While a spate of research exists to explain what drives these voluntary decisions, we are still limited in understanding how localities follow through with the resources to implement their adopted plans. This is particularly the case for environment and climate protection programs that are transboundary in nature and thus require more innovative and longer-term approaches than those that are relatively low-cost and easier to implement with future savings. This research examines local investment in promoting three of these program areas: air quality, biodiversity preservation, and ecological restoration. It investigates how local governments vary according to resource commitment and what factors explain those variations. We find several factors significant, including community capacity, political ideology, and institutional arrangements for service production and delivery. Variations are, however, found across different types of resource commitment, suggesting a more complex picture of local resource availability for advancing sustainability efforts.


Viruses ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2529
Author(s):  
Monika Olech ◽  
Jacek Kuźmak

Small ruminant lentiviruses (SRLVs) are a group of highly divergent viruses responsible for global infection in sheep and goats. In a previous study we showed that SRLV strains found in mixed flocks in Poland belonged to subtype A13 and A18, but this study was restricted only to the few flocks from Małopolska region. The present work aimed at extending earlier findings with the analysis of SRLVs in mixed flocks including larger numbers of animals and flocks from different part of Poland. On the basis of gag and env sequences, Polish SRLVs were assigned to the subtypes B2, A5, A12, and A17. Furthermore, the existence of a new subtypes, tentatively designed as A23 and A24, were described for the first time. Subtypes A5 and A17 were only found in goats, subtype A24 has been detected only in sheep while subtypes A12, A23, and B2 have been found in both sheep and goats. Co-infection with strains belonging to different subtypes was evidenced in three sheep and two goats originating from two flocks. Furthermore, three putative recombination events were identified within gag and env SRLVs sequences derived from three sheep. Amino acid (aa) sequences of immunodominant epitopes in CA protein were well conserved while Major Homology Region (MHR) had more alteration showing unique mutations in sequences of subtypes A5 and A17. In contrast, aa sequences of surface glycoprotein exhibited higher variability confirming type-specific variation in the SU5 epitope. The number of potential N-linked glycosylation sites (PNGS) ranged from 3 to 6 in respective sequences and were located in different positions. The analysis of LTR sequences revealed that sequences corresponding to the TATA box, AP-4, AML-vis, and polyadenylation signal (poly A) were quite conserved, while considerable alteration was observed in AP-1 sites. Interestingly, our results revealed that all sequences belonging to subtype A17 had unique substitution T to A in the fifth position of TATA box and did not have a 11 nt deletion in the R region which was noted in other sequences from Poland. These data revealed a complex picture of SRLVs population with ovine and caprine strains belonging to group A and B. We present strong and multiple evidence of dually infected sheep and goats in mixed flocks and present evidence that these viruses can recombine in vivo.


2021 ◽  
Vol 13 (2021/1) ◽  
Author(s):  
Beatrix Mecsi

Following the Confucian period of the Chosŏn era, which overshadowed Buddhists and confined them to the margins of society, at the beginning of Japanese colonial rule the possibility of monastic marriage typical of Japanese practice emerged as a viable alternative for Korean Buddhists in the early twentieth century. While the repressive memory of Japanese colonial heritage often appears in the relevant literature about clerical marriage today as the main reason for Korean Buddhists to get married, an analysis of contemporary documents presents us with a much more complex picture. Most notably among Korean intellectuals, one of the most significant personalities of the era, Manhae Han Young’un’s (1879−1944) systematically urged the reform of Korean Buddhism, Chosŏn Pulgyo yusinnon 朝鮮 佛 敎 維新 論 (Treatise on the Restoration of Korean Buddhism). In connection with the presentation and circumstances of the thirteenth point formulated to allow polemics and the practice of priestly marriage, we can see that his Confucian education, personality, and life play as important a part in his reasoning as the ideologies of the era, social Darwinism and modernism, and democracy. But primary sources revealing the daily lives and circumstances of the monks also show that thewillingness to marry was also greatly influenced by the new inheritance rules introduced in the Japanese colonial system.


2021 ◽  
pp. 089011712110607
Author(s):  
Tyler Prochnow ◽  
Megan S. Patterson

Objective Social network analysis (SNA) can measure social connectedness and assess impact of interpersonal connections on health behaviors, including physical activity (PA). This paper aims to systematically review adult PA studies using SNA to understand important social network concepts relative to PA. Data Source A search was performed using PsycINFO, MEDLINE, PubMed, and Web of Science. Study Inclusion and Exclusion Criteria To be included in the search, articles needed to 1) include a measure of PA, 2) conduct an SNA in which specific relationships were measured, and 3) conduct an analysis between social network measures and PA. Data Extraction Key study elements including network design and results were extracted. Data Synthesis Data were synthesized to answer 2 questions: 1) how has adult PA been investigated using SNA approaches and 2) how is an adult’s social network associated with PA behaviors? Results A final sample of 28 articles remained from an initial 11 085 articles. Network size, homophily, network composition, and network exposure to PA were all associated with individual level PA across studies. Lastly, longitudinal and intervention studies showed a more complex picture of social influence and diffusion of PA behavior. Conclusions Adults’ PA behaviors are influenced by their networks. Capitalizing on this influence, researchers should engage not just individual behavior change but also the social influences present within the person’s life.


2021 ◽  
Vol 12 ◽  
Author(s):  
Pranav S. Ambadi ◽  
Kristin Basche ◽  
Rebecca L. Koscik ◽  
Visar Berisha ◽  
Julie M. Liss ◽  
...  

Clinical assessments often use complex picture description tasks to elicit natural speech patterns and magnify changes occurring in brain regions implicated in Alzheimer's disease and dementia. As The Cookie Theft picture description task is used in the largest Alzheimer's disease and dementia cohort studies available, we aimed to create algorithms that could characterize the visual narrative path a participant takes in describing what is happening in this image. We proposed spatio-semantic graphs, models based on graph theory that transform the participants' narratives into graphs that retain semantic order and encode the visuospatial information between content units in the image. The resulting graphs differ between Cognitively Impaired and Unimpaired participants in several important ways. Cognitively Impaired participants consistently scored higher on features that are heavily associated with symptoms of cognitive decline, including repetition, evidence of short-term memory lapses, and generally disorganized narrative descriptions, while Cognitively Unimpaired participants produced more efficient narrative paths. These results provide evidence that spatio-semantic graph analysis of these tasks can generate important insights into a participant's cognitive performance that cannot be generated from semantic analysis alone.


2021 ◽  
Author(s):  
Yeray Santana-Falcón ◽  
Roland Seferian

Abstract Temperature is one of the most important drivers of global ocean patterns of biodiversity1,2,3 shaping thermal niches through thresholds of physiological thermal tolerance4⁠. Because of anthropogenic global warming, lower and upper thermal niche bounds are predicted to change affecting the future distribution of marine species5,6⁠. Current working hypotheses suggest an expansion of ectotherms toward their poleward boundaries7,8. Nonetheless, the knowledge of the timing and extent of these rearrangements across latitude and depth remains limited. Here, using daily data across the water column from both Ocean Sites network observations and novel Earth System Model, we track the emergence of thermal niches whose lower bound is warmer than their current upper bound, potentially disrupting marine habitats. We show that these developments will emerge by ~2030 in subsurface waters (~50 – 1000 m) if anthropogenic emissions continue to rise, whereas they delay several decades if emissions are substantially reduced. By 2100, thermal niches will be warmer than current counterparts. However, we further show that depending on the vertical level, concomitant changes in both boundaries will result in wider or narrower thermal niches. These results suggest that the redistribution of marine species might differ across depth, shedding light upon a much more complex picture of the impact of climate change on marine habitats.


2021 ◽  
Author(s):  
◽  
Matthew Soar

<p>This thesis draws on social constructivist theories of scientific knowledge to analyse the public engagement practices of a cohort of scientist-communicators in Aotearoa as they represent scientific complexity, risk, and uncertainty in public. Through semi-structured interviews and thematic analysis, this thesis demonstrates that participants think defensively about the publics they communicate to, drawing boundaries between science and publics that minimise exposure of the elements of scientific knowledge they perceive might undermine scientific authority. Such boundary-work often demarcates public engagement from scientific knowledge production, constructing public engagement as a subjective process applied to scientific knowledge after the fact. These science-communicators also work to overcome these very same boundaries by making science more accessible and democratic. Such tensions suggest that participants not only socially construct science, but also contribute to the social construction of public engagement with science as they work to transform systemic and cultural barriers acting to entrench science as an inaccessible, exclusive, and unilateral arbiter of knowledge. In doing so, participants found that presenting a more accurate, complex picture of science—with all its uncertainties and failures—had not undermined public confidence in science. Instead, complexity, risk and uncertainty could become transparent elements of scientific knowledge production, thereby open to public scrutiny and definition. Participants’ representations of complexity, risk, and uncertainty were influenced by accessible, local publications, and economic and institutional conditions, but rarely by established public engagement scholarship.</p>


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