Effect of Glutamine Supplementation on Muscular Damage Biomarkers in Professional Basketball Players

Scientific evidence supports the role of L-glutamine in improving immune function. This could suggest a possible role of L-glutamine in recovery after intense exercise. To this end, the present report aimed to study if oral L-glutamine supplementation could attenuate muscle damage in a group of players of a mainly eccentric sport discipline such as basketball. Participants (n = 12) were supplemented with 6 g/day of glutamine (G group) or placebo (P group) for 40 days in a crossover study design (20 days with glutamine + 20 days with placebo and vice versa). Blood samples were obtained at the beginning and at the end of each period and markers from exercise-induced muscle damage were determined. The glutamine supplemented group displayed significantly low values of aspartate transaminase, creatine kinase and myoglobin in blood, suggesting less muscle damage compared to the placebo. In addition, adrenocorticotropic hormone levels were lower in the glutamine supplemented group than in the placebo. As a result, the circulating cortisol levels did not increase at the end of the study in the glutamine supplemented group. Altogether, the results indicate that glutamine could help attenuate exercise-induced muscle damage in sport disciplines with predominantly eccentric actions.

Impact of Rest-Redistribution on Fatigue During Maximal Eccentric Knee Extensions

Redistributing long inter-set rest intervals into shorter but more frequent rest intervals generally maintains concentric performance, possibly due to improved energy store maintenance. However, eccentric actions require less energy than concentric actions, meaning that shorter but more frequent sets may not affect eccentric actions to the same degree as concentric actions. Considering the increased popularity of eccentric exercise, the current study evaluated the effects of redistributing long inter-set rest periods into shorter but more frequent rest periods during eccentric only knee extensions. Eleven resistance-trained men performed 40 isokinetic unilateral knee extensions at 60°·s−1 with 285 s of total rest using traditional sets (TS; 4 sets of 10 with 95 s inter-set rest) and rest-redistribution (RR; 20 sets of 2 with 15 s inter-set rest). Before and during exercise, muscle oxygenation was measured via near-infrared spectroscopy, and rating of perceived exertion (RPE) was recorded after every 10th repetition. There were no differences between protocols for peak torque (RR, 241.58±47.20 N; TS, 231.64±48.87 N; p=0.396) or total work (RR, 215.26±41.47 J; TS, 209.71±36.02 J; p=0.601), but moderate to large effect sizes existed in later repetitions (6,8,10) with greater peak torque during RR (d=0.66-1.19). For the entire session, RR had moderate effects on RPE (RR, 5.73±1.42; TS, 6.09±1.30; p=0.307; d=0.53) and large effects on oxygen saturation (RR, 5857.4±310.0; TS, 6495.8±273.8; p=0.002, d=2.13). Therefore, RR may maintain peak torque or total work during eccentric exercise, improve oxygen utilization at the muscle, and reduce the perceived effort.

Post-Activation Potentiation on Squat Jump Following Two Different Protocols: Traditional vs. Inertial Flywheel

Post‐activation potentiation (PAP) has been defined as a major enhancement of muscular performance following a preload stimulus. The eccentric actions seem to cause a potentiating effect on subsequent explosive exercises. The aim of this study was to determine whether a protocol of squat exercise using an inertial flywheel could have a potentiating effect on jump performance. Sixteen physically active volunteers participated in the study (age: 21.8 ± 2.7 years; body mass index: 23.6 ± 3). All participants completed two different protocols on separate days: a Traditional Protocol (using a half squat with a guided barbell) and an Inertial Flywheel Protocol (using a half squat with an inertial flywheel). Both protocols were similar and consisted of 3 x 6 reps at the load that maximized power, with a 3‐minute rest interval between sets. The squat jump (SJ) was measured by a contact platform at baseline, and four, eight and twelve minutes after the PAP stimulus. A two‐way ANOVA with repeated measures was performed to analyze significant differences over time. There were significant increases of SJ height (p = 0.004, d = 0.665), velocity (p = 0.003, d = 0.688) and power (p = 0.004, d = 0.682) from baseline after the inertial flywheel protocol. A significant interaction effect (time x protocol) was observed, showing that the inertial flywheel protocol had a potentiating effect on the jump performance compared to the traditional protocol, more specifically at 4 and 8 minutes after the PAP stimulus. In conclusion, the inertial flywheel protocol showed a potentiating effect on the squat jump performance, thus this pre‐ conditioning activity could be useful during the warm‐up before the competition.

Brain activation differences between muscle actions for strength and fatigue: A brief review.

BACKGROUND: Brain activation differences for strength and fatigue have recently been investigated due to advancements in brain-imaging methods.AIM: To review brain activation differences between concentric, eccentric and isometric muscle actions for strength and fatigue.METHODS: 12 studies were selected by accessing PubMed and Web of Knowledge databases.RESULTS: Collectively, the literature demonstrates that for strength the parietal and frontal lobes of the cortex that control movement preparation, planning and execution, and process feedback information are more activated during eccentric than concentric actions. In the supplementary motor area, event-related desynchronization is continued for both concentric and eccentric actions, but only present at the beginning and end of isometric actions. This indicates the CNS specifically controls each of these muscle actions. For fatigue, cortical activation is greater in the supplementary and premotor areas during isometric actions, but may be greater primarily in the central, occipital and parietal cortical areas for concentric and eccentric actions.INTERPRETATION:Muscular strength can be elicited with eccentric actions to more effectively activate control and memory of movement in the parietal and frontal lobes. Muscular fatigue can be elicited with isometric actions to selectively activate supplementary and premotor areas, or with concentric and eccentric actions for central, occipital and parietal cortical areas.