This chapter aims to address the quantum signal role and properties in optical fiber application mainly in quantum communication. It covers the general discussion on quantum bits and optical waveguiding properties. The highlight of this chapter lies in the discussion of the quantum fictitious force of anti-centrifugal force which was first reported in 2001. Under this condition, the free particle experience an attractive potential towards the rotating center of a bent waveguide structure. A lot of theoretical work has been carried out to observe this quantum phenomenon. However, no intensive experimental work has been carried out to date. With the advancement of nano-fabrication technology and quantum experimental, it provides a bright potential to observe these phenomena. Thus, we proposed a promising material of Lithium Niobate on Insulator to serve as a waveguiding platform to study this quantum effect experimentally. The discussion is extended to perceive the relation between Schrodinger and Helmholtz’s equation corresponding to this effect.