Analyzing optical TDMA to mitigate interference in downlink LiFi optical attocell networks

Co-channel interference in the downlink of LiFi attocell networks significantly decreases the network performance in terms of rate. Analysis of multiple access schemes is essential to mitigate interference and improve rate. The light-emitting diodes (LEDs) being centrally monitored, the time division multiple access (TDMA) scheme over the LEDs will be suitable to analyze. This work considers the interference characterization in Ref. (Surampudi A, Ganti RK. Interference characterization in downlink Li-Fi optical attocell networks. J Lightwave Technol 2018;36:3211–28) over M-PAM modulated signals to derive an exact expression for the goodput G of the time scheduled attocell network, which is arranged as a deterministic square lattice in two dimensions. Given this TDMA over the LEDs, numerical simulations show that the LEDs can be optimally time scheduled to maximize the goodput, which implies that the TDMA mitigates interference in an attocell network compared to the case when the LEDs are unscheduled.

Relapsed ALL: CAR T vs transplant vs novel therapies

Chimeric antigen receptor T-cell therapy targeting CD19 (CART19) has expanded the treatment options for patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (ALL). The approval of tisagenlecleucel for pediatric and young adult patients with r/r ALL has allowed broader access for some patients, but the treatment of older adults is available (at the time of this writing) only within a clinical trial. High remission rates have been consistently observed with varied CART19 products and treatment platforms, but durability of remissions and thus the potential role of a consolidative allogeneic stem cell transplant (SCT) is more uncertain and likely to vary by product and population treated. The immunologic characteristics of CARTs that confer high response rates also account for the life-threatening toxicities of cytokine release syndrome and immune effector cell–associated neurotoxicity syndrome, the severity of which also varies by patient and disease characteristics and product. Further considerations informing a decision to treat include feasibility of leukapheresis and timeline of manufacture, alternative treatment options available, and the appropriateness of a potential consolidative allogeneic SCT. Advances in the field are under way to improve rate and duration of responses and to mitigate toxicity.

1432 Simplifying Processes to Improve Rate of Surgical Site Infections

Aim Surgical site infection (SSI) is a common healthcare associated infection, complicating 10-15% of operations. These have the potential to cause significant harm to patients, prolong hospital stays and are costly to the NHS. Although the cause is multifactorial, appropriate antibiotic prophylaxis plays a role in reducing SSIs. Due to a higher-than-average rate of SSIs at ASPH, an audit was performed to review the use of antibiotics prior to surgery. Method Local antibiotic policies for surgical prophylaxis were used as the audit standard. Data was collected prospectively over a two-week period. Recovery nurses filled out a proforma identifying type of surgery, patients’ weight, antibiotics received and dose. Results 120 datasets were collected. Due to incomplete data, 113 were analysed; 81 patients required prophylactic antibiotics. The audit identified that current practice was not aligned with local policy. Where antibiotic use was indicated, all bar one patient received appropriate antibiotics. The primary issue identified was incorrect gentamicin dosing when a 5mg/kg dose based on creatine clearance was required. Gentamicin was dosed appropriately in 15 out of 49 cases, with 160mg administered in most cases regardless of policy. Conclusions Reasons underlying this are likely to be multifactorial, including ototoxicity risk, dose calculation and administration time; at present, the scheduling of theatre cases does not allow for a 30-minute gap from induction of anaesthesia to start of surgery. Working in partnership with the microbiologists we plan to create a gentamicin dose reference chart for display in all anaesthetic rooms to simplify dosing and improve compliance.

157 Effects of Monensin and Protein Type on Performance of Yearling Steers Grazing Smooth Brome

A two-yr study was conducted to evaluate the effects of monensin on sparing ruminal degradable protein in yearling steers grazing smooth bromegrass pastures (n = 288, initial BW = 332 kg, SD = 7). Treatment design was a 2 x 3 factorial with the following factors: 1) 0 or 200 mg monensin/steer daily; 2) no protein supplement, 1.25 kg soybean meal (SBM) as a source of RDP, or 1.31 kg non-enzymatically browned SBM as a source of RUP. Steers receiving supplemental protein were provided isonitrogenous amounts equivalent to dried distillers grains plus solubles at 0.50% BW. Steers were weighed approximately every 34 d to adjusted the amount of protein supplement. There was no interaction (P > 0.41) of monensin by protein type for average daily gain (ADG). Rate of gain for steers supplemented monensin was not different (P = 0.26) from steers not supplemented monensin. However, monensin supplemented steers numerically gained 7.9% more than steers not provided monensin when no supplemental protein was provided. Compared to steers supplemented with no protein, supplementing RDP increased ADG by 0.19 kg/steer (P < 0.001). Likewise, RUP supplementation increased ADG by 0.24 kg/steer (P < 0.001) compared to steers supplemented no protein. Supplementing RUP increased ADG by 0.05 kg/steer (P < 0.001) compared to steers supplemented RDP. Supplementing protein, especially rumen undegradable protein, improved yearling steer rate of gain on smooth bromegrass pastures. Monensin supplementation did not improve rate of gain. These data do not support the protein-sparing effects of monensin for steers supplemented with RDP.

Simulating Drillstring Dynamics Motion and Post-Buckling State with Advanced Transient Dynamics Model

Summary As drilling sections become deeper and longer, transferring more weight downhole to improve rate of penetration is the primary concern for the operator. Drillstring dynamics and buckling are some primary limiters for drilling efficiency. Aggressive drilling parameters may lead to severe downhole dynamics, which leads to cutter breakage and tool damage. When axial compression exceeds a certain threshold, the drillstring buckles sinusoidally inside the wellbore first, followed by helical buckling. Buckling leads to accelerated joint wear, tool fatigue failures, and lower drilling efficiency. To better manage drillstring dynamics and buckling, we propose a method of simulating drillstring dynamics motion and postbuckling state using an advanced transient dynamics model. An analysis methodology was developed on the basis of the finite element transient dynamics model. The model captures the enriched physics of drillstring dynamics and loading: the large deformation of buckled drillstring, the strong nonlinearity of contact and friction forces, and the dynamically triggered instability caused by drilling rotation. Transient dynamics simulations are conducted for drillstring with the actual well trajectory and rotation speed. The weight on bit (WOB) is ramped up gradually, and the drillstring deformation is monitored to detect the onset of buckling or dynamics instability. To conduct the model validation, the buckling inception loads predicted by the model are compared against the analytical equation of critical buckling loads. A field extended reach drilling (ERD) job was simulated by the model. The downhole weight and torque data from the measurement-while-drilling (MWD) tool was used to validate the weight transfer prediction by the model. Most existing buckling theories use the analytical equations of critical buckling load, which were normally derived on the basis of the idealized assumptions, such as perfect wellbore shape and uniform tubular geometry. The proposed method simulates the drillstring behaviors in the field drilling conditions and aims to capture effects of wellbore friction and string rotation. The transient dynamics model is capable of simulating drillstring dynamics movement (whirling and snaking) and weight lockup under severe helical buckling. An automatic method is proposed to interpret the drillstring behaviors from the simulation results. Using the transient dynamics model, the procedure presented in this article can simulate the dynamics and buckling behaviors of drillstring and help mitigate associated risks in well-planning and execution phases.

A Journey to Cherish; How Transformational Leadership Affects Project Success through Team Performance

Purpose: The study aims to explain the role of transformational leadership style in mediating team performance and its affect on project success.Approach/Methodology/Design: The method of determining the sample used is random sampling. The study population is construction companies in Pakistan. The sample used was a size of230subordinates as respondents. Data collection is done through survey by distributing questionnaires offline that have been tested for validity and reliability. The data analysis technique used is the SEM-PLS Analysis.Findings: The results showed that transformational leadership variable positively and significantly affects project success.Transformational leadership has a positive relationship with team performance and team performance also has a positive relation with project success. This study also proves the direct and indirect affect of transformational leadership on project success.Practical Implication: Therefore, transformational leadership provides a clear understanding to improve rate of project success and team performance.Originality/Value:Increasing team performance strategy can significantly mediate the affect of transformational leadership on project success in construction sector of Pakistan.

Superior rate-capability and long-lifespan carbon nanotube-in-nanotube@Sb2S3 anode for lithium-ion storage

It is vital to improve rate capability and cycling performance of Sb2S3 to promote its application in lithium-ion batteries. Herein, Sb2S3 is successfully anchored inside carbon nanotube-in-nanotube via a multi-step...

Controllable preparation of one-dimensional Li1.2Mn0.54Ni0.13Co0.13O2 cathode materials for high-performance lithium-ion batteries

Li1.2Mn0.54Ni0.13Co0.13O2 rods with controllable sizes were synthesized via a co-precipitation route followed by a post-calcination treatment to improve rate capabilities.